164 related articles for article (PubMed ID: 22369862)
1. Hydroxyl may not be indispensable for raltegravir: Design, synthesis and SAR Studies of raltegravir derivatives as HIV-1 inhibitors.
Wang Z; Wang M; Yao X; Li Y; Qiao W; Geng Y; Liu Y; Wang Q
Eur J Med Chem; 2012 Apr; 50():361-9. PubMed ID: 22369862
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and evaluation of N-aryl pyrrolidinones as novel anti-HIV-1 agents. Part 1.
Wu B; Kuhen K; Ngoc Nguyen T; Ellis D; Anaclerio B; He X; Yang K; Karanewsky D; Yin H; Wolff K; Bieza K; Caldwell J; He Y
Bioorg Med Chem Lett; 2006 Jul; 16(13):3430-3. PubMed ID: 16632349
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and biological evaluation of novel 2-(substituted phenylaminocarbonylmethylthio)-6-(2,6-dichlorobenzyl)-pyrimidin-4(3H)-ones as potent HIV-1 NNRTIs.
Yu M; Liu X; Li Z; Liu S; Pannecouque C; Clercq ED
Bioorg Med Chem; 2009 Nov; 17(22):7749-54. PubMed ID: 19819705
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and biological evaluation of novel 5-alkyl-2-arylthio-6-((3,4-dihydroquinolin-1(2H)-yl)methyl)pyrimidin-4(3H)-ones as potent non-nucleoside HIV-1 reverse transcriptase inhibitors.
Zhang J; Zhan P; Wu J; Li Z; Jiang Y; Ge W; Pannecouque C; De Clercq E; Liu X
Bioorg Med Chem; 2011 Jul; 19(14):4366-76. PubMed ID: 21683601
[TBL] [Abstract][Full Text] [Related]
5. Design and synthesis of 2-(2,6-dibromophenyl)-3-heteroaryl-1,3-thiazolidin-4-ones as anti-HIV agents.
Rawal RK; Tripathi R; Katti SB; Pannecouque C; De Clercq E
Eur J Med Chem; 2008 Dec; 43(12):2800-6. PubMed ID: 18242784
[TBL] [Abstract][Full Text] [Related]
6. Nonnucleoside HIV-1 reverse transcriptase inhibitors; part 3. Synthesis and antiviral activity of 5-alkyl-2-[(aryl and alkyloxyl-carbonylmethyl)thio]-6-(1-naphthylmethyl) pyrimidin-4(3H)-ones.
He Y; Chen F; Yu X; Wang Y; De Clercq E; Balzarini J; Pannecouque C
Bioorg Chem; 2004 Dec; 32(6):536-48. PubMed ID: 15530994
[TBL] [Abstract][Full Text] [Related]
7. The anti-HIV activity of three 2-alkylsulfanyl-6-benzyl-3, 4-dihydropyrimidin-4 (3H)-one derivatives acting as non-nucleoside reverse transcriptase inhibitor in vitro.
Long J; Zhang DH; Zhang GH; Rao ZK; Wang YH; Tam SC; He YP; Zheng YT
Yao Xue Xue Bao; 2010 Feb; 45(2):228-34. PubMed ID: 21348416
[TBL] [Abstract][Full Text] [Related]
8. 1,2,3-Thiadiazole thioacetanilides as a novel class of potent HIV-1 non-nucleoside reverse transcriptase inhibitors.
Zhan P; Liu X; Cao Y; Wang Y; Pannecouque C; De Clercq E
Bioorg Med Chem Lett; 2008 Oct; 18(20):5368-71. PubMed ID: 18824350
[TBL] [Abstract][Full Text] [Related]
9. Non-nucleoside HIV reverse transcriptase inhibitors, Part 6[1]: synthesis and anti-HIV activity of novel 2-[(arylcarbonylmethyl)thio]-6-arylthio DABO analogues.
Sun GF; Kuang YY; Chen FE; De Clercq E; Balzarini J; Pannecouque C
Arch Pharm (Weinheim); 2005 Oct; 338(10):457-61. PubMed ID: 16211654
[TBL] [Abstract][Full Text] [Related]
10. The design and synthesis of diaryl ether second generation HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) with enhanced potency versus key clinical mutations.
Tucker TJ; Saggar S; Sisko JT; Tynebor RM; Williams TM; Felock PJ; Flynn JA; Lai MT; Liang Y; McGaughey G; Liu M; Miller M; Moyer G; Munshi V; Perlow-Poehnelt R; Prasad S; Sanchez R; Torrent M; Vacca JP; Wan BL; Yan Y
Bioorg Med Chem Lett; 2008 May; 18(9):2959-66. PubMed ID: 18396399
[TBL] [Abstract][Full Text] [Related]
11. Arylazolylthioacetanilide. Part 8: Design, synthesis and biological evaluation of novel 2-(2-(2,4-dichlorophenyl)-2H-1,2,4-triazol-3-ylthio)-N-arylacetamides as potent HIV-1 inhibitors.
