BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

363 related articles for article (PubMed ID: 22351782)

  • 1. CutA divalent cation tolerance homolog (Escherichia coli) (CUTA) regulates β-cleavage of β-amyloid precursor protein (APP) through interacting with β-site APP cleaving protein 1 (BACE1).
    Zhao Y; Wang Y; Hu J; Zhang X; Zhang YW
    J Biol Chem; 2012 Mar; 287(14):11141-50. PubMed ID: 22351782
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Role of copper and the copper-related protein CUTA in mediating APP processing and Aβ generation.
    Hou P; Liu G; Zhao Y; Shi Z; Zheng Q; Bu G; Xu H; Zhang YW
    Neurobiol Aging; 2015 Mar; 36(3):1310-5. PubMed ID: 25557959
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
    Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
    Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Alternative Selection of β-Site APP-Cleaving Enzyme 1 (BACE1) Cleavage Sites in Amyloid β-Protein Precursor (APP) Harboring Protective and Pathogenic Mutations within the Aβ Sequence.
    Kimura A; Hata S; Suzuki T
    J Biol Chem; 2016 Nov; 291(46):24041-24053. PubMed ID: 27687728
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Loss of cleavage at β'-site contributes to apparent increase in β-amyloid peptide (Aβ) secretion by β-secretase (BACE1)-glycosylphosphatidylinositol (GPI) processing of amyloid precursor protein.
    Vetrivel KS; Barman A; Chen Y; Nguyen PD; Wagner SL; Prabhakar R; Thinakaran G
    J Biol Chem; 2011 Jul; 286(29):26166-77. PubMed ID: 21642424
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Regulation of Synaptic Amyloid-β Generation through BACE1 Retrograde Transport in a Mouse Model of Alzheimer's Disease.
    Ye X; Feng T; Tammineni P; Chang Q; Jeong YY; Margolis DJ; Cai H; Kusnecov A; Cai Q
    J Neurosci; 2017 Mar; 37(10):2639-2655. PubMed ID: 28159908
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The Golgi-Localized γ-Ear-Containing ARF-Binding (GGA) Proteins Alter Amyloid-β Precursor Protein (APP) Processing through Interaction of Their GAE Domain with the Beta-Site APP Cleaving Enzyme 1 (BACE1).
    von Einem B; Wahler A; Schips T; Serrano-Pozo A; Proepper C; Boeckers TM; Rueck A; Wirth T; Hyman BT; Danzer KM; Thal DR; von Arnim CA
    PLoS One; 2015; 10(6):e0129047. PubMed ID: 26053850
    [TBL] [Abstract][Full Text] [Related]  

  • 8. SEPT8 modulates β-amyloidogenic processing of APP by affecting the sorting and accumulation of BACE1.
    Kurkinen KM; Marttinen M; Turner L; Natunen T; Mäkinen P; Haapalinna F; Sarajärvi T; Gabbouj S; Kurki M; Paananen J; Koivisto AM; Rauramaa T; Leinonen V; Tanila H; Soininen H; Lucas FR; Haapasalo A; Hiltunen M
    J Cell Sci; 2016 Jun; 129(11):2224-38. PubMed ID: 27084579
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Prion protein interacts with BACE1 protein and differentially regulates its activity toward wild type and Swedish mutant amyloid precursor protein.
    Griffiths HH; Whitehouse IJ; Baybutt H; Brown D; Kellett KA; Jackson CD; Turner AJ; Piccardo P; Manson JC; Hooper NM
    J Biol Chem; 2011 Sep; 286(38):33489-500. PubMed ID: 21795680
    [TBL] [Abstract][Full Text] [Related]  

  • 10. BACE1 retrograde trafficking is uniquely regulated by the cytoplasmic domain of sortilin.
    Finan GM; Okada H; Kim TW
    J Biol Chem; 2011 Apr; 286(14):12602-16. PubMed ID: 21245145
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Alzheimer's β-secretase (BACE1) regulates the cAMP/PKA/CREB pathway independently of β-amyloid.
    Chen Y; Huang X; Zhang YW; Rockenstein E; Bu G; Golde TE; Masliah E; Xu H
    J Neurosci; 2012 Aug; 32(33):11390-5. PubMed ID: 22895721
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Intracellular trafficking of presenilin 1 is regulated by beta-amyloid precursor protein and phospholipase D1.
    Liu Y; Zhang YW; Wang X; Zhang H; You X; Liao FF; Xu H
    J Biol Chem; 2009 May; 284(18):12145-52. PubMed ID: 19276086
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Sorting nexin 12 interacts with BACE1 and regulates BACE1-mediated APP processing.
    Zhao Y; Wang Y; Yang J; Wang X; Zhao Y; Zhang X; Zhang YW
    Mol Neurodegener; 2012 Jun; 7():30. PubMed ID: 22709416
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Segregation of the membrane cargoes, BACE1 and amyloid precursor protein (APP) throughout the Golgi apparatus.
    Fourriere L; Cho EH; Gleeson PA
    Traffic; 2022 Mar; 23(3):158-173. PubMed ID: 35076977
    [TBL] [Abstract][Full Text] [Related]  

  • 15. BACE1 elevation engendered by GGA3 deletion increases β-amyloid pathology in association with APP elevation and decreased CHL1 processing in 5XFAD mice.
    Kim W; Ma L; Lomoio S; Willen R; Lombardo S; Dong J; Haydon PG; Tesco G
    Mol Neurodegener; 2018 Feb; 13(1):6. PubMed ID: 29391027
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models.
    Natunen T; Takalo M; Kemppainen S; Leskelä S; Marttinen M; Kurkinen KMA; Pursiheimo JP; Sarajärvi T; Viswanathan J; Gabbouj S; Solje E; Tahvanainen E; Pirttimäki T; Kurki M; Paananen J; Rauramaa T; Miettinen P; Mäkinen P; Leinonen V; Soininen H; Airenne K; Tanzi RE; Tanila H; Haapasalo A; Hiltunen M
    Neurobiol Dis; 2016 Jan; 85():187-205. PubMed ID: 26563932
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Distinct anterograde trafficking pathways of BACE1 and amyloid precursor protein from the TGN and the regulation of amyloid-β production.
    Tan JZA; Fourriere L; Wang J; Perez F; Boncompain G; Gleeson PA
    Mol Biol Cell; 2020 Jan; 31(1):27-44. PubMed ID: 31746668
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The neuronal-specific isoform of BIN1 regulates β-secretase cleavage of APP and Aβ generation in a RIN3-dependent manner.
    Bhattacharyya R; Teves CAF; Long A; Hofert M; Tanzi RE
    Sci Rep; 2022 Mar; 12(1):3486. PubMed ID: 35241726
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Beta-secretase/BACE1 promotes APP endocytosis and processing in the endosomes and on cell membrane.
    Wang M; Jing T; Wang X; Yao D
    Neurosci Lett; 2018 Oct; 685():63-67. PubMed ID: 30120949
    [TBL] [Abstract][Full Text] [Related]  

  • 20. BACE1 Cleavage Site Selection Critical for Amyloidogenesis and Alzheimer's Pathogenesis.
    Zhang S; Wang Z; Cai F; Zhang M; Wu Y; Zhang J; Song W
    J Neurosci; 2017 Jul; 37(29):6915-6925. PubMed ID: 28626014
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.