BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

406 related articles for article (PubMed ID: 22365830)

  • 1. Regulation of DNA-end resection by hnRNPU-like proteins promotes DNA double-strand break signaling and repair.
    Polo SE; Blackford AN; Chapman JR; Baskcomb L; Gravel S; Rusch A; Thomas A; Blundred R; Smith P; Kzhyshkowska J; Dobner T; Taylor AM; Turnell AS; Stewart GS; Grand RJ; Jackson SP
    Mol Cell; 2012 Feb; 45(4):505-16. PubMed ID: 22365830
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cell cycle-dependent complex formation of BRCA1.CtIP.MRN is important for DNA double-strand break repair.
    Chen L; Nievera CJ; Lee AY; Wu X
    J Biol Chem; 2008 Mar; 283(12):7713-20. PubMed ID: 18171670
    [TBL] [Abstract][Full Text] [Related]  

  • 3. MRE11-RAD50-NBS1 complex dictates DNA repair independent of H2AX.
    Yuan J; Chen J
    J Biol Chem; 2010 Jan; 285(2):1097-104. PubMed ID: 19910469
    [TBL] [Abstract][Full Text] [Related]  

  • 4. N terminus of CtIP is critical for homologous recombination-mediated double-strand break repair.
    Yuan J; Chen J
    J Biol Chem; 2009 Nov; 284(46):31746-52. PubMed ID: 19759395
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Deubiquitylating Enzyme USP4 Cooperates with CtIP in DNA Double-Strand Break End Resection.
    Liu H; Zhang H; Wang X; Tian Q; Hu Z; Peng C; Jiang P; Wang T; Guo W; Chen Y; Li X; Zhang P; Pei H
    Cell Rep; 2015 Oct; 13(1):93-107. PubMed ID: 26387952
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The MRE11 complex: A versatile toolkit for the repair of broken DNA.
    Reginato G; Cejka P
    DNA Repair (Amst); 2020; 91-92():102869. PubMed ID: 32480356
    [TBL] [Abstract][Full Text] [Related]  

  • 7. ATP puts the brake on DNA double-strand break repair: a new study shows that ATP switches the Mre11-Rad50-Nbs1 repair factor between signaling and processing of DNA ends.
    Hopfner KP
    Bioessays; 2014 Dec; 36(12):1170-8. PubMed ID: 25213441
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template.
    Williams RS; Williams JS; Tainer JA
    Biochem Cell Biol; 2007 Aug; 85(4):509-20. PubMed ID: 17713585
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Stable maintenance of the Mre11-Rad50-Nbs1 complex is sufficient to restore the DNA double-strand break response in cells lacking RecQL4 helicase activity.
    Kim H; Choi H; Im JS; Park SY; Shin G; Yoo JH; Kim G; Lee JK
    J Biol Chem; 2021 Oct; 297(4):101148. PubMed ID: 34473993
    [TBL] [Abstract][Full Text] [Related]  

  • 10. MRNIP condensates promote DNA double-strand break sensing and end resection.
    Wang YL; Zhao WW; Bai SM; Feng LL; Bie SY; Gong L; Wang F; Wei MB; Feng WX; Pang XL; Qin CL; Yin XK; Wang YN; Zhou W; Wahl DR; Liu Q; Chen M; Hung MC; Wan XB
    Nat Commun; 2022 May; 13(1):2638. PubMed ID: 35551189
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The role of the Mre11-Rad50-Nbs1 complex in double-strand break repair-facts and myths.
    Takeda S; Hoa NN; Sasanuma H
    J Radiat Res; 2016 Aug; 57 Suppl 1(Suppl 1):i25-i32. PubMed ID: 27311583
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Deubiquitinase USP2 stabilizes the MRE11-RAD50-NBS1 complex at DNA double-strand break sites by counteracting the ubiquitination of NBS1.
    Kim H; Kim D; Choi H; Shin G; Lee JK
    J Biol Chem; 2023 Jan; 299(1):102752. PubMed ID: 36436562
    [TBL] [Abstract][Full Text] [Related]  

  • 13. USP4 Auto-Deubiquitylation Promotes Homologous Recombination.
    Wijnhoven P; Konietzny R; Blackford AN; Travers J; Kessler BM; Nishi R; Jackson SP
    Mol Cell; 2015 Nov; 60(3):362-73. PubMed ID: 26455393
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Human CtIP promotes DNA end resection.
    Sartori AA; Lukas C; Coates J; Mistrik M; Fu S; Bartek J; Baer R; Lukas J; Jackson SP
    Nature; 2007 Nov; 450(7169):509-14. PubMed ID: 17965729
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Rad17 recruits the MRE11-RAD50-NBS1 complex to regulate the cellular response to DNA double-strand breaks.
    Wang Q; Goldstein M; Alexander P; Wakeman TP; Sun T; Feng J; Lou Z; Kastan MB; Wang XF
    EMBO J; 2014 Apr; 33(8):862-77. PubMed ID: 24534091
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells.
    Truong LN; Li Y; Shi LZ; Hwang PY; He J; Wang H; Razavian N; Berns MW; Wu X
    Proc Natl Acad Sci U S A; 2013 May; 110(19):7720-5. PubMed ID: 23610439
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Phosphorylated CtIP Functions as a Co-factor of the MRE11-RAD50-NBS1 Endonuclease in DNA End Resection.
    Anand R; Ranjha L; Cannavo E; Cejka P
    Mol Cell; 2016 Dec; 64(5):940-950. PubMed ID: 27889449
    [TBL] [Abstract][Full Text] [Related]  

  • 18. MRN-dependent and independent pathways for recruitment of TOPBP1 to DNA double-strand breaks.
    Montales K; Ruis K; Lindsay H; Michael WM
    PLoS One; 2022; 17(8):e0271905. PubMed ID: 35917319
    [TBL] [Abstract][Full Text] [Related]  

  • 19. NBS1 promotes the endonuclease activity of the MRE11-RAD50 complex by sensing CtIP phosphorylation.
    Anand R; Jasrotia A; Bundschuh D; Howard SM; Ranjha L; Stucki M; Cejka P
    EMBO J; 2019 Apr; 38(7):. PubMed ID: 30787182
    [TBL] [Abstract][Full Text] [Related]  

  • 20. CtIP maintains stability at common fragile sites and inverted repeats by end resection-independent endonuclease activity.
    Wang H; Li Y; Truong LN; Shi LZ; Hwang PY; He J; Do J; Cho MJ; Li H; Negrete A; Shiloach J; Berns MW; Shen B; Chen L; Wu X
    Mol Cell; 2014 Jun; 54(6):1012-1021. PubMed ID: 24837675
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.