202 related articles for article (PubMed ID: 22379189)
1. HDM2 promotes WIP1-mediated medulloblastoma growth.
Buss MC; Read TA; Schniederjan MJ; Gandhi K; Castellino RC
Neuro Oncol; 2012 Apr; 14(4):440-58. PubMed ID: 22379189
[TBL] [Abstract][Full Text] [Related]
2. The WIP1 oncogene promotes progression and invasion of aggressive medulloblastoma variants.
Buss MC; Remke M; Lee J; Gandhi K; Schniederjan MJ; Kool M; Northcott PA; Pfister SM; Taylor MD; Castellino RC
Oncogene; 2015 Feb; 34(9):1126-40. PubMed ID: 24632620
[TBL] [Abstract][Full Text] [Related]
3. WIP1 enhances tumor formation in a sonic hedgehog-dependent model of medulloblastoma.
Doucette TA; Yang Y; Pedone C; Kim JY; Dubuc A; Northcott PD; Taylor MD; Fults DW; Rao G
Neurosurgery; 2012 Apr; 70(4):1003-10; discussion 1010. PubMed ID: 22037313
[TBL] [Abstract][Full Text] [Related]
4. Medulloblastomas overexpress the p53-inactivating oncogene WIP1/PPM1D.
Castellino RC; De Bortoli M; Lu X; Moon SH; Nguyen TA; Shepard MA; Rao PH; Donehower LA; Kim JY
J Neurooncol; 2008 Feb; 86(3):245-56. PubMed ID: 17932621
[TBL] [Abstract][Full Text] [Related]
5. Pharmacological activation of the p53 pathway by nutlin-3 exerts anti-tumoral effects in medulloblastomas.
Künkele A; De Preter K; Heukamp L; Thor T; Pajtler KW; Hartmann W; Mittelbronn M; Grotzer MA; Deubzer HE; Speleman F; Schramm A; Eggert A; Schulte JH
Neuro Oncol; 2012 Jul; 14(7):859-69. PubMed ID: 22591662
[TBL] [Abstract][Full Text] [Related]
6. Abrogation of Wip1 expression by RITA-activated p53 potentiates apoptosis induction via activation of ATM and inhibition of HdmX.
Spinnler C; Hedström E; Li H; de Lange J; Nikulenkov F; Teunisse AF; Verlaan-de Vries M; Grinkevich V; Jochemsen AG; Selivanova G
Cell Death Differ; 2011 Nov; 18(11):1736-45. PubMed ID: 21546907
[TBL] [Abstract][Full Text] [Related]
7. WIP1 modulates responsiveness to Sonic Hedgehog signaling in neuronal precursor cells and medulloblastoma.
Wen J; Lee J; Malhotra A; Nahta R; Arnold AR; Buss MC; Brown BD; Maier C; Kenney AM; Remke M; Ramaswamy V; Taylor MD; Castellino RC
Oncogene; 2016 Oct; 35(42):5552-5564. PubMed ID: 27086929
[TBL] [Abstract][Full Text] [Related]
8. Cooperation of Nutlin-3a and a Wip1 inhibitor to induce p53 activity.
Sriraman A; Radovanovic M; Wienken M; Najafova Z; Li Y; Dobbelstein M
Oncotarget; 2016 May; 7(22):31623-38. PubMed ID: 27183917
[TBL] [Abstract][Full Text] [Related]
9. p53 Regulates LIF expression in human medulloblastoma cells.
Baxter EW; Milner J
J Neurooncol; 2010 May; 97(3):373-82. PubMed ID: 19907922
[TBL] [Abstract][Full Text] [Related]
10. WIP1 phosphatase as a potential therapeutic target in neuroblastoma.
Richter M; Dayaram T; Gilmartin AG; Ganji G; Pemmasani SK; Van Der Key H; Shohet JM; Donehower LA; Kumar R
PLoS One; 2015; 10(2):e0115635. PubMed ID: 25658463
[TBL] [Abstract][Full Text] [Related]
11. p53 Function Is Compromised by Inhibitor 2 of Phosphatase 2A in Sonic Hedgehog Medulloblastoma.
