These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

189 related articles for article (PubMed ID: 22384276)

  • 1. Preventing phosphorylation of sterol regulatory element-binding protein 1a by MAP-kinases protects mice from fatty liver and visceral obesity.
    Kotzka J; Knebel B; Haas J; Kremer L; Jacob S; Hartwig S; Nitzgen U; Muller-Wieland D
    PLoS One; 2012; 7(2):e32609. PubMed ID: 22384276
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phosphorylation of sterol regulatory element-binding protein (SREBP)-1c by p38 kinases, ERK and JNK influences lipid metabolism and the secretome of human liver cell line HepG2.
    Knebel B; Lehr S; Hartwig S; Haas J; Kaber G; Dicken HD; Susanto F; Bohne L; Jacob S; Nitzgen U; Passlack W; Muller-Wieland D; Kotzka J
    Arch Physiol Biochem; 2014 Dec; 120(5):216-27. PubMed ID: 25353341
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inactivation of SREBP-1a Phosphorylation Prevents Fatty Liver Disease in Mice: Identification of Related Signaling Pathways by Gene Expression Profiles in Liver and Proteomes of Peroxisomes.
    Knebel B; Hartwig S; Jacob S; Kettel U; Schiller M; Passlack W; Koellmer C; Lehr S; Müller-Wieland D; Kotzka J
    Int J Mol Sci; 2018 Mar; 19(4):. PubMed ID: 29587401
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Lipid accumulation stimulates the cap-independent translation of SREBP-1a mRNA by promoting hnRNP A1 binding to its 5'-UTR in a cellular model of hepatic steatosis.
    Siculella L; Tocci R; Rochira A; Testini M; Gnoni A; Damiano F
    Biochim Biophys Acta; 2016 May; 1861(5):471-81. PubMed ID: 26869449
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Liver-specific expression of transcriptionally active SREBP-1c is associated with fatty liver and increased visceral fat mass.
    Knebel B; Haas J; Hartwig S; Jacob S; Köllmer C; Nitzgen U; Muller-Wieland D; Kotzka J
    PLoS One; 2012; 7(2):e31812. PubMed ID: 22363740
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Overexpression of sterol regulatory element-binding protein-1a in mouse adipose tissue produces adipocyte hypertrophy, increased fatty acid secretion, and fatty liver.
    Horton JD; Shimomura I; Ikemoto S; Bashmakov Y; Hammer RE
    J Biol Chem; 2003 Sep; 278(38):36652-60. PubMed ID: 12855691
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phosphorylation of sterol regulatory element-binding protein (SREBP)-1a links growth hormone action to lipid metabolism in hepatocytes.
    Kotzka J; Knebel B; Avci H; Jacob S; Nitzgen U; Jockenhovel F; Heeren J; Haas J; Muller-Wieland D
    Atherosclerosis; 2010 Nov; 213(1):156-65. PubMed ID: 20863500
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Sterol regulatory element binding proteins (SREBP)-1a and SREBP-2 are linked to the MAP-kinase cascade.
    Kotzka J; Müller-Wieland D; Roth G; Kremer L; Munck M; Schürmann S; Knebel B; Krone W
    J Lipid Res; 2000 Jan; 41(1):99-108. PubMed ID: 10627507
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a.
    Shimano H; Horton JD; Hammer RE; Shimomura I; Brown MS; Goldstein JL
    J Clin Invest; 1996 Oct; 98(7):1575-84. PubMed ID: 8833906
    [TBL] [Abstract][Full Text] [Related]  

  • 10. MAP kinases Erk1/2 phosphorylate sterol regulatory element-binding protein (SREBP)-1a at serine 117 in vitro.
    Roth G; Kotzka J; Kremer L; Lehr S; Lohaus C; Meyer HE; Krone W; Müller-Wieland D
    J Biol Chem; 2000 Oct; 275(43):33302-7. PubMed ID: 10915800
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sterol regulatory element-binding protein 1 is negatively modulated by PKA phosphorylation.
    Lu M; Shyy JY
    Am J Physiol Cell Physiol; 2006 Jun; 290(6):C1477-86. PubMed ID: 16381800
    [TBL] [Abstract][Full Text] [Related]  

  • 12. p38 mitogen-activated protein kinase and liver X receptor-α mediate the leptin effect on sterol regulatory element binding protein-1c expression in hepatic stellate cells.
    Yan K; Deng X; Zhai X; Zhou M; Jia X; Luo L; Niu M; Zhu H; Qiang H; Zhou Y
    Mol Med; 2012 Feb; 18(1):10-8. PubMed ID: 21979752
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Insulin-activated Erk-mitogen-activated protein kinases phosphorylate sterol regulatory element-binding Protein-2 at serine residues 432 and 455 in vivo.
    Kotzka J; Lehr S; Roth G; Avci H; Knebel B; Muller-Wieland D
    J Biol Chem; 2004 May; 279(21):22404-11. PubMed ID: 14988395
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 3,5-Diiodo-l-thyronine induces SREBP-1 proteolytic cleavage block and apoptosis in human hepatoma (Hepg2) cells.
    Rochira A; Damiano F; Marsigliante S; Gnoni GV; Siculella L
    Biochim Biophys Acta; 2013 Dec; 1831(12):1679-89. PubMed ID: 23948263
    [TBL] [Abstract][Full Text] [Related]  

  • 15. IGF-1 induces SREBP-1 expression and lipogenesis in SEB-1 sebocytes via activation of the phosphoinositide 3-kinase/Akt pathway.
    Smith TM; Gilliland K; Clawson GA; Thiboutot D
    J Invest Dermatol; 2008 May; 128(5):1286-93. PubMed ID: 17989724
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Lipogenic SREBP-1a/c transcription factors activate expression of the iron regulator hepcidin, revealing cross-talk between lipid and iron metabolisms.
    Xiaoli AM; Song Z; Yang F
    J Biol Chem; 2019 Aug; 294(34):12743-12753. PubMed ID: 31270208
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells.
    Shimano H; Horton JD; Shimomura I; Hammer RE; Brown MS; Goldstein JL
    J Clin Invest; 1997 Mar; 99(5):846-54. PubMed ID: 9062341
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A transcription factor of lipid synthesis, sterol regulatory element-binding protein (SREBP)-1a causes G(1) cell-cycle arrest after accumulation of cyclin-dependent kinase (cdk) inhibitors.
    Nakakuki M; Shimano H; Inoue N; Tamura M; Matsuzaka T; Nakagawa Y; Yahagi N; Toyoshima H; Sato R; Yamada N
    FEBS J; 2007 Sep; 274(17):4440-52. PubMed ID: 17662109
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sterol regulatory element-binding protein family as global regulators of lipid synthetic genes in energy metabolism.
    Shimano H
    Vitam Horm; 2002; 65():167-94. PubMed ID: 12481547
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Map4k4 suppresses Srebp-1 and adipocyte lipogenesis independent of JNK signaling.
    Danai LV; Guilherme A; Guntur KV; Straubhaar J; Nicoloro SM; Czech MP
    J Lipid Res; 2013 Oct; 54(10):2697-707. PubMed ID: 23924694
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.