281 related articles for article (PubMed ID: 22378735)
21. An NTD-associated polymorphism in the 3' UTR of MTHFD1L can affect disease risk by altering miRNA binding.
Minguzzi S; Selcuklu SD; Spillane C; Parle-McDermott A
Hum Mutat; 2014 Jan; 35(1):96-104. PubMed ID: 24123340
[TBL] [Abstract][Full Text] [Related]
22. Relationship of the MTHFD1 (rs2236225), eNOS (rs1799983), CBS (rs2850144) and ACE (rs4343) gene polymorphisms in a population of Iranian pediatric patients with congenital heart defects.
Khatami M; Ratki FM; Tajfar S; Akrami F
Kaohsiung J Med Sci; 2017 Sep; 33(9):442-448. PubMed ID: 28865601
[TBL] [Abstract][Full Text] [Related]
23. High levels of iron supplementation prevents neural tube defects in the Fpn1
Stokes BA; Sabatino JA; Zohn IE
Birth Defects Res; 2017 Jan; 109(2):81-91. PubMed ID: 28008752
[TBL] [Abstract][Full Text] [Related]
24. A polymorphism in the MTHFD1 gene increases a mother's risk of having an unexplained second trimester pregnancy loss.
Parle-McDermott A; Pangilinan F; Mills JL; Signore CC; Molloy AM; Cotter A; Conley M; Cox C; Kirke PN; Scott JM; Brody LC
Mol Hum Reprod; 2005 Jul; 11(7):477-80. PubMed ID: 16123074
[TBL] [Abstract][Full Text] [Related]
25. Maternal methylenetetrahydrofolate reductase deficiency and low dietary folate lead to adverse reproductive outcomes and congenital heart defects in mice.
Li D; Pickell L; Liu Y; Wu Q; Cohn JS; Rozen R
Am J Clin Nutr; 2005 Jul; 82(1):188-95. PubMed ID: 16002818
[TBL] [Abstract][Full Text] [Related]
26. Mitochondrial C1-tetrahydrofolate synthase (MTHFD1L) supports the flow of mitochondrial one-carbon units into the methyl cycle in embryos.
Pike ST; Rajendra R; Artzt K; Appling DR
J Biol Chem; 2010 Feb; 285(7):4612-20. PubMed ID: 19948730
[TBL] [Abstract][Full Text] [Related]
27. The MTHFD1 p.Arg653Gln variant alters enzyme function and increases risk for congenital heart defects.
Christensen KE; Rohlicek CV; Andelfinger GU; Michaud J; Bigras JL; Richter A; Mackenzie RE; Rozen R
Hum Mutat; 2009 Feb; 30(2):212-20. PubMed ID: 18767138
[TBL] [Abstract][Full Text] [Related]
28. Formate Supplementation May Prevent Some Neural Tube Defects that Prove Resistant to Folic Acid: Supplementation with formate rescued normal neural tube closure in more than three quarters of the embryos of novel folic acid-resistant neural tube defect mouse models.
Am J Med Genet A; 2018 Aug; 176(8):1697-1698. PubMed ID: 30136438
[No Abstract] [Full Text] [Related]
29. Association of neural tube defects with maternal alterations and genetic polymorphisms in one-carbon metabolic pathway.
Cai CQ; Fang YL; Shu JB; Zhao LS; Zhang RP; Cao LR; Wang YZ; Zhi XF; Cui HL; Shi OY; Liu W
Ital J Pediatr; 2019 Mar; 45(1):37. PubMed ID: 30867013
[TBL] [Abstract][Full Text] [Related]
30. Susceptibility to intestinal tumorigenesis in folate-deficient mice may be influenced by variation in one-carbon metabolism and DNA repair.
