BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

189 related articles for article (PubMed ID: 22382519)

  • 1. Lactogens protect rodent and human beta cells against glucolipotoxicity-induced cell death through Janus kinase-2 (JAK2)/signal transducer and activator of transcription-5 (STAT5) signalling.
    Kondegowda NG; Mozar A; Chin C; Otero A; Garcia-Ocaña A; Vasavada RC
    Diabetologia; 2012 Jun; 55(6):1721-32. PubMed ID: 22382519
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Lactogens promote beta cell survival through JAK2/STAT5 activation and Bcl-XL upregulation.
    Fujinaka Y; Takane K; Yamashita H; Vasavada RC
    J Biol Chem; 2007 Oct; 282(42):30707-17. PubMed ID: 17728251
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Lactogens Reduce Endoplasmic Reticulum Stress-Induced Rodent and Human β-Cell Death and Diabetes Incidence in Akita Mice.
    Li R; Kondegowda NG; Filipowska J; Hampton RF; Leblanc S; Garcia-Ocana A; Vasavada RC
    Diabetes; 2020 Jul; 69(7):1463-1475. PubMed ID: 32332156
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Stimulation of pancreatic beta-cell proliferation by growth hormone is glucose-dependent: signal transduction via janus kinase 2 (JAK2)/signal transducer and activator of transcription 5 (STAT5) with no crosstalk to insulin receptor substrate-mediated mitogenic signalling.
    Cousin SP; Hügl SR; Myers MG; White MF; Reifel-Miller A; Rhodes CJ
    Biochem J; 1999 Dec; 344 Pt 3(Pt 3):649-58. PubMed ID: 10585851
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Growth hormone- and prolactin-induced proliferation of insulinoma cells, INS-1, depends on activation of STAT5 (signal transducer and activator of transcription 5).
    Friedrichsen BN; Galsgaard ED; Nielsen JH; Møldrup A
    Mol Endocrinol; 2001 Jan; 15(1):136-48. PubMed ID: 11145745
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Augmented Stat5 Signaling Bypasses Multiple Impediments to Lactogen-Mediated Proliferation in Human β-Cells.
    Chen H; Kleinberger JW; Takane KK; Salim F; Fiaschi-Taesch N; Pappas K; Parsons R; Jiang J; Zhang Y; Liu H; Wang P; Bender AS; Frank SJ; Stewart AF
    Diabetes; 2015 Nov; 64(11):3784-97. PubMed ID: 26159175
    [TBL] [Abstract][Full Text] [Related]  