Wei Y; Maximov V; Morrissy SA; Taylor MD; Pallas DC; Kenney AM
Mol Cancer Res; 2019 Jan; 17(1):186-198. PubMed ID: 30224541
[TBL] [Abstract][Full Text] [Related]
12. Targeting negative regulation of p53 by MDM2 and WIP1 as a therapeutic strategy in cutaneous melanoma.
Wu CE; Esfandiari A; Ho YH; Wang N; Mahdi AK; Aptullahoglu E; Lovat P; Lunec J
Br J Cancer; 2018 Feb; 118(4):495-508. PubMed ID: 29235570
[TBL] [Abstract][Full Text] [Related]
13. The Wip1 phosphatase and Mdm2: cracking the "Wip" on p53 stability.
Lu X; Nguyen TA; Zhang X; Donehower LA
Cell Cycle; 2008 Jan; 7(2):164-8. PubMed ID: 18333294
[TBL] [Abstract][Full Text] [Related]
14. DNA damage-induced regulatory interplay between DAXX, p53, ATM kinase and Wip1 phosphatase.
Brazina J; Svadlenka J; Macurek L; Andera L; Hodny Z; Bartek J; Hanzlikova H
Cell Cycle; 2015; 14(3):375-87. PubMed ID: 25659035
[TBL] [Abstract][Full Text] [Related]
15. Inhibition of WIP1 phosphatase sensitizes breast cancer cells to genotoxic stress and to MDM2 antagonist nutlin-3.
Pechackova S; Burdova K; Benada J; Kleiblova P; Jenikova G; Macurek L
Oncotarget; 2016 Mar; 7(12):14458-75. PubMed ID: 26883108
[TBL] [Abstract][Full Text] [Related]
16. The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop.
Lu X; Ma O; Nguyen TA; Jones SN; Oren M; Donehower LA
Cancer Cell; 2007 Oct; 12(4):342-54. PubMed ID: 17936559
[TBL] [Abstract][Full Text] [Related]
17. BAI1 Suppresses Medulloblastoma Formation by Protecting p53 from Mdm2-Mediated Degradation.
Zhu D; Osuka S; Zhang Z; Reichert ZR; Yang L; Kanemura Y; Jiang Y; You S; Zhang H; Devi NS; Bhattacharya D; Takano S; Gillespie GY; Macdonald T; Tan C; Nishikawa R; Nelson WG; Olson JJ; Van Meir EG
Cancer Cell; 2018 Jun; 33(6):1004-1016.e5. PubMed ID: 29894688
[TBL] [Abstract][Full Text] [Related]
18. Overexpression of the wip1 gene abrogates the p38 MAPK/p53/Wip1 pathway and silences p16 expression in human breast cancers.
Yu E; Ahn YS; Jang SJ; Kim MJ; Yoon HS; Gong G; Choi J
Breast Cancer Res Treat; 2007 Mar; 101(3):269-78. PubMed ID: 16897432
[TBL] [Abstract][Full Text] [Related]
19. RITA displays anti-tumor activity in medulloblastomas independent of TP53 status.
Gottlieb A; Althoff K; Grunewald L; Thor T; Odersky A; Schulte M; Deubzer HE; Heukamp L; Eggert A; Schramm A; Schulte JH; Künkele A
Oncotarget; 2017 Apr; 8(17):27882-27891. PubMed ID: 28427187
[TBL] [Abstract][Full Text] [Related]
20. Alterations in gene expression and sensitivity to genotoxic stress following HdmX or Hdm2 knockdown in human tumor cells harboring wild-type p53.
Heminger K; Markey M; Mpagi M; Berberich SJ
Aging (Albany NY); 2009 Jan; 1(1):89-108. PubMed ID: 19946469
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]