274 related articles for article (PubMed ID: 22355408)
1. Large aggregates are the major soluble Aβ species in AD brain fractionated with density gradient ultracentrifugation.
Sehlin D; Englund H; Simu B; Karlsson M; Ingelsson M; Nikolajeff F; Lannfelt L; Pettersson FE
PLoS One; 2012; 7(2):e32014. PubMed ID: 22355408
[TBL] [Abstract][Full Text] [Related]
2. The murine version of BAN2401 (mAb158) selectively reduces amyloid-β protofibrils in brain and cerebrospinal fluid of tg-ArcSwe mice.
Tucker S; Möller C; Tegerstedt K; Lord A; Laudon H; Sjödahl J; Söderberg L; Spens E; Sahlin C; Waara ER; Satlin A; Gellerfors P; Osswald G; Lannfelt L
J Alzheimers Dis; 2015; 43(2):575-88. PubMed ID: 25096615
[TBL] [Abstract][Full Text] [Related]
3. Dispersible amyloid β-protein oligomers, protofibrils, and fibrils represent diffusible but not soluble aggregates: their role in neurodegeneration in amyloid precursor protein (APP) transgenic mice.
Rijal Upadhaya A; Capetillo-Zarate E; Kosterin I; Abramowski D; Kumar S; Yamaguchi H; Walter J; Fändrich M; Staufenbiel M; Thal DR
Neurobiol Aging; 2012 Nov; 33(11):2641-60. PubMed ID: 22305478
[TBL] [Abstract][Full Text] [Related]
4. An amyloid-beta protofibril-selective antibody prevents amyloid formation in a mouse model of Alzheimer's disease.
Lord A; Gumucio A; Englund H; Sehlin D; Sundquist VS; Söderberg L; Möller C; Gellerfors P; Lannfelt L; Pettersson FE; Nilsson LN
Neurobiol Dis; 2009 Dec; 36(3):425-34. PubMed ID: 19703562
[TBL] [Abstract][Full Text] [Related]
5. Efficient clearance of Aβ protofibrils in AβPP-transgenic mice treated with a brain-penetrating bifunctional antibody.
Syvänen S; Hultqvist G; Gustavsson T; Gumucio A; Laudon H; Söderberg L; Ingelsson M; Lannfelt L; Sehlin D
Alzheimers Res Ther; 2018 May; 10(1):49. PubMed ID: 29793530
[TBL] [Abstract][Full Text] [Related]
6. Characterization of monomeric and soluble aggregated Aβ in Down's syndrome and Alzheimer's disease brains.
Gkanatsiou E; Sahlin C; Portelius E; Johannesson M; Söderberg L; Fälting J; Basun H; Möller C; Odergren T; Zetterberg H; Blennow K; Lannfelt L; Brinkmalm G
Neurosci Lett; 2021 May; 754():135894. PubMed ID: 33848613
[TBL] [Abstract][Full Text] [Related]
7. Novel multivalent design of a monoclonal antibody improves binding strength to soluble aggregates of amyloid beta.
Rofo F; Buijs J; Falk R; Honek K; Lannfelt L; Lilja AM; Metzendorf NG; Gustavsson T; Sehlin D; Söderberg L; Hultqvist G
Transl Neurodegener; 2021 Sep; 10(1):38. PubMed ID: 34579778
[TBL] [Abstract][Full Text] [Related]
8. Specific uptake of an amyloid-β protofibril-binding antibody-tracer in AβPP transgenic mouse brain.
Magnusson K; Sehlin D; Syvänen S; Svedberg MM; Philipson O; Söderberg L; Tegerstedt K; Holmquist M; Gellerfors P; Tolmachev V; Antoni G; Lannfelt L; Hall H; Nilsson LN
J Alzheimers Dis; 2013; 37(1):29-40. PubMed ID: 23780660
[TBL] [Abstract][Full Text] [Related]
9. The conformational epitope for a new Aβ42 protofibril-selective antibody partially overlaps with the peptide N-terminal region.
