171 related articles for article (PubMed ID: 22365751)
21. Synthesis and SAR of 5-amino- and 5-(aminomethyl)benzofuran histamine H3 receptor antagonists with improved potency.
Sun M; Zhao C; Gfesser GA; Thiffault C; Miller TR; Marsh K; Wetter J; Curtis M; Faghih R; Esbenshade TA; Hancock AA; Cowart M
J Med Chem; 2005 Oct; 48(20):6482-90. PubMed ID: 16190774
[TBL] [Abstract][Full Text] [Related]
22. Synthesis and biological evaluation of new non-imidazole H3-receptor antagonists of the 2-aminobenzimidazole series.
Rivara M; Zuliani V; Cocconcelli G; Morini G; Comini M; Rivara S; Mor M; Bordi F; Barocelli E; Ballabeni V; Bertoni S; Plazzi PV
Bioorg Med Chem; 2006 Mar; 14(5):1413-24. PubMed ID: 16263297
[TBL] [Abstract][Full Text] [Related]
23. Synthesis and evaluation of pyridazinone-phenethylamine derivatives as selective and orally bioavailable histamine H3 receptor antagonists with robust wake-promoting activity.
Dandu RR; Gruner JA; Mathiasen JR; Aimone LD; Hostetler G; Benfield C; Bendesky RJ; Marcy VR; Raddatz R; Hudkins RL
Bioorg Med Chem Lett; 2011 Nov; 21(21):6362-5. PubMed ID: 21944855
[TBL] [Abstract][Full Text] [Related]
24. Dibasic biphenyl H3 receptor antagonists: Steric tolerance for a lipophilic side chain.
Bordi F; Rivara S; Dallaturca E; Carmi C; Pala D; Lodola A; Vacondio F; Flammini L; Bertoni S; Ballabeni V; Barocelli E; Mor M
Eur J Med Chem; 2012 Feb; 48():214-30. PubMed ID: 22222138
[TBL] [Abstract][Full Text] [Related]
25. Inverse agonist histamine H3 receptor PET tracers labelled with carbon-11 or fluorine-18.
Hamill TG; Sato N; Jitsuoka M; Tokita S; Sanabria S; Eng W; Ryan C; Krause S; Takenaga N; Patel S; Zeng Z; Williams D; Sur C; Hargreaves R; Burns HD
Synapse; 2009 Dec; 63(12):1122-32. PubMed ID: 19670309
[TBL] [Abstract][Full Text] [Related]
26. Synthesis and evaluation of a spiro-isobenzofuranone class of histamine H3 receptor inverse agonists.
Jitsuoka M; Tsukahara D; Ito S; Tanaka T; Takenaga N; Tokita S; Sato N
Bioorg Med Chem Lett; 2008 Sep; 18(18):5101-6. PubMed ID: 18768318
[TBL] [Abstract][Full Text] [Related]
27. Discovery of novel spiro-piperidine derivatives as highly potent and selective melanin-concentrating hormone 1 receptor antagonists.
Suzuki T; Moriya M; Sakamoto T; Suga T; Kishino H; Takahashi H; Ishikawa M; Nagai K; Imai Y; Sekino E; Ito M; Iwaasa H; Ishihara A; Tokita S; Kanatani A; Sato N; Fukami T
Bioorg Med Chem Lett; 2009 Jun; 19(11):3072-7. PubMed ID: 19403308
[TBL] [Abstract][Full Text] [Related]
28. Sigma ligands with subnanomolar affinity and preference for the sigma 2 binding site. 2. Spiro-joined benzofuran, isobenzofuran, and benzopyran piperidines.
Moltzen EK; Perregaard J; Meier E
J Med Chem; 1995 May; 38(11):2009-17. PubMed ID: 7783132
[TBL] [Abstract][Full Text] [Related]
29. Optimization of 5-pyridazin-3-one phenoxypropylamines as potent, selective histamine H₃ receptor antagonists with potent cognition enhancing activity.
Tao M; Aimone LD; Huang Z; Mathiasen J; Raddatz R; Lyons J; Hudkins RL
J Med Chem; 2012 Jan; 55(1):414-23. PubMed ID: 22107017
[TBL] [Abstract][Full Text] [Related]
30. N-Alkenyl and cycloalkyl carbamates as dual acting histamine H3 and H4 receptor ligands.
Więcek M; Kottke T; Ligneau X; Schunack W; Seifert R; Stark H; Handzlik J; Kieć-Kononowicz K
Bioorg Med Chem; 2011 May; 19(9):2850-8. PubMed ID: 21498080
[TBL] [Abstract][Full Text] [Related]
31. Two novel and selective nonimidazole histamine H3 receptor antagonists A-304121 and A-317920: I. In vitro pharmacological effects.
