BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

210 related articles for article (PubMed ID: 22348073)

  • 1. Exogenous ether lipids predominantly target mitochondria.
    Kuerschner L; Richter D; Hannibal-Bach HK; Gaebler A; Shevchenko A; Ejsing CS; Thiele C
    PLoS One; 2012; 7(2):e31342. PubMed ID: 22348073
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Lipid rafts, endoplasmic reticulum and mitochondria in the antitumor action of the alkylphospholipid analog edelfosine.
    Gajate C; Mollinedo F
    Anticancer Agents Med Chem; 2014 May; 14(4):509-27. PubMed ID: 24628241
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Involvement of lipid rafts in the localization and dysfunction effect of the antitumor ether phospholipid edelfosine in mitochondria.
    Mollinedo F; Fernández M; Hornillos V; Delgado J; Amat-Guerri F; Acuña AU; Nieto-Miguel T; Villa-Pulgarín JA; González-García C; Ceña V; Gajate C
    Cell Death Dis; 2011 May; 2(5):e158. PubMed ID: 21593790
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Antitumor alkyl-lysophospholipid analog edelfosine induces apoptosis in pancreatic cancer by targeting endoplasmic reticulum.
    Gajate C; Matos-da-Silva M; Dakir el-H; Fonteriz RI; Alvarez J; Mollinedo F
    Oncogene; 2012 May; 31(21):2627-39. PubMed ID: 22056873
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Endoplasmic reticulum stress in the proapoptotic action of edelfosine in solid tumor cells.
    Nieto-Miguel T; Fonteriz RI; Vay L; Gajate C; López-Hernández S; Mollinedo F
    Cancer Res; 2007 Nov; 67(21):10368-78. PubMed ID: 17974980
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Drug uptake, lipid rafts, and vesicle trafficking modulate resistance to an anticancer lysophosphatidylcholine analogue in yeast.
    Cuesta-Marbán Á; Botet J; Czyz O; Cacharro LM; Gajate C; Hornillos V; Delgado J; Zhang H; Amat-Guerri F; Acuña AU; McMaster CR; Revuelta JL; Zaremberg V; Mollinedo F
    J Biol Chem; 2013 Mar; 288(12):8405-8418. PubMed ID: 23335509
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mitochondria and lipid raft-located FOF1-ATP synthase as major therapeutic targets in the antileishmanial and anticancer activities of ether lipid edelfosine.
    Villa-Pulgarín JA; Gajate C; Botet J; Jimenez A; Justies N; Varela-M RE; Cuesta-Marbán Á; Müller I; Modolell M; Revuelta JL; Mollinedo F
    PLoS Negl Trop Dis; 2017 Aug; 11(8):e0005805. PubMed ID: 28829771
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ether--lipid (alkyl-phospholipid) metabolism and the mechanism of action of ether--lipid analogues in Leishmania.
    Lux H; Heise N; Klenner T; Hart D; Opperdoes FR
    Mol Biochem Parasitol; 2000 Nov; 111(1):1-14. PubMed ID: 11087912
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Induction of apoptosis in human mitogen-activated peripheral blood T-lymphocytes by the ether phospholipid ET-18-OCH3: involvement of the Fas receptor/ligand system.
    Cabaner C; Gajate C; Macho A; Muñoz E; Modolell M; Mollinedo F
    Br J Pharmacol; 1999 Jun; 127(4):813-25. PubMed ID: 10433487
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cell membranes and apoptosis: role of cardiolipin, phosphatidylcholine, and anticancer lipid analogues.
    Wright MM; Howe AG; Zaremberg V
    Biochem Cell Biol; 2004 Feb; 82(1):18-26. PubMed ID: 15052325
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Biological activities, mechanisms of action and biomedical prospect of the antitumor ether phospholipid ET-18-OCH(3) (edelfosine), a proapoptotic agent in tumor cells.
    Gajate C; Mollinedo F
    Curr Drug Metab; 2002 Oct; 3(5):491-525. PubMed ID: 12369895
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Endoplasmic reticulum targeting in Ewing's sarcoma by the alkylphospholipid analog edelfosine.
    Bonilla X; Dakir el-H; Mollinedo F; Gajate C
    Oncotarget; 2015 Jun; 6(16):14596-613. PubMed ID: 25999349
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Involvement of raft aggregates enriched in Fas/CD95 death-inducing signaling complex in the antileukemic action of edelfosine in Jurkat cells.
    Gajate C; Gonzalez-Camacho F; Mollinedo F
    PLoS One; 2009; 4(4):e5044. PubMed ID: 19352436
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sensitivity of K562 and HL-60 cells to edelfosine, an ether lipid drug, correlates with production of reactive oxygen species.
    Wagner BA; Buettner GR; Oberley LW; Burns CP
    Cancer Res; 1998 Jul; 58(13):2809-16. PubMed ID: 9661895
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Suppression of metastatic organ colonization and antiangiogenic activity of the orally bioavailable lipid raft-targeted alkylphospholipid edelfosine.
    Alonso-Pérez V; Hernández V; Calzado MA; Vicente-Blázquez A; Gajate C; Soler-Torronteras R; DeCicco-Skinner K; Sierra A; Mollinedo F
    Biomed Pharmacother; 2024 Feb; 171():116149. PubMed ID: 38266621
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mitochondrial-derived ROS in edelfosine-induced apoptosis in yeasts and tumor cells.
    Zhang H; Gajate C; Yu LP; Fang YX; Mollinedo F
    Acta Pharmacol Sin; 2007 Jun; 28(6):888-94. PubMed ID: 17506948
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Selective induction of apoptosis in cancer cells by the ether lipid ET-18-OCH3 (Edelfosine): molecular structure requirements, cellular uptake, and protection by Bcl-2 and Bcl-X(L).
    Mollinedo F; Fernández-Luna JL; Gajate C; Martín-Martín B; Benito A; Martínez-Dalmau R; Modolell M
    Cancer Res; 1997 Apr; 57(7):1320-8. PubMed ID: 9102220
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Fluorescent phenylpolyene analogues of the ether phospholipid edelfosine for the selective labeling of cancer cells.
    Quesada E; Delgado J; Gajate C; Mollinedo F; Acuña AU; Amat-Guerri F
    J Med Chem; 2004 Oct; 47(22):5333-5. PubMed ID: 15481970
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ET-18-OCH3 (edelfosine): a selective antitumour lipid targeting apoptosis through intracellular activation of Fas/CD95 death receptor.
    Mollinedo F; Gajate C; Martín-Santamaría S; Gago F
    Curr Med Chem; 2004 Dec; 11(24):3163-84. PubMed ID: 15579006
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effect of anti-tumor ether lipids on ordered domains in model membranes.
    Heczková B; Slotte JP
    FEBS Lett; 2006 May; 580(10):2471-6. PubMed ID: 16638573
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.