BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

277 related articles for article (PubMed ID: 22378735)

  • 1. Maternal Mthfd1 disruption impairs fetal growth but does not cause neural tube defects in mice.
    Beaudin AE; Perry CA; Stabler SP; Allen RH; Stover PJ
    Am J Clin Nutr; 2012 Apr; 95(4):882-91. PubMed ID: 22378735
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Moderate folic acid supplementation and MTHFD1-synthetase deficiency in mice, a model for the R653Q variant, result in embryonic defects and abnormal placental development.
    Christensen KE; Hou W; Bahous RH; Deng L; Malysheva OV; Arning E; Bottiglieri T; Caudill MA; Jerome-Majewska LA; Rozen R
    Am J Clin Nutr; 2016 Nov; 104(5):1459-1469. PubMed ID: 27707701
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Low Dietary Folate Interacts with MTHFD1 Synthetase Deficiency in Mice, a Model for the R653Q Variant, to Increase Incidence of Developmental Delays and Defects.
    Christensen KE; Bahous RH; Hou W; Deng L; Malysheva OV; Arning E; Bottiglieri T; Caudill MA; Jerome-Majewska LA; Rozen R
    J Nutr; 2018 Apr; 148(4):501-509. PubMed ID: 29659962
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mild Choline Deficiency and MTHFD1 Synthetase Deficiency Interact to Increase Incidence of Developmental Delays and Defects in Mice.
    Christensen KE; Malysheva OV; Carlin S; Matias F; MacFarlane AJ; Jacobs RL; Caudill MA; Rozen R
    Nutrients; 2021 Dec; 14(1):. PubMed ID: 35011003
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A novel mouse model for genetic variation in 10-formyltetrahydrofolate synthetase exhibits disturbed purine synthesis with impacts on pregnancy and embryonic development.
    Christensen KE; Deng L; Leung KY; Arning E; Bottiglieri T; Malysheva OV; Caudill MA; Krupenko NI; Greene ND; Jerome-Majewska L; MacKenzie RE; Rozen R
    Hum Mol Genet; 2013 Sep; 22(18):3705-19. PubMed ID: 23704330
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Reduced MTHFD1 activity in male mice perturbs folate- and choline-dependent one-carbon metabolism as well as transsulfuration.
    Field MS; Shields KS; Abarinov EV; Malysheva OV; Allen RH; Stabler SP; Ash JA; Strupp BJ; Stover PJ; Caudill MA
    J Nutr; 2013 Jan; 143(1):41-5. PubMed ID: 23190757
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Deletion of the neural tube defect-associated gene
    Bryant JD; Sweeney SR; Sentandreu E; Shin M; Ipas H; Xhemalce B; Momb J; Tiziani S; Appling DR
    J Biol Chem; 2018 Apr; 293(16):5821-5833. PubMed ID: 29483189
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Deletion of Mthfd1l causes embryonic lethality and neural tube and craniofacial defects in mice.
    Momb J; Lewandowski JP; Bryant JD; Fitch R; Surman DR; Vokes SA; Appling DR
    Proc Natl Acad Sci U S A; 2013 Jan; 110(2):549-54. PubMed ID: 23267094
    [TBL] [Abstract][Full Text] [Related]  

  • 9. MTHFD1 formyltetrahydrofolate synthetase deficiency, a model for the MTHFD1 R653Q variant, leads to congenital heart defects in mice.
    Christensen KE; Deng L; Bahous RH; Jerome-Majewska LA; Rozen R
    Birth Defects Res A Clin Mol Teratol; 2015 Dec; 103(12):1031-8. PubMed ID: 26408344
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mthfd1 is a modifier of chemically induced intestinal carcinogenesis.
    MacFarlane AJ; Perry CA; McEntee MF; Lin DM; Stover PJ
    Carcinogenesis; 2011 Mar; 32(3):427-33. PubMed ID: 21156972
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mitochondrial one-carbon metabolism and neural tube defects.
    Momb J; Appling DR
    Birth Defects Res A Clin Mol Teratol; 2014 Aug; 100(8):576-83. PubMed ID: 24985542
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Deletion of one allele of Mthfd1 (methylenetetrahydrofolate dehydrogenase 1) impairs learning in mice.
    Pjetri E; Zeisel SH
    Behav Brain Res; 2017 Aug; 332():71-74. PubMed ID: 28559181
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Murine MTHFD1-synthetase deficiency, a model for the human MTHFD1 R653Q polymorphism, decreases growth of colorectal tumors.
    Lévesque N; Christensen KE; Van Der Kraak L; Best AF; Deng L; Caldwell D; MacFarlane AJ; Beauchemin N; Rozen R
    Mol Carcinog; 2017 Mar; 56(3):1030-1040. PubMed ID: 27597531
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Maternal dietary uridine causes, and deoxyuridine prevents, neural tube closure defects in a mouse model of folate-responsive neural tube defects.
    Martiniova L; Field MS; Finkelstein JL; Perry CA; Stover PJ
    Am J Clin Nutr; 2015 Apr; 101(4):860-9. PubMed ID: 25833982
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Shmt1 and de novo thymidylate biosynthesis underlie folate-responsive neural tube defects in mice.
    Beaudin AE; Abarinov EV; Noden DM; Perry CA; Chu S; Stabler SP; Allen RH; Stover PJ
    Am J Clin Nutr; 2011 Apr; 93(4):789-98. PubMed ID: 21346092
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Association of main folate metabolic pathway gene polymorphisms with neural tube defects in Han population of Northern China.
    Fang Y; Zhang R; Zhi X; Zhao L; Cao L; Wang Y; Cai C
    Childs Nerv Syst; 2018 Apr; 34(4):725-729. PubMed ID: 29392422
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dietary folate, but not choline, modifies neural tube defect risk in Shmt1 knockout mice.
    Beaudin AE; Abarinov EV; Malysheva O; Perry CA; Caudill M; Stover PJ
    Am J Clin Nutr; 2012 Jan; 95(1):109-14. PubMed ID: 22134951
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Gene-environment interactions in the causation of neural tube defects: folate deficiency increases susceptibility conferred by loss of Pax3 function.
    Burren KA; Savery D; Massa V; Kok RM; Scott JM; Blom HJ; Copp AJ; Greene ND
    Hum Mol Genet; 2008 Dec; 17(23):3675-85. PubMed ID: 18753144
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Genetic variants in phosphatidylethanolamine N-methyltransferase and methylenetetrahydrofolate dehydrogenase influence biomarkers of choline metabolism when folate intake is restricted.
    Ivanov A; Nash-Barboza S; Hinkis S; Caudill MA
    J Am Diet Assoc; 2009 Feb; 109(2):313-8. PubMed ID: 19167960
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Deletion of neural tube defect-associated gene Mthfd1l causes reduced cranial mesenchyme density.
    Shin M; Vaughn A; Momb J; Appling DR
    Birth Defects Res; 2019 Nov; 111(19):1520-1534. PubMed ID: 31518072
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.