BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

281 related articles for article (PubMed ID: 22354303)

  • 1. New mutations in the mycobacterial ATP synthase: new insights into the binding of the diarylquinoline TMC207 to the ATP synthase C-ring structure.
    Segala E; Sougakoff W; Nevejans-Chauffour A; Jarlier V; Petrella S
    Antimicrob Agents Chemother; 2012 May; 56(5):2326-34. PubMed ID: 22354303
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Probing the interaction of the diarylquinoline TMC207 with its target mycobacterial ATP synthase.
    Haagsma AC; Podasca I; Koul A; Andries K; Guillemont J; Lill H; Bald D
    PLoS One; 2011; 6(8):e23575. PubMed ID: 21858172
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Diarylquinolines target subunit c of mycobacterial ATP synthase.
    Koul A; Dendouga N; Vergauwen K; Molenberghs B; Vranckx L; Willebrords R; Ristic Z; Lill H; Dorange I; Guillemont J; Bald D; Andries K
    Nat Chem Biol; 2007 Jun; 3(6):323-4. PubMed ID: 17496888
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Variations of subunit {varepsilon} of the Mycobacterium tuberculosis F1Fo ATP synthase and a novel model for mechanism of action of the tuberculosis drug TMC207.
    Biukovic G; Basak S; Manimekalai MS; Rishikesan S; Roessle M; Dick T; Rao SP; Hunke C; Grüber G
    Antimicrob Agents Chemother; 2013 Jan; 57(1):168-76. PubMed ID: 23089752
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Rates and mechanisms of resistance development in Mycobacterium tuberculosis to a novel diarylquinoline ATP synthase inhibitor.
    Huitric E; Verhasselt P; Koul A; Andries K; Hoffner S; Andersson DI
    Antimicrob Agents Chemother; 2010 Mar; 54(3):1022-8. PubMed ID: 20038615
    [TBL] [Abstract][Full Text] [Related]  

  • 6. In vitro antimycobacterial spectrum of a diarylquinoline ATP synthase inhibitor.
    Huitric E; Verhasselt P; Andries K; Hoffner SE
    Antimicrob Agents Chemother; 2007 Nov; 51(11):4202-4. PubMed ID: 17709466
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Genetic basis for natural and acquired resistance to the diarylquinoline R207910 in mycobacteria.
    Petrella S; Cambau E; Chauffour A; Andries K; Jarlier V; Sougakoff W
    Antimicrob Agents Chemother; 2006 Aug; 50(8):2853-6. PubMed ID: 16870785
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Diarylquinolines, synthesis pathways and quantitative structure--activity relationship studies leading to the discovery of TMC207.
    Guillemont J; Meyer C; Poncelet A; Bourdrez X; Andries K
    Future Med Chem; 2011 Sep; 3(11):1345-60. PubMed ID: 21879841
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pharmacokinetics and pharmacodynamics of TMC207 and its N-desmethyl metabolite in a murine model of tuberculosis.
    Rouan MC; Lounis N; Gevers T; Dillen L; Gilissen R; Raoof A; Andries K
    Antimicrob Agents Chemother; 2012 Mar; 56(3):1444-51. PubMed ID: 22155815
    [TBL] [Abstract][Full Text] [Related]  

  • 10. TBAJ-876 Retains Bedaquiline's Activity against Subunits c and ε of
    Sarathy JP; Ragunathan P; Shin J; Cooper CB; Upton AM; Grüber G; Dick T
    Antimicrob Agents Chemother; 2019 Oct; 63(10):. PubMed ID: 31358589
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure of mycobacterial ATP synthase bound to the tuberculosis drug bedaquiline.
    Guo H; Courbon GM; Bueler SA; Mai J; Liu J; Rubinstein JL
    Nature; 2021 Jan; 589(7840):143-147. PubMed ID: 33299175
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ATP Synthase Inhibitors as Anti-tubercular Agents: QSAR Studies in Novel Substituted Quinolines.
    Saxena AK; Alam M
    Curr Top Med Chem; 2020; 20(29):2723-2734. PubMed ID: 32885753
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The structure of the catalytic domain of the ATP synthase from
    Zhang AT; Montgomery MG; Leslie AGW; Cook GM; Walker JE
    Proc Natl Acad Sci U S A; 2019 Mar; 116(10):4206-4211. PubMed ID: 30683723
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mechanism of mycobacterial ATP synthase inhibition by squaramides and second generation diarylquinolines.
    Courbon GM; Palme PR; Mann L; Richter A; Imming P; Rubinstein JL
    EMBO J; 2023 Aug; 42(15):e113687. PubMed ID: 37377118
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Novel antibiotics targeting respiratory ATP synthesis in Gram-positive pathogenic bacteria.
    Balemans W; Vranckx L; Lounis N; Pop O; Guillemont J; Vergauwen K; Mol S; Gilissen R; Motte M; Lançois D; De Bolle M; Bonroy K; Lill H; Andries K; Bald D; Koul A
    Antimicrob Agents Chemother; 2012 Aug; 56(8):4131-9. PubMed ID: 22615276
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The NMR solution structure of Mycobacterium tuberculosis F-ATP synthase subunit ε provides new insight into energy coupling inside the rotary engine.
    Joon S; Ragunathan P; Sundararaman L; Nartey W; Kundu S; Manimekalai MSS; Bogdanović N; Dick T; Grüber G
    FEBS J; 2018 Mar; 285(6):1111-1128. PubMed ID: 29360236
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A diarylquinoline drug active on the ATP synthase of Mycobacterium tuberculosis.
    Andries K; Verhasselt P; Guillemont J; Göhlmann HW; Neefs JM; Winkler H; Van Gestel J; Timmerman P; Zhu M; Lee E; Williams P; de Chaffoy D; Huitric E; Hoffner S; Cambau E; Truffot-Pernot C; Lounis N; Jarlier V
    Science; 2005 Jan; 307(5707):223-7. PubMed ID: 15591164
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Selectivity of TMC207 towards mycobacterial ATP synthase compared with that towards the eukaryotic homologue.
    Haagsma AC; Abdillahi-Ibrahim R; Wagner MJ; Krab K; Vergauwen K; Guillemont J; Andries K; Lill H; Koul A; Bald D
    Antimicrob Agents Chemother; 2009 Mar; 53(3):1290-2. PubMed ID: 19075053
    [TBL] [Abstract][Full Text] [Related]  

  • 19. TMC207: the first compound of a new class of potent anti-tuberculosis drugs.
    Matteelli A; Carvalho AC; Dooley KE; Kritski A
    Future Microbiol; 2010 Jun; 5(6):849-58. PubMed ID: 20521931
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification and synthesis of novel inhibitors of mycobacterium ATP synthase.
    Surase YB; Samby K; Amale SR; Sood R; Purnapatre KP; Pareek PK; Das B; Nanda K; Kumar S; Verma AK
    Bioorg Med Chem Lett; 2017 Aug; 27(15):3454-3459. PubMed ID: 28587823
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.