294 related articles for article (PubMed ID: 22360810)
1. Reverse TCA cycle flux through isocitrate dehydrogenases 1 and 2 is required for lipogenesis in hypoxic melanoma cells.
Filipp FV; Scott DA; Ronai ZA; Osterman AL; Smith JW
Pigment Cell Melanoma Res; 2012 May; 25(3):375-83. PubMed ID: 22360810
[TBL] [Abstract][Full Text] [Related]
2. Reductive TCA cycle metabolism fuels glutamine- and glucose-stimulated insulin secretion.
Zhang GF; Jensen MV; Gray SM; El K; Wang Y; Lu D; Becker TC; Campbell JE; Newgard CB
Cell Metab; 2021 Apr; 33(4):804-817.e5. PubMed ID: 33321098
[TBL] [Abstract][Full Text] [Related]
3. Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability.
Wise DR; Ward PS; Shay JE; Cross JR; Gruber JJ; Sachdeva UM; Platt JM; DeMatteo RG; Simon MC; Thompson CB
Proc Natl Acad Sci U S A; 2011 Dec; 108(49):19611-6. PubMed ID: 22106302
[TBL] [Abstract][Full Text] [Related]
4. Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia.
Metallo CM; Gameiro PA; Bell EL; Mattaini KR; Yang J; Hiller K; Jewell CM; Johnson ZR; Irvine DJ; Guarente L; Kelleher JK; Vander Heiden MG; Iliopoulos O; Stephanopoulos G
Nature; 2011 Nov; 481(7381):380-4. PubMed ID: 22101433
[TBL] [Abstract][Full Text] [Related]
5. Comparative metabolic flux profiling of melanoma cell lines: beyond the Warburg effect.
Scott DA; Richardson AD; Filipp FV; Knutzen CA; Chiang GG; Ronai ZA; Osterman AL; Smith JW
J Biol Chem; 2011 Dec; 286(49):42626-42634. PubMed ID: 21998308
[TBL] [Abstract][Full Text] [Related]
6. Enhancement of de novo lipogenesis by the IDH1 and IDH2-dependent reverse TCA cycle maintains the growth and angiogenic capacity of bone marrow-derived endothelial progenitor cells under hypoxia.
He Q; Yu T; Chen J; Liang J; Lin D; Yan K; Xie Z; Song Y; Chen Z
Free Radic Biol Med; 2024 Mar; 213():327-342. PubMed ID: 38281628
[TBL] [Abstract][Full Text] [Related]
7. Cofactor balance by nicotinamide nucleotide transhydrogenase (NNT) coordinates reductive carboxylation and glucose catabolism in the tricarboxylic acid (TCA) cycle.
Gameiro PA; Laviolette LA; Kelleher JK; Iliopoulos O; Stephanopoulos G
J Biol Chem; 2013 May; 288(18):12967-77. PubMed ID: 23504317
[TBL] [Abstract][Full Text] [Related]
8. Metabolic and mind shifts: from glucose to glutamine and acetate addictions in cancer.
Corbet C; Feron O
Curr Opin Clin Nutr Metab Care; 2015 Jul; 18(4):346-53. PubMed ID: 26001655
[TBL] [Abstract][Full Text] [Related]
9. Glutamine-fueled mitochondrial metabolism is decoupled from glycolysis in melanoma.
Filipp FV; Ratnikov B; De Ingeniis J; Smith JW; Osterman AL; Scott DA
Pigment Cell Melanoma Res; 2012 Nov; 25(6):732-9. PubMed ID: 22846158
[TBL] [Abstract][Full Text] [Related]
10. Fatty acid labeling from glutamine in hypoxia can be explained by isotope exchange without net reductive isocitrate dehydrogenase (IDH) flux.
