BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

172 related articles for article (PubMed ID: 22391312)

  • 1. Aberrations and therapeutics involving the developmental pathway Hedgehog in pancreatic cancer.
    Kelleher FC; McDermott R
    Vitam Horm; 2012; 88():355-78. PubMed ID: 22391312
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Hedgehog signaling and therapeutics in pancreatic cancer.
    Kelleher FC
    Carcinogenesis; 2011 Apr; 32(4):445-51. PubMed ID: 21186299
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel neutralizing hedgehog antibody MEDI-5304 exhibits antitumor activity by inhibiting paracrine hedgehog signaling.
    Michaud NR; Wang Y; McEachern KA; Jordan JJ; Mazzola AM; Hernandez A; Jalla S; Chesebrough JW; Hynes MJ; Belmonte MA; Wang L; Kang JS; Jovanovic J; Laing N; Jenkins DW; Hurt E; Liang M; Frantz C; Hollingsworth RE; Simeone DM; Blakey DC; Bedian V
    Mol Cancer Ther; 2014 Feb; 13(2):386-98. PubMed ID: 24344235
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sonic hedgehog paracrine signaling activates stromal cells to promote perineural invasion in pancreatic cancer.
    Li X; Wang Z; Ma Q; Xu Q; Liu H; Duan W; Lei J; Ma J; Wang X; Lv S; Han L; Li W; Guo J; Guo K; Zhang D; Wu E; Xie K
    Clin Cancer Res; 2014 Aug; 20(16):4326-38. PubMed ID: 24947933
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Sonic hedgehog signaling inhibition provides opportunities for targeted therapy by sulforaphane in regulating pancreatic cancer stem cell self-renewal.
    Rodova M; Fu J; Watkins DN; Srivastava RK; Shankar S
    PLoS One; 2012; 7(9):e46083. PubMed ID: 23029396
    [TBL] [Abstract][Full Text] [Related]  

  • 6. TAK-441, a novel investigational smoothened antagonist, delays castration-resistant progression in prostate cancer by disrupting paracrine hedgehog signaling.
    Ibuki N; Ghaffari M; Pandey M; Iu I; Fazli L; Kashiwagi M; Tojo H; Nakanishi O; Gleave ME; Cox ME
    Int J Cancer; 2013 Oct; 133(8):1955-66. PubMed ID: 23564295
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Overexpression of Gremlin 1 by sonic hedgehog signaling promotes pancreatic cancer progression.
    Yu Y; Cheng L; Yan B; Zhou C; Qian W; Xiao Y; Qin T; Cao J; Han L; Ma Q; Ma J
    Int J Oncol; 2018 Dec; 53(6):2445-2457. PubMed ID: 30272371
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of hedgehog signaling depresses self-renewal of pancreatic cancer stem cells and reverses chemoresistance.
    Huang FT; Zhuan-Sun YX; Zhuang YY; Wei SL; Tang J; Chen WB; Zhang SN
    Int J Oncol; 2012 Nov; 41(5):1707-14. PubMed ID: 22923052
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Blockade of sonic hedgehog signal pathway enhances antiproliferative effect of EGFR inhibitor in pancreatic cancer cells.
    Hu WG; Liu T; Xiong JX; Wang CY
    Acta Pharmacol Sin; 2007 Aug; 28(8):1224-30. PubMed ID: 17640486
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of sonic hedgehog pathway and pluripotency maintaining factors regulate human pancreatic cancer stem cell characteristics.
    Tang SN; Fu J; Nall D; Rodova M; Shankar S; Srivastava RK
    Int J Cancer; 2012 Jul; 131(1):30-40. PubMed ID: 21796625
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Advances in Smoothened-targeting therapies for pancreatic cancer: implication for drug discovery from herbal medicines.
    Han JB; Hua YQ; Chen LY; Liu LM
    Zhong Xi Yi Jie He Xue Bao; 2012 Mar; 10(3):256-63. PubMed ID: 22409914
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PI3K/AKT/mTOR and sonic hedgehog pathways cooperate together to inhibit human pancreatic cancer stem cell characteristics and tumor growth.
    Sharma N; Nanta R; Sharma J; Gunewardena S; Singh KP; Shankar S; Srivastava RK
    Oncotarget; 2015 Oct; 6(31):32039-60. PubMed ID: 26451606
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of the hedgehog pathway targets the tumor-associated stroma in pancreatic cancer.
    Hwang RF; Moore TT; Hattersley MM; Scarpitti M; Yang B; Devereaux E; Ramachandran V; Arumugam T; Ji B; Logsdon CD; Brown JL; Godin R
    Mol Cancer Res; 2012 Sep; 10(9):1147-57. PubMed ID: 22859707
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis.
    Thayer SP; di Magliano MP; Heiser PW; Nielsen CM; Roberts DJ; Lauwers GY; Qi YP; Gysin S; Fernández-del Castillo C; Yajnik V; Antoniu B; McMahon M; Warshaw AL; Hebrok M
    Nature; 2003 Oct; 425(6960):851-6. PubMed ID: 14520413
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Blockade of hedgehog signaling pathway as a therapeutic strategy for pancreatic cancer.
    Xu FG; Ma QY; Wang Z
    Cancer Lett; 2009 Oct; 283(2):119-24. PubMed ID: 19232458
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Agents targeting the Hedgehog pathway for pancreatic cancer treatment.
    Bisht S; Brossart P; Maitra A; Feldmann G
    Curr Opin Investig Drugs; 2010 Dec; 11(12):1387-98. PubMed ID: 21154121
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sanguinarine inhibits pancreatic cancer stem cell characteristics by inducing oxidative stress and suppressing sonic hedgehog-Gli-Nanog pathway.
    Ma Y; Yu W; Shrivastava A; Alemi F; Lankachandra K; Srivastava RK; Shankar S
    Carcinogenesis; 2017 Oct; 38(10):1047-1056. PubMed ID: 28968696
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The hedgehog pathway and pancreatic cancer.
    Hidalgo M; Maitra A
    N Engl J Med; 2009 Nov; 361(21):2094-6. PubMed ID: 19923581
    [No Abstract]   [Full Text] [Related]  

  • 19. Hedgehog signaling and response to cyclopamine differ in epithelial and stromal cells in benign breast and breast cancer.
    Mukherjee S; Frolova N; Sadlonova A; Novak Z; Steg A; Page GP; Welch DR; Lobo-Ruppert SM; Ruppert JM; Johnson MR; Frost AR
    Cancer Biol Ther; 2006 Jun; 5(6):674-83. PubMed ID: 16855373
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Active sonic hedgehog signaling between androgen independent human prostate cancer cells and normal/benign but not cancer-associated prostate stromal cells.
    Shigemura K; Huang WC; Li X; Zhau HE; Zhu G; Gotoh A; Fujisawa M; Xie J; Marshall FF; Chung LW
    Prostate; 2011 Dec; 71(16):1711-22. PubMed ID: 21520153
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.