Colvin BA; Rogers VA; Kulas JA; Ridgway EA; Amtashar FS; Combs CK; Nichols MR
J Neurochem; 2017 Dec; 143(6):736-749. PubMed ID: 28881033
[TBL] [Abstract][Full Text] [Related]
10. Increased Number of Plasma B Cells Producing Autoantibodies Against Aβ42 Protofibrils in Alzheimer's Disease.
Söllvander S; Ekholm-Pettersson F; Brundin RM; Westman G; Kilander L; Paulie S; Lannfelt L; Sehlin D
J Alzheimers Dis; 2015; 48(1):63-72. PubMed ID: 26401929
[TBL] [Abstract][Full Text] [Related]
11. Aβ42 oligomer-specific antibody ALZ-201 reduces the neurotoxicity of Alzheimer's disease brain extracts.
Sandberg A; Berenjeno-Correa E; Rodriguez RC; Axenhus M; Weiss SS; Batenburg K; Hoozemans JJM; Tjernberg LO; Scheper W
Alzheimers Res Ther; 2022 Dec; 14(1):196. PubMed ID: 36578089
[TBL] [Abstract][Full Text] [Related]
12. Lecanemab demonstrates highly selective binding to Aβ protofibrils isolated from Alzheimer's disease brains.
Johannesson M; Söderberg L; Zachrisson O; Fritz N; Kylefjord H; Gkanatsiou E; Button E; Svensson AS; Rachalski A; Nygren P; Osswald G; Lannfelt L; Möller C
Mol Cell Neurosci; 2024 Jun; 130():103949. PubMed ID: 38906341
[TBL] [Abstract][Full Text] [Related]
13. High-molecular weight Aβ oligomers and protofibrils are the predominant Aβ species in the native soluble protein fraction of the AD brain.
Upadhaya AR; Lungrin I; Yamaguchi H; Fändrich M; Thal DR
J Cell Mol Med; 2012 Feb; 16(2):287-95. PubMed ID: 21418518
[TBL] [Abstract][Full Text] [Related]
14. Sensitive detection of Aβ protofibrils by proximity ligation--relevance for Alzheimer's disease.
Kamali-Moghaddam M; Pettersson FE; Wu D; Englund H; Darmanis S; Lord A; Tavoosidana G; Sehlin D; Gustafsdottir S; Nilsson LN; Lannfelt L; Landegren U
BMC Neurosci; 2010 Oct; 11():124. PubMed ID: 20923550
[TBL] [Abstract][Full Text] [Related]
15. Generation and Partial Characterization of Rabbit Monoclonal Antibody to Pyroglutamate Amyloid-β3-42 (pE3-Aβ).
Mehta PD; Patrick BA; Barshatzky M; Mehta SP; Frackowiak J; Mazur-Kolecka B; Wegiel J; Wisniewski T; Miller DL
J Alzheimers Dis; 2018; 62(4):1635-1649. PubMed ID: 29504532
[TBL] [Abstract][Full Text] [Related]
16. A new class of monoclonal Aβ antibodies selectively targets and triggers deposition of Aβ protofibrils.
Grover S; Pham T; Jones A; Sinobas-Pereira C; Villoch Diaz Maurino M; Garrad EC; Makoni NJ; Parks A; Domalewski RJ; Riggio G; An H; Chen K; Nichols MR
J Neurochem; 2023 Jun; 165(6):860-873. PubMed ID: 37002186
[TBL] [Abstract][Full Text] [Related]
17. Active full-length DNA Aβ
Rosenberg RN; Fu M; Lambracht-Washington D
Alzheimers Res Ther; 2018 Nov; 10(1):115. PubMed ID: 30454039
[TBL] [Abstract][Full Text] [Related]
18. Lack of P-glycoprotein Results in Impairment of Removal of Beta-Amyloid and Increased Intraparenchymal Cerebral Amyloid Angiopathy after Active Immunization in a Transgenic Mouse Model of Alzheimer's Disease.
Bruckmann S; Brenn A; Grube M; Niedrig K; Holtfreter S; von Bohlen und Halbach O; Groschup M; Keller M; Vogelgesang S
Curr Alzheimer Res; 2017; 14(6):656-667. PubMed ID: 27915995
[TBL] [Abstract][Full Text] [Related]
19. Detection of peri-synaptic amyloid-β pyroglutamate aggregates in early stages of Alzheimer's disease and in AβPP transgenic mice using a novel monoclonal antibody.
Mandler M; Rockenstein E; Ubhi K; Hansen L; Adame A; Michael S; Galasko D; Santic R; Mattner F; Masliah E
J Alzheimers Dis; 2012; 28(4):783-94. PubMed ID: 22064070
[TBL] [Abstract][Full Text] [Related]
20. Conversion of Aβ43 to Aβ40 by the successive action of angiotensin-converting enzyme 2 and angiotensin-converting enzyme.
Liu S; Liu J; Miura Y; Tanabe C; Maeda T; Terayama Y; Turner AJ; Zou K; Komano H
J Neurosci Res; 2014 Sep; 92(9):1178-86. PubMed ID: 24823497
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