Fan J; Kamphorst JJ; Rabinowitz JD; Shlomi T
J Biol Chem; 2013 Oct; 288(43):31363-9. PubMed ID: 24030823
[TBL] [Abstract][Full Text] [Related]
11. Quantifying reductive carboxylation flux of glutamine to lipid in a brown adipocyte cell line.
Yoo H; Antoniewicz MR; Stephanopoulos G; Kelleher JK
J Biol Chem; 2008 Jul; 283(30):20621-7. PubMed ID: 18364355
[TBL] [Abstract][Full Text] [Related]
12. Itaconate controls its own synthesis via feedback-inhibition of reverse TCA cycle activity at IDH2.
Heinz A; Nonnenmacher Y; Henne A; Khalil MA; Bejkollari K; Dostert C; Hosseini S; Goldmann O; He W; Palorini R; Verschueren C; Korte M; Chiaradonna F; Medina E; Brenner D; Hiller K
Biochim Biophys Acta Mol Basis Dis; 2022 Dec; 1868(12):166530. PubMed ID: 36038039
[TBL] [Abstract][Full Text] [Related]
13. FASN deficiency induces a cytosol-to-mitochondria citrate flux to mitigate detachment-induced oxidative stress.
Dai W; Wang Z; Wang G; Wang QA; DeBerardinis R; Jiang L
Cell Rep; 2023 Aug; 42(8):112971. PubMed ID: 37578864
[TBL] [Abstract][Full Text] [Related]
14. IDH2 compensates for IDH1 mutation to maintain cell survival under hypoxic conditions in IDH1‑mutant tumor cells.
Zhang Y; Lv W; Li Q; Wang Q; Ru Y; Xiong X; Yan F; Pan T; Lin W; Li X
Mol Med Rep; 2019 Aug; 20(2):1893-1900. PubMed ID: 31257503
[TBL] [Abstract][Full Text] [Related]
15. Gluconeogenic precursor availability regulates flux through the glyoxylate shunt in
Crousilles A; Dolan SK; Brear P; Chirgadze DY; Welch M
J Biol Chem; 2018 Sep; 293(37):14260-14269. PubMed ID: 30030382
[TBL] [Abstract][Full Text] [Related]
16. Two phenotypically compensating isocitrate dehydrogenases in Ralstonia eutropha.
Wang ZX; Brämer C; Steinbüchel A
FEMS Microbiol Lett; 2003 Oct; 227(1):9-16. PubMed ID: 14568142
[TBL] [Abstract][Full Text] [Related]
17. IDH1 mutations alter citric acid cycle metabolism and increase dependence on oxidative mitochondrial metabolism.
Grassian AR; Parker SJ; Davidson SM; Divakaruni AS; Green CR; Zhang X; Slocum KL; Pu M; Lin F; Vickers C; Joud-Caldwell C; Chung F; Yin H; Handly ED; Straub C; Growney JD; Vander Heiden MG; Murphy AN; Pagliarini R; Metallo CM
Cancer Res; 2014 Jun; 74(12):3317-31. PubMed ID: 24755473
[TBL] [Abstract][Full Text] [Related]
18. Knockdown of both mitochondrial isocitrate dehydrogenase enzymes in pancreatic beta cells inhibits insulin secretion.
MacDonald MJ; Brown LJ; Longacre MJ; Stoker SW; Kendrick MA; Hasan NM
Biochim Biophys Acta; 2013 Nov; 1830(11):5104-11. PubMed ID: 23876293
[TBL] [Abstract][Full Text] [Related]
19. Increased flux through the TCA cycle enhances bacitracin production by Bacillus licheniformis DW2.
Liu Z; Yu W; Nomura CT; Li J; Chen S; Yang Y; Wang Q
Appl Microbiol Biotechnol; 2018 Aug; 102(16):6935-6946. PubMed ID: 29911294
[TBL] [Abstract][Full Text] [Related]
20. Downregulation of PCK2 remodels tricarboxylic acid cycle in tumor-repopulating cells of melanoma.
Luo S; Li Y; Ma R; Liu J; Xu P; Zhang H; Tang K; Ma J; Liu N; Zhang Y; Sun Y; Ji T; Liang X; Yin X; Liu Y; Tong W; Niu Y; Wang N; Wang X; Huang B
Oncogene; 2017 Jun; 36(25):3609-3617. PubMed ID: 28166201
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
