BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

554 related articles for article (PubMed ID: 22383888)

  • 21. Towards a transgenic model of Huntington's disease in a non-human primate.
    Yang SH; Cheng PH; Banta H; Piotrowska-Nitsche K; Yang JJ; Cheng EC; Snyder B; Larkin K; Liu J; Orkin J; Fang ZH; Smith Y; Bachevalier J; Zola SM; Li SH; Li XJ; Chan AW
    Nature; 2008 Jun; 453(7197):921-4. PubMed ID: 18488016
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Lack of huntingtin promotes neural stem cells differentiation into glial cells while neurons expressing huntingtin with expanded polyglutamine tracts undergo cell death.
    Conforti P; Camnasio S; Mutti C; Valenza M; Thompson M; Fossale E; Zeitlin S; MacDonald ME; Zuccato C; Cattaneo E
    Neurobiol Dis; 2013 Feb; 50():160-70. PubMed ID: 23089356
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Investigations of Huntington's Disease and Huntington's Disease-Like Syndromes in Indian Choreatic Patients.
    Kaur J; Parveen S; Shamim U; Sharma P; Suroliya V; Sonkar AK; Ahmad I; Garg J; Anand KS; Laskar S; Chowdhury D; Kushwaha S; Goyal V; Srivastava AK; Singh G; Faruq M
    J Huntingtons Dis; 2020; 9(3):283-289. PubMed ID: 32675418
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Wild type Huntingtin reduces the cellular toxicity of mutant Huntingtin in mammalian cell models of Huntington's disease.
    Ho LW; Brown R; Maxwell M; Wyttenbach A; Rubinsztein DC
    J Med Genet; 2001 Jul; 38(7):450-2. PubMed ID: 11432963
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Allele-selective inhibition of mutant huntingtin expression with antisense oligonucleotides targeting the expanded CAG repeat.
    Gagnon KT; Pendergraff HM; Deleavey GF; Swayze EE; Potier P; Randolph J; Roesch EB; Chattopadhyaya J; Damha MJ; Bennett CF; Montaillier C; Lemaitre M; Corey DR
    Biochemistry; 2010 Nov; 49(47):10166-78. PubMed ID: 21028906
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Huntington's disease: how intermediate are intermediate repeat lengths?
    Squitieri F; Jankovic J
    Mov Disord; 2012 Dec; 27(14):1714-7. PubMed ID: 23008174
    [TBL] [Abstract][Full Text] [Related]  

