151 related articles for article (PubMed ID: 22370342)
1. The synthesis of ethacrynic acid thiazole derivatives as glutathione S-transferase pi inhibitors.
Li T; Liu G; Li H; Yang X; Jing Y; Zhao G
Bioorg Med Chem; 2012 Apr; 20(7):2316-22. PubMed ID: 22370342
[TBL] [Abstract][Full Text] [Related]
2. The synthesis of alpha,beta-unsaturated carbonyl derivatives with the ability to inhibit both glutathione S-transferase P1-1 activity and the proliferation of leukemia cells.
Zhao G; Liu C; Wang R; Song D; Wang X; Lou H; Jing Y
Bioorg Med Chem; 2007 Apr; 15(7):2701-7. PubMed ID: 17287120
[TBL] [Abstract][Full Text] [Related]
3. Novel oxadiazole analogues derived from ethacrynic acid: design, synthesis, and structure-activity relationships in inhibiting the activity of glutathione S-transferase P1-1 and cancer cell proliferation.
Yang X; Liu G; Li H; Zhang Y; Song D; Li C; Wang R; Liu B; Liang W; Jing Y; Zhao G
J Med Chem; 2010 Feb; 53(3):1015-22. PubMed ID: 20055416
[TBL] [Abstract][Full Text] [Related]
4. Peptide-bond modified glutathione conjugate analogs modulate GSTpi function in GSH-conjugation, drug sensitivity and JNK signaling.
Burg D; Riepsaame J; Pont C; Mulder G; van de Water B
Biochem Pharmacol; 2006 Jan; 71(3):268-77. PubMed ID: 16337611
[TBL] [Abstract][Full Text] [Related]
5. Ethacrynic acid butyl-ester induces apoptosis in leukemia cells through a hydrogen peroxide mediated pathway independent of glutathione S-transferase P1-1 inhibition.
Wang R; Li C; Song D; Zhao G; Zhao L; Jing Y
Cancer Res; 2007 Aug; 67(16):7856-64. PubMed ID: 17699792
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and structure-activity relationship of ethacrynic acid analogues on glutathione-s-transferase P1-1 activity inhibition.
Zhao G; Yu T; Wang R; Wang X; Jing Y
Bioorg Med Chem; 2005 Jun; 13(12):4056-62. PubMed ID: 15911318
[TBL] [Abstract][Full Text] [Related]
7. Potent anti-proliferative actions of a non-diuretic glucosamine derivative of ethacrynic acid.
Punganuru SR; Mostofa AGM; Madala HR; Basak D; Srivenugopal KS
Bioorg Med Chem Lett; 2016 Jun; 26(12):2829-2833. PubMed ID: 27156773
[TBL] [Abstract][Full Text] [Related]
8. In Vitro Inhibition of Human Placental Glutathione S-Transferase by 3-Arylcoumarin Derivatives.
Alparslan MM; Danış Ö
Arch Pharm (Weinheim); 2015 Sep; 348(9):635-42. PubMed ID: 26205366
[TBL] [Abstract][Full Text] [Related]
9. Solid phase combinatorial synthesis of benzothiazoles and evaluation of topoisomerase II inhibitory activity.
Choi SJ; Park HJ; Lee SK; Kim SW; Han G; Choo HY
Bioorg Med Chem; 2006 Feb; 14(4):1229-35. PubMed ID: 16242334
[TBL] [Abstract][Full Text] [Related]
10. Studies of glutathione transferase P1-1 bound to a platinum(IV)-based anticancer compound reveal the molecular basis of its activation.
Parker LJ; Italiano LC; Morton CJ; Hancock NC; Ascher DB; Aitken JB; Harris HH; Campomanes P; Rothlisberger U; De Luca A; Lo Bello M; Ang WH; Dyson PJ; Parker MW
Chemistry; 2011 Jul; 17(28):7806-16. PubMed ID: 21681839
[TBL] [Abstract][Full Text] [Related]
11. A novel class of ethacrynic acid derivatives as promising drug-like potent generation of anticancer agents with established mechanism of action.