Zhan P; Chen X; Li X; Li D; Tian Y; Chen W; Pannecouque C; De Clercq E; Liu X
Eur J Med Chem; 2011 Oct; 46(10):5039-45. PubMed ID: 21872971
[TBL] [Abstract][Full Text] [Related]
12. Non-nucleoside HIV-1 reverse-transcriptase inhibitors. Part 10. Synthesis and anti-HIV activity of 5-alkyl-6-(1-naphthylmethyl)pyrimidin-4(3H)-ones with a mono- or disubstituted 2-amino function as novel 'dihydro-alkoxy-benzyl-oxopyrimidine' (DABO) analogues.
Wang Y; Chen FE; Balzarini J; De Clercq E; Pannecouque C
Chem Biodivers; 2008 Jan; 5(1):168-76. PubMed ID: 18205120
[TBL] [Abstract][Full Text] [Related]
13. Parallel solution-phase and microwave-assisted synthesis of new S-DABO derivatives endowed with subnanomolar anti-HIV-1 activity.
Manetti F; Esté JA; Clotet-Codina I; Armand-Ugón M; Maga G; Crespan E; Cancio R; Mugnaini C; Bernardini C; Togninelli A; Carmi C; Alongi M; Petricci E; Massa S; Corelli F; Botta M
J Med Chem; 2005 Dec; 48(25):8000-8. PubMed ID: 16335924
[TBL] [Abstract][Full Text] [Related]
14. Abasic analogues of TSAO-T as the first sugar derivatives that specifically inhibit HIV-1 reverse transcriptase.
Velázquez S; Chamorro C; Pérez-Pérez MJ; Alvarez R; Jimeno ML; Martín-Domenech A; Pérez C; Gago F; De Clercq E; Balzarini J; San-Félix A; Camarasa MJ
J Med Chem; 1998 Nov; 41(23):4636-47. PubMed ID: 9804703
[TBL] [Abstract][Full Text] [Related]
15. 1,2,3-Selenadiazole thioacetanilides: synthesis and anti-HIV activity evaluation.
Zhan P; Liu X; Fang Z; Pannecouque C; De Clercq E
Bioorg Med Chem; 2009 Sep; 17(17):6374-9. PubMed ID: 19647440
[TBL] [Abstract][Full Text] [Related]
16. 1,2,3-thiadiazole thioacetanilides. Part 2: Synthesis and biological evaluation of a new series of 2-{[4-(3,4-dichlorophenyl)-1,2,3-thiadiazol-5-yl]sulfanyl}acetanilides as HIV-1 inhibitors.
Zhan P; Liu XY; Li ZY; Fang ZJ; Pannecouque C; De Clercq E
Chem Biodivers; 2010 Jul; 7(7):1717-27. PubMed ID: 20658659
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and biological evaluation of novel C5 halogen-functionalized S-DABO as potent HIV-1 non-nucleoside reverse transcriptase inhibitors.
Qin H; Liu C; Guo Y; Wang R; Zhang J; Ma L; Zhang Z; Wang X; Cui Y; Liu J
Bioorg Med Chem; 2010 May; 18(9):3231-7. PubMed ID: 20371182
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and biological activity of naphthyl-substituted (B-ring) benzophenone derivatives as novel non-nucleoside HIV-1 reverse transcriptase inhibitors.
Ma XD; Zhang X; Dai HF; Yang SQ; Yang LM; Gu SX; Zheng YT; He QQ; Chen FE
Bioorg Med Chem; 2011 Aug; 19(15):4601-7. PubMed ID: 21719299
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and anti-HIV-1 activity evaluation of 5-alkyl-2-alkylthio-6-(arylcarbonyl or alpha-cyanoarylmethyl)-3,4-dihydropyrimidin-4(3H)-ones as novel non-nucleoside HIV-1 reverse transcriptase inhibitors.
Ji L; Chen FE; De Clercq E; Balzarini J; Pannecouque C
J Med Chem; 2007 Apr; 50(8):1778-86. PubMed ID: 17381078
[TBL] [Abstract][Full Text] [Related]
20. Discovery of 3,4-dihydropyrimidin-2(1H)-ones with inhibitory activity against HIV-1 replication.
Kim J; Park C; Ok T; So W; Jo M; Seo M; Kim Y; Sohn JH; Park Y; Ju MK; Kim J; Han SJ; Kim TH; Cechetto J; Nam J; Sommer P; No Z
Bioorg Med Chem Lett; 2012 Mar; 22(5):2119-24. PubMed ID: 22305583
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]