261 related articles for article (PubMed ID: 22366949)
1. Reverse engineering of TLX oncogenic transcriptional networks identifies RUNX1 as tumor suppressor in T-ALL.
Della Gatta G; Palomero T; Perez-Garcia A; Ambesi-Impiombato A; Bansal M; Carpenter ZW; De Keersmaecker K; Sole X; Xu L; Paietta E; Racevskis J; Wiernik PH; Rowe JM; Meijerink JP; Califano A; Ferrando AA
Nat Med; 2012 Feb; 18(3):436-40. PubMed ID: 22366949
[TBL] [Abstract][Full Text] [Related]
2. RUNX1 is required for oncogenic
Choi A; Illendula A; Pulikkan JA; Roderick JE; Tesell J; Yu J; Hermance N; Zhu LJ; Castilla LH; Bushweller JH; Kelliher MA
Blood; 2017 Oct; 130(15):1722-1733. PubMed ID: 28790107
[TBL] [Abstract][Full Text] [Related]
3. TLX homeodomain oncogenes mediate T cell maturation arrest in T-ALL via interaction with ETS1 and suppression of TCRα gene expression.
Dadi S; Le Noir S; Payet-Bornet D; Lhermitte L; Zacarias-Cabeza J; Bergeron J; Villarèse P; Vachez E; Dik WA; Millien C; Radford I; Verhoeyen E; Cosset FL; Petit A; Ifrah N; Dombret H; Hermine O; Spicuglia S; Langerak AW; Macintyre EA; Nadel B; Ferrier P; Asnafi V
Cancer Cell; 2012 Apr; 21(4):563-76. PubMed ID: 22516263
[TBL] [Abstract][Full Text] [Related]
4. The TLX1 oncogene drives aneuploidy in T cell transformation.
De Keersmaecker K; Real PJ; Gatta GD; Palomero T; Sulis ML; Tosello V; Van Vlierberghe P; Barnes K; Castillo M; Sole X; Hadler M; Lenz J; Aplan PD; Kelliher M; Kee BL; Pandolfi PP; Kappes D; Gounari F; Petrie H; Van der Meulen J; Speleman F; Paietta E; Racevskis J; Wiernik PH; Rowe JM; Soulier J; Avran D; Cavé H; Dastugue N; Raimondi S; Meijerink JP; Cordon-Cardo C; Califano A; Ferrando AA
Nat Med; 2010 Nov; 16(11):1321-7. PubMed ID: 20972433
[TBL] [Abstract][Full Text] [Related]
5. Characterization of the genome-wide TLX1 binding profile in T-cell acute lymphoblastic leukemia.
Durinck K; Van Loocke W; Van der Meulen J; Van de Walle I; Ongenaert M; Rondou P; Wallaert A; de Bock CE; Van Roy N; Poppe B; Cools J; Soulier J; Taghon T; Speleman F; Van Vlierberghe P
Leukemia; 2015 Dec; 29(12):2317-27. PubMed ID: 26108691
[TBL] [Abstract][Full Text] [Related]
6. Cooperative Enhancer Activation by TLX1 and STAT5 Drives Development of NUP214-ABL1/TLX1-Positive T Cell Acute Lymphoblastic Leukemia.
Vanden Bempt M; Demeyer S; Broux M; De Bie J; Bornschein S; Mentens N; Vandepoel R; Geerdens E; Radaelli E; Bornhauser BC; Kulozik AE; Meijerink JP; Bourquin JP; de Bock CE; Cools J
Cancer Cell; 2018 Aug; 34(2):271-285.e7. PubMed ID: 30107177
[TBL] [Abstract][Full Text] [Related]
7. MEIS proteins as partners of the TLX1/HOX11 oncoprotein.
Milech N; Gottardo NG; Ford J; D'Souza D; Greene WK; Kees UR; Watt PM
Leuk Res; 2010 Mar; 34(3):358-63. PubMed ID: 19559479
[TBL] [Abstract][Full Text] [Related]
8. PHF6 mutations in T-cell acute lymphoblastic leukemia.
Van Vlierberghe P; Palomero T; Khiabanian H; Van der Meulen J; Castillo M; Van Roy N; De Moerloose B; Philippé J; González-García S; Toribio ML; Taghon T; Zuurbier L; Cauwelier B; Harrison CJ; Schwab C; Pisecker M; Strehl S; Langerak AW; Gecz J; Sonneveld E; Pieters R; Paietta E; Rowe JM; Wiernik PH; Benoit Y; Soulier J; Poppe B; Yao X; Cordon-Cardo C; Meijerink J; Rabadan R; Speleman F; Ferrando A
Nat Genet; 2010 Apr; 42(4):338-42. PubMed ID: 20228800
[TBL] [Abstract][Full Text] [Related]