  • 7. STAT5 activation by human GH protects insulin-producing cells against interleukin-1beta, interferon-gamma and tumour necrosis factor-alpha-induced apoptosis independent of nitric oxide production.
    Jensen J; Galsgaard ED; Karlsen AE; Lee YC; Nielsen JH
    J Endocrinol; 2005 Oct; 187(1):25-36. PubMed ID: 16214938
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Constitutive activation of JAK2 in mammary epithelium elevates Stat5 signalling, promotes alveologenesis and resistance to cell death, and contributes to tumourigenesis.
    Caffarel MM; Zaragoza R; Pensa S; Li J; Green AR; Watson CJ
    Cell Death Differ; 2012 Mar; 19(3):511-22. PubMed ID: 21941370
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Expression mechanism of tryptophan hydroxylase 1 in mouse islets during pregnancy.
    Iida H; Ogihara T; Min MK; Hara A; Kim YG; Fujimaki K; Tamaki M; Fujitani Y; Kim H; Watada H
    J Mol Endocrinol; 2015 Aug; 55(1):41-53. PubMed ID: 26136513
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Suppressor of cytokine signalling-6 promotes neurite outgrowth via JAK2/STAT5-mediated signalling pathway, involving negative feedback inhibition.
    Gupta S; Mishra K; Surolia A; Banerjee K
    PLoS One; 2011; 6(11):e26674. PubMed ID: 22125600
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Monocyte chemoattractant protein-1 expression is enhanced by granulocyte-macrophage colony-stimulating factor via Jak2-Stat5 signaling and inhibited by atorvastatin in human monocytic U937 cells.
    Tanimoto A; Murata Y; Wang KY; Tsutsui M; Kohno K; Sasaguri Y
    J Biol Chem; 2008 Feb; 283(8):4643-51. PubMed ID: 18089573
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effect of homologous placental lactogens, prolactins, and growth hormones on islet B-cell division and insulin secretion in rat, mouse, and human islets: implication for placental lactogen regulation of islet function during pregnancy.
    Brelje TC; Scharp DW; Lacy PE; Ogren L; Talamantes F; Robertson M; Friesen HG; Sorenson RL
    Endocrinology; 1993 Feb; 132(2):879-87. PubMed ID: 8425500
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Placental lactogens induce serotonin biosynthesis in a subset of mouse beta cells during pregnancy.
    Schraenen A; Lemaire K; de Faudeur G; Hendrickx N; Granvik M; Van Lommel L; Mallet J; Vodjdani G; Gilon P; Binart N; in't Veld P; Schuit F
    Diabetologia; 2010 Dec; 53(12):2589-99. PubMed ID: 20938637
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Three Tyrosine Residues in the Erythropoietin Receptor Are Essential for Janus Kinase 2 V617F Mutant-induced Tumorigenesis.
    Ueda F; Tago K; Tamura H; Funakoshi-Tago M
    J Biol Chem; 2017 Feb; 292(5):1826-1846. PubMed ID: 27998978
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Jak2/Stat5 signaling in mammogenesis, breast cancer initiation and progression.
    Wagner KU; Rui H
    J Mammary Gland Biol Neoplasia; 2008 Mar; 13(1):93-103. PubMed ID: 18228120
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel mechanism for Fc{epsilon}RI-mediated signal transducer and activator of transcription 5 (STAT5) tyrosine phosphorylation and the selective influence of STAT5B over mast cell cytokine production.
    Pullen NA; Barnstein BO; Falanga YT; Wang Z; Suzuki R; Tamang TD; Khurana MC; Harry EA; Draber P; Bunting KD; Mizuno K; Wilson BS; Ryan JJ
    J Biol Chem; 2012 Jan; 287(3):2045-54. PubMed ID: 22130676
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Essential role for Stat5 in the neurotrophic but not in the neuroprotective effect of erythropoietin.
    Byts N; Samoylenko A; Fasshauer T; Ivanisevic M; Hennighausen L; Ehrenreich H; Sirén AL
    Cell Death Differ; 2008 Apr; 15(4):783-92. PubMed ID: 18259195
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Autocrine prolactin promotes prostate cancer cell growth via Janus kinase-2-signal transducer and activator of transcription-5a/b signaling pathway.
    Dagvadorj A; Collins S; Jomain JB; Abdulghani J; Karras J; Zellweger T; Li H; Nurmi M; Alanen K; Mirtti T; Visakorpi T; Bubendorf L; Goffin V; Nevalainen MT
    Endocrinology; 2007 Jul; 148(7):3089-101. PubMed ID: 17412813
    [TBL] [Abstract][Full Text] [Related]  

  • 19. LPS-induced SOCS3 antagonizes the JAK2-STAT5 pathway and inhibits β-casein synthesis in bovine mammary epithelial cells.
    Geng Z; Shan X; Lian S; Wang J; Wu R
    Life Sci; 2021 Aug; 278():119547. PubMed ID: 33930363
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Protective role of the ELOVL2/docosahexaenoic acid axis in glucolipotoxicity-induced apoptosis in rodent beta cells and human islets.
    Bellini L; Campana M; Rouch C; Chacinska M; Bugliani M; Meneyrol K; Hainault I; Lenoir V; Denom J; Véret J; Kassis N; Thorens B; Ibberson M; Marchetti P; Blachnio-Zabielska A; Cruciani-Guglielmacci C; Prip-Buus C; Magnan C; Le Stunff H
    Diabetologia; 2018 Aug; 61(8):1780-1793. PubMed ID: 29754287
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.