BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

216 related articles for article (PubMed ID: 22369852)

  • 1. Celastrol suppresses growth and induces apoptosis of human hepatocellular carcinoma through the modulation of STAT3/JAK2 signaling cascade in vitro and in vivo.
    Rajendran P; Li F; Shanmugam MK; Kannaiyan R; Goh JN; Wong KF; Wang W; Khin E; Tergaonkar V; Kumar AP; Luk JM; Sethi G
    Cancer Prev Res (Phila); 2012 Apr; 5(4):631-43. PubMed ID: 22369852
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Suppression of signal transducer and activator of transcription 3 activation by butein inhibits growth of human hepatocellular carcinoma in vivo.
    Rajendran P; Ong TH; Chen L; Li F; Shanmugam MK; Vali S; Abbasi T; Kapoor S; Sharma A; Kumar AP; Hui KM; Sethi G
    Clin Cancer Res; 2011 Mar; 17(6):1425-39. PubMed ID: 21131551
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3.
    Subramaniam A; Shanmugam MK; Ong TH; Li F; Perumal E; Chen L; Vali S; Abbasi T; Kapoor S; Ahn KS; Kumar AP; Hui KM; Sethi G
    Br J Pharmacol; 2013 Oct; 170(4):807-21. PubMed ID: 23848338
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Honokiol inhibits signal transducer and activator of transcription-3 signaling, proliferation, and survival of hepatocellular carcinoma cells via the protein tyrosine phosphatase SHP-1.
    Rajendran P; Li F; Shanmugam MK; Vali S; Abbasi T; Kapoor S; Ahn KS; Kumar AP; Sethi G
    J Cell Physiol; 2012 May; 227(5):2184-95. PubMed ID: 21792937
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Abrogation of STAT3 signaling cascade by zerumbone inhibits proliferation and induces apoptosis in renal cell carcinoma xenograft mouse model.
    Shanmugam MK; Rajendran P; Li F; Kim C; Sikka S; Siveen KS; Kumar AP; Ahn KS; Sethi G
    Mol Carcinog; 2015 Oct; 54(10):971-85. PubMed ID: 24797723
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of beta-escin as a novel inhibitor of signal transducer and activator of transcription 3/Janus-activated kinase 2 signaling pathway that suppresses proliferation and induces apoptosis in human hepatocellular carcinoma cells.
    Tan SM; Li F; Rajendran P; Kumar AP; Hui KM; Sethi G
    J Pharmacol Exp Ther; 2010 Jul; 334(1):285-93. PubMed ID: 20378717
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Evodiamine inhibits STAT3 signaling by inducing phosphatase shatterproof 1 in hepatocellular carcinoma cells.
    Yang J; Cai X; Lu W; Hu C; Xu X; Yu Q; Cao P
    Cancer Lett; 2013 Jan; 328(2):243-51. PubMed ID: 23032719
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Anticancer activity of dietary xanthone α-mangostin against hepatocellular carcinoma by inhibition of STAT3 signaling via stabilization of SHP1.
    Zhang H; Tan YP; Zhao L; Wang L; Fu NJ; Zheng SP; Shen XF
    Cell Death Dis; 2020 Jan; 11(1):63. PubMed ID: 31980595
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Farnesol inhibits tumor growth and enhances the anticancer effects of bortezomib in multiple myeloma xenograft mouse model through the modulation of STAT3 signaling pathway.
    Lee JH; Kim C; Kim SH; Sethi G; Ahn KS
    Cancer Lett; 2015 May; 360(2):280-93. PubMed ID: 25697480
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of STAT3 dimerization and acetylation by garcinol suppresses the growth of human hepatocellular carcinoma in vitro and in vivo.
    Sethi G; Chatterjee S; Rajendran P; Li F; Shanmugam MK; Wong KF; Kumar AP; Senapati P; Behera AK; Hui KM; Basha J; Natesh N; Luk JM; Kundu TK
    Mol Cancer; 2014 Mar; 13():66. PubMed ID: 24655440
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A novel anti-cancer agent Icaritin suppresses hepatocellular carcinoma initiation and malignant growth through the IL-6/Jak2/Stat3 pathway.
    Zhao H; Guo Y; Li S; Han R; Ying J; Zhu H; Wang Y; Yin L; Han Y; Sun L; Wang Z; Lin Q; Bi X; Jiao Y; Jia H; Zhao J; Huang Z; Li Z; Zhou J; Song W; Meng K; Cai J
    Oncotarget; 2015 Oct; 6(31):31927-43. PubMed ID: 26376676
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Development of a novel azaspirane that targets the Janus kinase-signal transducer and activator of transcription (STAT) pathway in hepatocellular carcinoma in vitro and in vivo.
    Mohan CD; Bharathkumar H; Bulusu KC; Pandey V; Rangappa S; Fuchs JE; Shanmugam MK; Dai X; Li F; Deivasigamani A; Hui KM; Kumar AP; Lobie PE; Bender A; Basappa ; Sethi G; Rangappa KS
    J Biol Chem; 2014 Dec; 289(49):34296-307. PubMed ID: 25320076
    [TBL] [Abstract][Full Text] [Related]  