9. Core transcriptional regulatory circuit controlled by the TAL1 complex in human T cell acute lymphoblastic leukemia.
Sanda T; Lawton LN; Barrasa MI; Fan ZP; Kohlhammer H; Gutierrez A; Ma W; Tatarek J; Ahn Y; Kelliher MA; Jamieson CH; Staudt LM; Young RA; Look AT
Cancer Cell; 2012 Aug; 22(2):209-21. PubMed ID: 22897851
[TBL] [Abstract][Full Text] [Related]
10. TLX1 and NOTCH coregulate transcription in T cell acute lymphoblastic leukemia cells.
Riz I; Hawley TS; Luu TV; Lee NH; Hawley RG
Mol Cancer; 2010 Jul; 9():181. PubMed ID: 20618946
[TBL] [Abstract][Full Text] [Related]
11. TLX1-induced T-cell acute lymphoblastic leukemia.
De Keersmaecker K; Ferrando AA
Clin Cancer Res; 2011 Oct; 17(20):6381-6. PubMed ID: 21705452
[TBL] [Abstract][Full Text] [Related]
12. Transforming potential of the T-cell acute lymphoblastic leukemia-associated homeobox genes HOXA13, TLX1, and TLX3.
Su X; Drabkin H; Clappier E; Morgado E; Busson M; Romana S; Soulier J; Berger R; Bernard OA; Lavau C
Genes Chromosomes Cancer; 2006 Sep; 45(9):846-55. PubMed ID: 16804919
[TBL] [Abstract][Full Text] [Related]
13. Hematopoietic immortalizing function of the NKL-subclass homeobox gene TLX1.
Zweier-Renn LA; Hawley TS; Burkett S; Ramezani A; Riz I; Adler RL; Hickstein DD; Hawley RG
Genes Chromosomes Cancer; 2010 Feb; 49(2):119-31. PubMed ID: 19862821
[TBL] [Abstract][Full Text] [Related]
14. RUNX1 promotes cell growth in human T-cell acute lymphoblastic leukemia by transcriptional regulation of key target genes.
Jenkins CE; Gusscott S; Wong RJ; Shevchuk OO; Rana G; Giambra V; Tyshchenko K; Islam R; Hirst M; Weng AP
Exp Hematol; 2018 Aug; 64():84-96. PubMed ID: 29733873
[TBL] [Abstract][Full Text] [Related]
15. Novel insights on TLX1 function in T-ALL pave the way towards differentiation therapy.
De Keersmaecker K
Haematologica; 2012 Jun; 97(6):795. PubMed ID: 22665526
[No Abstract] [Full Text] [Related]
16. NKL homeobox gene activities in hematopoietic stem cells, T-cell development and T-cell leukemia.
Nagel S; Pommerenke C; Scherr M; Meyer C; Kaufmann M; Battmer K; MacLeod RA; Drexler HG
PLoS One; 2017; 12(2):e0171164. PubMed ID: 28151996
[TBL] [Abstract][Full Text] [Related]
17. Activation of TLX3 and NKX2-5 in t(5;14)(q35;q32) T-cell acute lymphoblastic leukemia by remote 3'-BCL11B enhancers and coregulation by PU.1 and HMGA1.
Nagel S; Scherr M; Kel A; Hornischer K; Crawford GE; Kaufmann M; Meyer C; Drexler HG; MacLeod RA
Cancer Res; 2007 Feb; 67(4):1461-71. PubMed ID: 17308084
[TBL] [Abstract][Full Text] [Related]
18. Epigenetic Silencing Affects l-Asparaginase Sensitivity and Predicts Outcome in T-ALL.
Touzart A; Lengliné E; Latiri M; Belhocine M; Smith C; Thomas X; Spicuglia S; Puthier D; Pflumio F; Leguay T; Graux C; Chalandon Y; Huguet F; Leprêtre S; Ifrah N; Dombret H; Macintyre E; Hunault M; Boissel N; Asnafi V
Clin Cancer Res; 2019 Apr; 25(8):2483-2493. PubMed ID: 30659025
[TBL] [Abstract][Full Text] [Related]
19. TLX1/HOX11-mediated disruption of primary thymocyte differentiation prior to the CD4+CD8+ double-positive stage.
Owens BM; Hawley TS; Spain LM; Kerkel KA; Hawley RG
Br J Haematol; 2006 Jan; 132(2):216-29. PubMed ID: 16398656
[TBL] [Abstract][Full Text] [Related]
20. Role of TLX1 in T-cell acute lymphoblastic leukaemia pathogenesis.
Riz I; Hawley TS; Johnston H; Hawley RG
Br J Haematol; 2009 Apr; 145(1):140-3. PubMed ID: 19133982
[No Abstract] [Full Text] [Related]
[Next] [New Search]