Esbenshade TA; Krueger KM; Miller TR; Kang CH; Denny LI; Witte DG; Yao BB; Fox GB; Faghih R; Bennani YL; Williams M; Hancock AA
J Pharmacol Exp Ther; 2003 Jun; 305(3):887-96. PubMed ID: 12606603
[TBL] [Abstract][Full Text] [Related]
32. Synthesis and structure-activity relationships of N-aryl-piperidine derivatives as potent (partial) agonists for human histamine H3 receptor.
Ishikawa M; Furuuchi T; Yamauchi M; Yokoyama F; Kakui N; Sato Y
Bioorg Med Chem; 2010 Jul; 18(14):5441-8. PubMed ID: 20541426
[TBL] [Abstract][Full Text] [Related]
33. Design and evaluation of novel biphenyl sulfonamide derivatives with potent histamine H(3) receptor inverse agonist activity.
Covel JA; Santora VJ; Smith JM; Hayashi R; Gallardo C; Weinhouse MI; Ibarra JB; Schultz JA; Park DM; Estrada SA; Hofilena BJ; Pulley MD; Smith BM; Ren A; Suarez M; Frazer J; Edwards J; Hauser EK; Lorea J; Semple G; Grottick AJ
J Med Chem; 2009 Sep; 52(18):5603-11. PubMed ID: 19722526
[TBL] [Abstract][Full Text] [Related]
34. Synthesis, biological activity, QSAR and QSPR study of 2-aminobenzimidazole derivatives as potent H3-antagonists.
Mor M; Bordi F; Silva C; Rivara S; Zuliani V; Vacondio F; Rivara M; Barocelli E; Bertoni S; Ballabeni V; Magnanini F; Impicciatore M; Plazzi PV
Bioorg Med Chem; 2004 Feb; 12(4):663-74. PubMed ID: 14759727
[TBL] [Abstract][Full Text] [Related]
35. Development of chiral N-alkylcarbamates as new leads for potent and selective H3-receptor antagonists: synthesis, capillary electrophoresis, and in vitro and oral in vivo activity.
Sasse A; Kiec-Kononowicz K; Stark H; Motyl M; Reidemeister S; Ganellin CR; Ligneau X; Schwartz JC; Schunack W
J Med Chem; 1999 Feb; 42(4):593-600. PubMed ID: 10052966
[TBL] [Abstract][Full Text] [Related]
36. Benzylpiperidine variations on histamine H3 receptor ligands for improved drug-likeness.
Wingen K; Schwed JS; Isensee K; Weizel L; Zivković A; Odadzic D; Stark H
Bioorg Med Chem Lett; 2014 May; 24(10):2236-9. PubMed ID: 24745967
[TBL] [Abstract][Full Text] [Related]
37. Novel sigma receptor ligands. Part 2. SAR of spiro[[2]benzopyran-1,4'-piperidines] and spiro[[2]benzofuran-1,4'-piperidines] with carbon substituents in position 3.
Maier CA; Wünsch B
J Med Chem; 2002 Oct; 45(22):4923-30. PubMed ID: 12383018
[TBL] [Abstract][Full Text] [Related]
38. 4-phenoxypiperidines: potent, conformationally restricted, non-imidazole histamine H3 antagonists.
Dvorak CA; Apodaca R; Barbier AJ; Berridge CW; Wilson SJ; Boggs JD; Xiao W; Lovenberg TW; Carruthers NI
J Med Chem; 2005 Mar; 48(6):2229-38. PubMed ID: 15771465
[TBL] [Abstract][Full Text] [Related]
39. Identification and pharmacological characterization of a series of new 1H-4-substituted-imidazoyl histamine H3 receptor ligands.
Yates SL; Phillips JG; Gregory R; Pawlowski GP; Fadnis L; Khan MA; Ali SM; Tedford CE
J Pharmacol Exp Ther; 1999 May; 289(2):1151-9. PubMed ID: 10215699
[TBL] [Abstract][Full Text] [Related]
40. Synthesis and structure-activity relationship of 5-pyridazin-3-one phenoxypiperidines as potent, selective histamine H(3) receptor inverse agonists.
Tao M; Aimone LD; Gruner JA; Mathiasen JR; Huang Z; Lyons J; Raddatz R; Hudkins RL
Bioorg Med Chem Lett; 2012 Jan; 22(2):1073-7. PubMed ID: 22197136
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