  • 27. HD CAGnome: a search tool for huntingtin CAG repeat length-correlated genes.
    Galkina EI; Shin A; Coser KR; Shioda T; Kohane IS; Seong IS; Wheeler VC; Gusella JF; Macdonald ME; Lee JM
    PLoS One; 2014; 9(4):e95556. PubMed ID: 24751919
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Multiple clinical features of Huntington's disease correlate with mutant HTT gene CAG repeat lengths and neurodegeneration.
    Podvin S; Reardon HT; Yin K; Mosier C; Hook V
    J Neurol; 2019 Mar; 266(3):551-564. PubMed ID: 29956026
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Examination of mesenchymal stem cell-mediated RNAi transfer to Huntington's disease affected neuronal cells for reduction of huntingtin.
    Olson SD; Kambal A; Pollock K; Mitchell GM; Stewart H; Kalomoiris S; Cary W; Nacey C; Pepper K; Nolta JA
    Mol Cell Neurosci; 2012 Mar; 49(3):271-81. PubMed ID: 22198539
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Increased caspase-2, calpain activations and decreased mitochondrial complex II activity in cells expressing exogenous huntingtin exon 1 containing CAG repeat in the pathogenic range.
    Majumder P; Raychaudhuri S; Chattopadhyay B; Bhattacharyya NP
    Cell Mol Neurobiol; 2007 Dec; 27(8):1127-45. PubMed ID: 17902043
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Does the Mutant CAG Expansion in Huntingtin mRNA Interfere with Exonucleolytic Cleavage of its First Exon?
    Liu W; Pfister EL; Kennington LA; Chase KO; Mueller C; DiFiglia M; Aronin N
    J Huntingtons Dis; 2016; 5(1):33-8. PubMed ID: 27003665
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Cellular Analysis of Silencing the Huntington's Disease Gene Using AAV9 Mediated Delivery of Artificial Micro RNA into the Striatum of Q140/Q140 Mice.
    Keeler AM; Sapp E; Chase K; Sottosanti E; Danielson E; Pfister E; Stoica L; DiFiglia M; Aronin N; Sena-Esteves M
    J Huntingtons Dis; 2016 Oct; 5(3):239-248. PubMed ID: 27689620
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Huntington's disease brain-derived small RNAs recapitulate associated neuropathology in mice.
    Creus-Muncunill J; Guisado-Corcoll A; Venturi V; Pantano L; Escaramís G; García de Herreros M; Solaguren-Beascoa M; Gámez-Valero A; Navarrete C; Masana M; Llorens F; Diaz-Lucena D; Pérez-Navarro E; Martí E
    Acta Neuropathol; 2021 Apr; 141(4):565-584. PubMed ID: 33547932
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Novel BAC Mouse Model of Huntington's Disease with 225 CAG Repeats Exhibits an Early Widespread and Stable Degenerative Phenotype.
    Wegrzynowicz M; Bichell TJ; Soares BD; Loth MK; McGlothan JS; Mori S; Alikhan FS; Hua K; Coughlin JM; Holt HK; Jetter CS; Pomper MG; Osmand AP; Guilarte TR; Bowman AB
    J Huntingtons Dis; 2015; 4(1):17-36. PubMed ID: 26333255
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Investigation of the Influence of TBP CAG/CAA Repeats in Conjunction with HTT CAG Repeats on Huntington's Disease Age at Onset in a Brazilian Sample.
    da Silva IDS; Apolinário TA; de Andrade Agostinho L; Paiva CLA
    J Mol Neurosci; 2022 May; 72(5):1116-1124. PubMed ID: 35275350
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Derivation of Huntington's disease-affected human embryonic stem cell lines.
    Bradley CK; Scott HA; Chami O; Peura TT; Dumevska B; Schmidt U; Stojanov T
    Stem Cells Dev; 2011 Mar; 20(3):495-502. PubMed ID: 20649476
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Msh2 acts in medium-spiny striatal neurons as an enhancer of CAG instability and mutant huntingtin phenotypes in Huntington's disease knock-in mice.
    Kovalenko M; Dragileva E; St Claire J; Gillis T; Guide JR; New J; Dong H; Kucherlapati R; Kucherlapati MH; Ehrlich ME; Lee JM; Wheeler VC
    PLoS One; 2012; 7(9):e44273. PubMed ID: 22970194
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Promotion of somatic CAG repeat expansion by Fan1 knock-out in Huntington's disease knock-in mice is blocked by Mlh1 knock-out.
    Loupe JM; Pinto RM; Kim KH; Gillis T; Mysore JS; Andrew MA; Kovalenko M; Murtha R; Seong I; Gusella JF; Kwak S; Howland D; Lee R; Lee JM; Wheeler VC; MacDonald ME
    Hum Mol Genet; 2020 Nov; 29(18):3044-3053. PubMed ID: 32876667
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Partial resistance to malonate-induced striatal cell death in transgenic mouse models of Huntington's disease is dependent on age and CAG repeat length.
    Hansson O; Castilho RF; Korhonen L; Lindholm D; Bates GP; Brundin P
    J Neurochem; 2001 Aug; 78(4):694-703. PubMed ID: 11520890
    [TBL] [Abstract][Full Text] [Related]  

  • 40. A Study of Triplet-Primed PCR for Identification of CAG Repeat Expansion in the HTT Gene in a Cohort of 503 Indian Cases with Huntington's Disease Symptoms.
    Chheda P; Chanekar M; Salunkhe Y; Dama T; Pais A; Pande S; Bendre R; Shah N
    Mol Diagn Ther; 2018 Jun; 22(3):353-359. PubMed ID: 29619771
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 28.