323 related articles for article (PubMed ID: 22383797)
1. Btk levels set the threshold for B-cell activation and negative selection of autoreactive B cells in mice.
Kil LP; de Bruijn MJ; van Nimwegen M; Corneth OB; van Hamburg JP; Dingjan GM; Thaiss F; Rimmelzwaan GF; Elewaut D; Delsing D; van Loo PF; Hendriks RW
Blood; 2012 Apr; 119(16):3744-56. PubMed ID: 22383797
[TBL] [Abstract][Full Text] [Related]
2. The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy.
Honigberg LA; Smith AM; Sirisawad M; Verner E; Loury D; Chang B; Li S; Pan Z; Thamm DH; Miller RA; Buggy JJ
Proc Natl Acad Sci U S A; 2010 Jul; 107(29):13075-80. PubMed ID: 20615965
[TBL] [Abstract][Full Text] [Related]
3. Modulating proximal cell signaling by targeting Btk ameliorates humoral autoimmunity and end-organ disease in murine lupus.
Hutcheson J; Vanarsa K; Bashmakov A; Grewal S; Sajitharan D; Chang BY; Buggy JJ; Zhou XJ; Du Y; Satterthwaite AB; Mohan C
Arthritis Res Ther; 2012 Nov; 14(6):R243. PubMed ID: 23136880
[TBL] [Abstract][Full Text] [Related]
4. Toll-Like Receptor Signaling Drives Btk-Mediated Autoimmune Disease.
Rip J; de Bruijn MJW; Appelman MK; Pal Singh S; Hendriks RW; Corneth OBJ
Front Immunol; 2019; 10():95. PubMed ID: 30761150
[TBL] [Abstract][Full Text] [Related]
5. Selective inhibition of BTK prevents murine lupus and antibody-mediated glomerulonephritis.
Rankin AL; Seth N; Keegan S; Andreyeva T; Cook TA; Edmonds J; Mathialagan N; Benson MJ; Syed J; Zhan Y; Benoit SE; Miyashiro JS; Wood N; Mohan S; Peeva E; Ramaiah SK; Messing D; Homer BL; Dunussi-Joannopoulos K; Nickerson-Nutter CL; Schnute ME; Douhan J
J Immunol; 2013 Nov; 191(9):4540-50. PubMed ID: 24068666
[TBL] [Abstract][Full Text] [Related]
6. Btk regulates localization, in vivo activation, and class switching of anti-DNA B cells.
Halcomb KE; Musuka S; Gutierrez T; Wright HL; Satterthwaite AB
Mol Immunol; 2008 Dec; 46(2):233-41. PubMed ID: 18849077
[TBL] [Abstract][Full Text] [Related]
7. Function of Bruton's tyrosine kinase during B cell development is partially independent of its catalytic activity.
Middendorp S; Dingjan GM; Maas A; Dahlenborg K; Hendriks RW
J Immunol; 2003 Dec; 171(11):5988-96. PubMed ID: 14634110
[TBL] [Abstract][Full Text] [Related]
8. Enhanced Expression of Bruton's Tyrosine Kinase in B Cells Drives Systemic Autoimmunity by Disrupting T Cell Homeostasis.
Corneth OB; de Bruijn MJ; Rip J; Asmawidjaja PS; Kil LP; Hendriks RW
J Immunol; 2016 Jul; 197(1):58-67. PubMed ID: 27226091
[TBL] [Abstract][Full Text] [Related]
9. BTK Signaling in B Cell Differentiation and Autoimmunity.
Corneth OBJ; Klein Wolterink RGJ; Hendriks RW
Curr Top Microbiol Immunol; 2016; 393():67-105. PubMed ID: 26341110
[TBL] [Abstract][Full Text] [Related]
10. Dual phosphorylation of Btk by Akt/protein kinase b provides docking for 14-3-3ζ, regulates shuttling, and attenuates both tonic and induced signaling in B cells.