Mignani S; El Brahmi N; El Kazzouli S; Eloy L; Courilleau D; Caron J; Bousmina MM; Caminade AM; Cresteil T; Majoral JP
Eur J Med Chem; 2016 Oct; 122():656-673. PubMed ID: 27448922
[TBL] [Abstract][Full Text] [Related]
12. Chalcone derivatives inhibit glutathione S-transferase P1-1 activity: insights into the interaction mode of alpha, beta-unsaturated carbonyl compounds.
Wang J; Wang S; Song D; Zhao D; Sha Y; Jiang Y; Jing Y; Cheng M
Chem Biol Drug Des; 2009 May; 73(5):511-4. PubMed ID: 19323653
[TBL] [Abstract][Full Text] [Related]
13. 4-Aryl-1,3,2-oxathiazolylium-5-olate: a novel GST inhibitor to release JNK and activate c-Jun for cancer therapy.
Cui H; Shen J; Lu D; Zhang T; Zhang W; Sun D; Wang PG
Cancer Chemother Pharmacol; 2008 Aug; 62(3):509-15. PubMed ID: 18008069
[TBL] [Abstract][Full Text] [Related]
14. Rational design of platinum(IV) compounds to overcome glutathione-S-transferase mediated drug resistance.
Ang WH; Khalaila I; Allardyce CS; Juillerat-Jeanneret L; Dyson PJ
J Am Chem Soc; 2005 Feb; 127(5):1382-3. PubMed ID: 15686364
[TBL] [Abstract][Full Text] [Related]
15. Ethacrynic acid oxadiazole analogs induce apoptosis in malignant hematologic cells through downregulation of Mcl-1 and c-FLIP, which was attenuated by GSTP1-1.
Liu G; Wang R; Wang Y; Li P; Zhao G; Zhao L; Jing Y
Mol Cancer Ther; 2013 Sep; 12(9):1837-47. PubMed ID: 23804706
[TBL] [Abstract][Full Text] [Related]
16. Solution-phase parallel synthesis and screening of anti-tumor activities from fenbufen and ethacrynic acid libraries.
Su YH; Chiang LW; Jeng KC; Huang HL; Chen JT; Lin WJ; Huang CW; Yu CS
Bioorg Med Chem Lett; 2011 Mar; 21(5):1320-4. PubMed ID: 21315586
[TBL] [Abstract][Full Text] [Related]
17. Identification of potent type I MetAP inhibitors by simple bioisosteric replacement. Part 1: Synthesis and preliminary SAR studies of thiazole-4-carboxylic acid thiazol-2-ylamide derivatives.
Cui YM; Huang QQ; Xu J; Chen LL; Li JY; Ye QZ; Li J; Nan FJ
Bioorg Med Chem Lett; 2005 Aug; 15(16):3732-6. PubMed ID: 15993057
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and structure--activity relationship of new cytotoxic agents targeting human glutathione-S-transferases.
Rotili D; De Luca A; Tarantino D; Pezzola S; Forgione M; Morozzo Della Rocca B; Falconi M; Mai A; Caccuri AM
Eur J Med Chem; 2015 Jan; 89():156-71. PubMed ID: 25462236
[TBL] [Abstract][Full Text] [Related]
19. Pharmacologic or genetic manipulation of glutathione S-transferase P1-1 (GSTpi) influences cell proliferation pathways.
Ruscoe JE; Rosario LA; Wang T; Gaté L; Arifoglu P; Wolf CR; Henderson CJ; Ronai Z; Tew KD
J Pharmacol Exp Ther; 2001 Jul; 298(1):339-45. PubMed ID: 11408560
[TBL] [Abstract][Full Text] [Related]
20. The evaluation of novel natural products as inhibitors of human glutathione transferase P1-1.
Mukanganyama S; Bezabih M; Robert M; Ngadjui BT; Kapche GF; Ngandeu F; Abegaz B
J Enzyme Inhib Med Chem; 2011 Aug; 26(4):460-7. PubMed ID: 21028940
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