  • 13. ZnAs@SiO
    Huang Y; Zhou B; Luo H; Mao J; Huang Y; Zhang K; Mei C; Yan Y; Jin H; Gao J; Su Z; Pang P; Li D; Shan H
    Theranostics; 2019; 9(15):4391-4408. PubMed ID: 31285768
    [No Abstract]   [Full Text] [Related]  

  • 14. γ-Tocotrienol is a novel inhibitor of constitutive and inducible STAT3 signalling pathway in human hepatocellular carcinoma: potential role as an antiproliferative, pro-apoptotic and chemosensitizing agent.
    Rajendran P; Li F; Manu KA; Shanmugam MK; Loo SY; Kumar AP; Sethi G
    Br J Pharmacol; 2011 May; 163(2):283-98. PubMed ID: 21198544
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Negative regulation of signal transducer and activator of transcription-3 signalling cascade by lupeol inhibits growth and induces apoptosis in hepatocellular carcinoma cells.
    Siveen KS; Nguyen AH; Lee JH; Li F; Singh SS; Kumar AP; Low G; Jha S; Tergaonkar V; Ahn KS; Sethi G
    Br J Cancer; 2014 Sep; 111(7):1327-37. PubMed ID: 25101566
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ascochlorin, an isoprenoid antibiotic inhibits growth and invasion of hepatocellular carcinoma by targeting STAT3 signaling cascade through the induction of PIAS3.
    Dai X; Ahn KS; Kim C; Siveen KS; Ong TH; Shanmugam MK; Li F; Shi J; Kumar AP; Wang LZ; Goh BC; Magae J; Hui KM; Sethi G
    Mol Oncol; 2015 Apr; 9(4):818-33. PubMed ID: 25624051
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Thymoquinone inhibits proliferation, induces apoptosis and chemosensitizes human multiple myeloma cells through suppression of signal transducer and activator of transcription 3 activation pathway.
    Li F; Rajendran P; Sethi G
    Br J Pharmacol; 2010 Oct; 161(3):541-54. PubMed ID: 20880395
    [TBL] [Abstract][Full Text] [Related]  

  • 18. (-)-Oleocanthal inhibits growth and metastasis by blocking activation of STAT3 in human hepatocellular carcinoma.
    Pei T; Meng Q; Han J; Sun H; Li L; Song R; Sun B; Pan S; Liang D; Liu L
    Oncotarget; 2016 Jul; 7(28):43475-43491. PubMed ID: 27259268
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A pumpkin polysaccharide induces apoptosis by inhibiting the JAK2/STAT3 pathway in human hepatoma HepG2 cells.
    Shen W; Chen C; Guan Y; Song X; Jin Y; Wang J; Hu Y; Xin T; Jiang Q; Zhong L
    Int J Biol Macromol; 2017 Nov; 104(Pt A):681-686. PubMed ID: 28634059
    [TBL] [Abstract][Full Text] [Related]  

  • 20. β-Caryophyllene oxide inhibits constitutive and inducible STAT3 signaling pathway through induction of the SHP-1 protein tyrosine phosphatase.
    Kim C; Cho SK; Kapoor S; Kumar A; Vali S; Abbasi T; Kim SH; Sethi G; Ahn KS
    Mol Carcinog; 2014 Oct; 53(10):793-806. PubMed ID: 23765383
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.