Knock E; Deng L; Krupenko N; Mohan RD; Wu Q; Leclerc D; Gupta S; Elmore CL; Kruger W; Tini M; Rozen R
J Nutr Biochem; 2011 Nov; 22(11):1022-9. PubMed ID: 21193302
[TBL] [Abstract][Full Text] [Related]
31. Dietary and genetic manipulations of folate metabolism differentially affect neocortical functions in mice.
Ash JA; Jiang X; Malysheva OV; Fiorenza CG; Bisogni AJ; Levitsky DA; Strawderman MS; Caudill MA; Stover PJ; Strupp BJ
Neurotoxicol Teratol; 2013; 38():79-91. PubMed ID: 23684804
[TBL] [Abstract][Full Text] [Related]
32. Arsenic trioxide targets MTHFD1 and SUMO-dependent nuclear de novo thymidylate biosynthesis.
Kamynina E; Lachenauer ER; DiRisio AC; Liebenthal RP; Field MS; Stover PJ
Proc Natl Acad Sci U S A; 2017 Mar; 114(12):E2319-E2326. PubMed ID: 28265077
[TBL] [Abstract][Full Text] [Related]
33. Deficient synthesis of MTHFD, a trifunctional folate-dependent enzyme, in the CHO Ade E mutant.
Mascisch A; Rozen R
Somat Cell Mol Genet; 1991 Jul; 17(4):391-8. PubMed ID: 1887335
[TBL] [Abstract][Full Text] [Related]
34. A polymorphism, R653Q, in the trifunctional enzyme methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase/formyltetrahydrofolate synthetase is a maternal genetic risk factor for neural tube defects: report of the Birth Defects Research Group.
Brody LC; Conley M; Cox C; Kirke PN; McKeever MP; Mills JL; Molloy AM; O'Leary VB; Parle-McDermott A; Scott JM; Swanson DA
Am J Hum Genet; 2002 Nov; 71(5):1207-15. PubMed ID: 12384833
[TBL] [Abstract][Full Text] [Related]
35. Nuclear enrichment of folate cofactors and methylenetetrahydrofolate dehydrogenase 1 (MTHFD1) protect de novo thymidylate biosynthesis during folate deficiency.
Field MS; Kamynina E; Agunloye OC; Liebenthal RP; Lamarre SG; Brosnan ME; Brosnan JT; Stover PJ
J Biol Chem; 2014 Oct; 289(43):29642-50. PubMed ID: 25213861
[TBL] [Abstract][Full Text] [Related]
36. Impact of methylenetetrahydrofolate reductase deficiency and low dietary folate on the development of neural tube defects in splotch mice.
Li D; Pickell L; Liu Y; Rozen R
Birth Defects Res A Clin Mol Teratol; 2006 Jan; 76(1):55-9. PubMed ID: 16397891
[TBL] [Abstract][Full Text] [Related]
37. Investigation of the effects of folate deficiency on embryonic development through the establishment of a folate deficient mouse model.
Burgoon JM; Selhub J; Nadeau M; Sadler TW
Teratology; 2002 May; 65(5):219-27. PubMed ID: 11967921
[TBL] [Abstract][Full Text] [Related]
38. Mitochondrial MTHFD2L is a dual redox cofactor-specific methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase expressed in both adult and embryonic tissues.
Shin M; Bryant JD; Momb J; Appling DR
J Biol Chem; 2014 May; 289(22):15507-17. PubMed ID: 24733394
[TBL] [Abstract][Full Text] [Related]
39. Folate status, homocysteine metabolism, and methylene tetrahydrofolate reductase genotype in rural South African blacks with a history of pregnancy complicated by neural tube defects.
Ubbink JB; Christianson A; Bester MJ; Van Allen MI; Venter PA; Delport R; Blom HJ; van der Merwe A; Potgieter H; Vermaak WJ
Metabolism; 1999 Feb; 48(2):269-74. PubMed ID: 10024094
[TBL] [Abstract][Full Text] [Related]
40. Strain-dependent dysregulation of one-carbon metabolism in male mice is associated with choline- and folate-deficient diet-induced liver injury.
Pogribny IP; Kutanzi K; Melnyk S; de Conti A; Tryndyak V; Montgomery B; Pogribna M; Muskhelishvili L; Latendresse JR; James SJ; Beland FA; Rusyn I
FASEB J; 2013 Jun; 27(6):2233-43. PubMed ID: 23439872
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
