BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

148 related articles for article (PubMed ID: 22382662)

  • 1. Molecular approaches to the treatment, prophylaxis, and diagnosis of Alzheimer's disease: possible involvement of HRD1, a novel molecule related to endoplasmic reticulum stress, in Alzheimer's disease.
    Kaneko M; Okuma Y; Nomura Y
    J Pharmacol Sci; 2012; 118(3):325-30. PubMed ID: 22382662
    [TBL] [Abstract][Full Text] [Related]  

  • 2. [Physiological Roles of Ubiquitin Ligases Related to the Endoplasmic Reticulum].
    Kaneko M
    Yakugaku Zasshi; 2016; 136(6):805-9. PubMed ID: 27252059
    [TBL] [Abstract][Full Text] [Related]  

  • 3. [Molecular pharmacological studies on the protection mechanism against endoplasmic reticulum stress-induced neurodegenerative disease].
    Kaneko M
    Yakugaku Zasshi; 2012; 132(12):1437-42. PubMed ID: 23208051
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Loss of HRD1-mediated protein degradation causes amyloid precursor protein accumulation and amyloid-beta generation.
    Kaneko M; Koike H; Saito R; Kitamura Y; Okuma Y; Nomura Y
    J Neurosci; 2010 Mar; 30(11):3924-32. PubMed ID: 20237263
    [TBL] [Abstract][Full Text] [Related]  

  • 5. [Pharmacological studies on neurodegenerative diseases focusing on refolding and degradation of unfolded proteins in the endoplasmic reticulum].
    Nomura Y
    Yakugaku Zasshi; 2014; 134(4):537-43. PubMed ID: 24694815
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Possible involvement of ubiquitin ligase HRD1 insolubilization in amyloid β generation.
    Kaneko M; Saito R; Okuma Y; Nomura Y
    Biol Pharm Bull; 2012; 35(2):269-72. PubMed ID: 22293361
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Correlation between decrease in protein levels of ubiquitin ligase HRD1 and amyloid-beta production.
    Saito R; Kaneko M; Okuma Y; Nomura Y
    J Pharmacol Sci; 2010; 113(3):285-8. PubMed ID: 20606367
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effects of oxidative stress on the solubility of HRD1, a ubiquitin ligase implicated in Alzheimer's disease.
    Saito R; Kaneko M; Kitamura Y; Takata K; Kawada K; Okuma Y; Nomura Y
    PLoS One; 2014; 9(5):e94576. PubMed ID: 24788773
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Endoplasmic reticulum-associated degradation and beyond: The multitasking roles for HRD1 in immune regulation and autoimmunity.
    Xu Y; Fang D
    J Autoimmun; 2020 May; 109():102423. PubMed ID: 32057541
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Acute ER stress regulates amyloid precursor protein processing through ubiquitin-dependent degradation.
    Jung ES; Hong H; Kim C; Mook-Jung I
    Sci Rep; 2015 Mar; 5():8805. PubMed ID: 25740315
    [TBL] [Abstract][Full Text] [Related]  

  • 11. USP19-Mediated Deubiquitination Facilitates the Stabilization of HRD1 Ubiquitin Ligase.
    Harada K; Kato M; Nakamura N
    Int J Mol Sci; 2016 Nov; 17(11):. PubMed ID: 27827840
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Geniposide Increases Unfolded Protein Response-Mediating HRD1 Expression to Accelerate APP Degradation in Primary Cortical Neurons.
    Cui H; Deng M; Zhang Y; Yin F; Liu J
    Neurochem Res; 2018 Mar; 43(3):669-680. PubMed ID: 29427280
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Association of the SEL1L protein transmembrane domain with HRD1 ubiquitin ligase regulates ERAD-L.
    Hosokawa N; Wada I
    FEBS J; 2016 Jan; 283(1):157-72. PubMed ID: 26471130
    [TBL] [Abstract][Full Text] [Related]  

  • 14. UFMylation of HRD1 regulates endoplasmic reticulum homeostasis.
    Luo H; Jiao QB; Shen CB; Gong WY; Yuan JH; Liu YY; Chen Z; Liu J; Xu XL; Cong YS; Zhang XW
    FASEB J; 2023 Nov; 37(11):e23221. PubMed ID: 37795761
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hrd1 and ER-Associated Protein Degradation, ERAD, are Critical Elements of the Adaptive ER Stress Response in Cardiac Myocytes.
    Doroudgar S; Völkers M; Thuerauf DJ; Khan M; Mohsin S; Respress JL; Wang W; Gude N; Müller OJ; Wehrens XH; Sussman MA; Glembotski CC
    Circ Res; 2015 Aug; 117(6):536-46. PubMed ID: 26137860
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hrd1 facilitates tau degradation and promotes neuron survival.
    Shen YX; Sun AM; Fang S; Feng LJ; Li Q; Hou HL; Liu C; Wang HP; Shen JL; Luo J; Zhou JN
    Curr Mol Med; 2012 Feb; 12(2):138-52. PubMed ID: 22280354
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ubiquitin ligase HMG-CoA reductase degradation 1 (HRD1) prevents cell death in a cellular model of Parkinson's disease.
    Omura T; Matsuda H; Nomura L; Imai S; Denda M; Nakagawa S; Yonezawa A; Nakagawa T; Yano I; Matsubara K
    Biochem Biophys Res Commun; 2018 Nov; 506(3):516-521. PubMed ID: 30361093
    [TBL] [Abstract][Full Text] [Related]  

  • 18. HRD1 in human malignant neoplasms: Molecular mechanisms and novel therapeutic strategy for cancer.
    Karamali N; Ebrahimnezhad S; Khaleghi Moghadam R; Daneshfar N; Rezaiemanesh A
    Life Sci; 2022 Jul; 301():120620. PubMed ID: 35533759
    [TBL] [Abstract][Full Text] [Related]  

  • 19. gp78 functions downstream of Hrd1 to promote degradation of misfolded proteins of the endoplasmic reticulum.
    Zhang T; Xu Y; Liu Y; Ye Y
    Mol Biol Cell; 2015 Dec; 26(24):4438-50. PubMed ID: 26424800
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cholesterol-induced HRD1 reduction accelerates vascular smooth muscle cell senescence via stimulation of endoplasmic reticulum stress-induced reactive oxygen species.
    Wang L; Wang M; Niu H; Zhi Y; Li S; He X; Ren Z; Wen S; Wu L; Wen S; Zhang R; Wen Z; Yang J; Zhang X; Chen Y; Qian X; Shi G
    J Mol Cell Cardiol; 2024 Feb; 187():51-64. PubMed ID: 38171043
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.