Mohammad DK; Nore BF; Hussain A; Gustafsson MO; Mohamed AJ; Smith CI
Mol Cell Biol; 2013 Aug; 33(16):3214-26. PubMed ID: 23754751
[TBL] [Abstract][Full Text] [Related]
11. Efficacy and Pharmacodynamic Modeling of the BTK Inhibitor Evobrutinib in Autoimmune Disease Models.
Haselmayer P; Camps M; Liu-Bujalski L; Nguyen N; Morandi F; Head J; O'Mahony A; Zimmerli SC; Bruns L; Bender AT; Schroeder P; Grenningloh R
J Immunol; 2019 May; 202(10):2888-2906. PubMed ID: 30988116
[TBL] [Abstract][Full Text] [Related]
12. Constitutive activation of Bruton's tyrosine kinase induces the formation of autoreactive IgM plasma cells.
Kersseboom R; Kil L; Flierman R; van der Zee M; Dingjan GM; Middendorp S; Maas A; Hendriks RW
Eur J Immunol; 2010 Sep; 40(9):2643-54. PubMed ID: 20623551
[TBL] [Abstract][Full Text] [Related]
13. IL-21 promotes the production of anti-DNA IgG but is dispensable for kidney damage in lyn-/- mice.
Gutierrez T; Mayeux JM; Ortega SB; Karandikar NJ; Li QZ; Rakheja D; Zhou XJ; Satterthwaite AB
Eur J Immunol; 2013 Feb; 43(2):382-93. PubMed ID: 23169140
[TBL] [Abstract][Full Text] [Related]
14. Reduced dosage of Bruton's tyrosine kinase uncouples B cell hyperresponsiveness from autoimmunity in lyn-/- mice.
Whyburn LR; Halcomb KE; Contreras CM; Lowell CA; Witte ON; Satterthwaite AB
J Immunol; 2003 Aug; 171(4):1850-8. PubMed ID: 12902486
[TBL] [Abstract][Full Text] [Related]
15. Sustained correction of B-cell development and function in a murine model of X-linked agammaglobulinemia (XLA) using retroviral-mediated gene transfer.
Yu PW; Tabuchi RS; Kato RM; Astrakhan A; Humblet-Baron S; Kipp K; Chae K; Ellmeier W; Witte ON; Rawlings DJ
Blood; 2004 Sep; 104(5):1281-90. PubMed ID: 15142874
[TBL] [Abstract][Full Text] [Related]
16. Bruton's tyrosine kinase and SLP-65 regulate pre-B cell differentiation and the induction of Ig light chain gene rearrangement.
Kersseboom R; Ta VB; Zijlstra AJ; Middendorp S; Jumaa H; van Loo PF; Hendriks RW
J Immunol; 2006 Apr; 176(8):4543-52. PubMed ID: 16585544
[TBL] [Abstract][Full Text] [Related]
17. LRRK2 is involved in the pathogenesis of system lupus erythematosus through promoting pathogenic antibody production.
Zhang M; Yao C; Cai J; Liu S; Liu XN; Chen Y; Wang S; Ji P; Pan M; Kang Z; Wang Y
J Transl Med; 2019 Jan; 17(1):37. PubMed ID: 30670047
[TBL] [Abstract][Full Text] [Related]
18. Suppression of glomerulonephritis in lupus-prone NZB × NZW mice by RN486, a selective inhibitor of Bruton's tyrosine kinase.
Mina-Osorio P; LaStant J; Keirstead N; Whittard T; Ayala J; Stefanova S; Garrido R; Dimaano N; Hilton H; Giron M; Lau KY; Hang J; Postelnek J; Kim Y; Min S; Patel A; Woods J; Ramanujam M; DeMartino J; Narula S; Xu D
Arthritis Rheum; 2013 Sep; 65(9):2380-91. PubMed ID: 23754328
[TBL] [Abstract][Full Text] [Related]
19. Posttranscriptional regulation of Bruton's tyrosine kinase expression in antigen receptor-stimulated splenic B cells.
Nisitani S; Satterthwaite AB; Akashi K; Weissman IL; Witte ON; Wahl MI
Proc Natl Acad Sci U S A; 2000 Mar; 97(6):2737-42. PubMed ID: 10688914
[TBL] [Abstract][Full Text] [Related]
20. Impaired B Cell Apoptosis Results in Autoimmunity That Is Alleviated by Ablation of Btk.
Wright JA; Bazile C; Clark ES; Carlesso G; Boucher J; Kleiman E; Mahmoud T; Cheng LI; López-Rodríguez DM; Satterthwaite AB; Altman NH; Greidinger EL; Khan WN
Front Immunol; 2021; 12():705307. PubMed ID: 34512628
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
