BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

193 related articles for article (PubMed ID: 22396725)

  • 21. Minimal requirement of tyrosine residues of linker for activation of T cells in TCR signaling and thymocyte development.
    Zhu M; Janssen E; Zhang W
    J Immunol; 2003 Jan; 170(1):325-33. PubMed ID: 12496416
    [TBL] [Abstract][Full Text] [Related]  

  • 22. The hematopoietic-specific adaptor protein gads functions in T-cell signaling via interactions with the SLP-76 and LAT adaptors.
    Liu SK; Fang N; Koretzky GA; McGlade CJ
    Curr Biol; 1999 Jan; 9(2):67-75. PubMed ID: 10021361
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Sos1 rapidly associates with Grb2 and is hypophosphorylated when complexed with the EGF receptor after EGF stimulation.
    Hu Y; Bowtell DD
    Oncogene; 1996 May; 12(9):1865-72. PubMed ID: 8649846
    [TBL] [Abstract][Full Text] [Related]  

  • 24. SH3 domains of Grb2 adaptor bind to PXpsiPXR motifs within the Sos1 nucleotide exchange factor in a discriminate manner.
    McDonald CB; Seldeen KL; Deegan BJ; Farooq A
    Biochemistry; 2009 May; 48(19):4074-85. PubMed ID: 19323566
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Grf40, A novel Grb2 family member, is involved in T cell signaling through interaction with SLP-76 and LAT.
    Asada H; Ishii N; Sasaki Y; Endo K; Kasai H; Tanaka N; Takeshita T; Tsuchiya S; Konno T; Sugamura K
    J Exp Med; 1999 May; 189(9):1383-90. PubMed ID: 10224278
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Identification of a new transmembrane adaptor protein that constitutively binds Grb2 in B cells.
    Liu Y; Zhang W
    J Leukoc Biol; 2008 Sep; 84(3):842-51. PubMed ID: 18559951
    [TBL] [Abstract][Full Text] [Related]  

  • 27. SOS1 interacts with Grb2 through regions that induce closed nSH3 conformations.
    Liao TJ; Jang H; Fushman D; Nussinov R
    J Chem Phys; 2020 Jul; 153(4):045106. PubMed ID: 32752665
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Multivalent binding and facilitated diffusion account for the formation of the Grb2-Sos1 signaling complex in a cooperative manner.
    McDonald CB; Balke JE; Bhat V; Mikles DC; Deegan BJ; Seldeen KL; Farooq A
    Biochemistry; 2012 Mar; 51(10):2122-35. PubMed ID: 22360309
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The importance of three membrane-distal tyrosines in the adaptor protein NTAL/LAB.
    Koonpaew S; Janssen E; Zhu M; Zhang W
    J Biol Chem; 2004 Mar; 279(12):11229-35. PubMed ID: 14722116
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Gads/Grb2-mediated association with LAT is critical for the inhibitory function of Gab2 in T cells.
    Yamasaki S; Nishida K; Sakuma M; Berry D; McGlade CJ; Hirano T; Saito T
    Mol Cell Biol; 2003 Apr; 23(7):2515-29. PubMed ID: 12640133
    [TBL] [Abstract][Full Text] [Related]  

  • 31. GrpL, a Grb2-related adaptor protein, interacts with SLP-76 to regulate nuclear factor of activated T cell activation.
    Law CL; Ewings MK; Chaudhary PM; Solow SA; Yun TJ; Marshall AJ; Hood L; Clark EA
    J Exp Med; 1999 Apr; 189(8):1243-53. PubMed ID: 10209041
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Sos-mediated activation of rac1 by p66shc.
    Khanday FA; Santhanam L; Kasuno K; Yamamori T; Naqvi A; Dericco J; Bugayenko A; Mattagajasingh I; Disanza A; Scita G; Irani K
    J Cell Biol; 2006 Mar; 172(6):817-22. PubMed ID: 16520382
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Regions outside of conserved PxxPxR motifs drive the high affinity interaction of GRB2 with SH3 domain ligands.
    Bartelt RR; Light J; Vacaflores A; Butcher A; Pandian M; Nash P; Houtman JC
    Biochim Biophys Acta; 2015 Oct; 1853(10 Pt A):2560-9. PubMed ID: 26079855
    [TBL] [Abstract][Full Text] [Related]  

  • 34. GRB2-mediated recruitment of THEMIS to LAT is essential for thymocyte development.
    Paster W; Brockmeyer C; Fu G; Simister PC; de Wet B; Martinez-Riaño A; Hoerter JA; Feller SM; Wülfing C; Gascoigne NR; Acuto O
    J Immunol; 2013 Apr; 190(7):3749-56. PubMed ID: 23460737
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Regulation of the adapter molecule Grb2 by the Fc epsilon R1 in the mast cell line RBL2H3.
    Turner H; Reif K; Rivera J; Cantrell DA
    J Biol Chem; 1995 Apr; 270(16):9500-6. PubMed ID: 7721878
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Bridging the Gap: Modulatory Roles of the Grb2-Family Adaptor, Gads, in Cellular and Allergic Immune Responses.
    Yablonski D
    Front Immunol; 2019; 10():1704. PubMed ID: 31402911
    [TBL] [Abstract][Full Text] [Related]  

  • 37. The transmembrane adapter LAT plays a central role in immune receptor signalling.
    Wonerow P; Watson SP
    Oncogene; 2001 Oct; 20(44):6273-83. PubMed ID: 11607829
    [TBL] [Abstract][Full Text] [Related]  

  • 38. SH3 domains of the adapter molecule Grb2 complex with two proteins in T cells: the guanine nucleotide exchange protein Sos and a 75-kDa protein that is a substrate for T cell antigen receptor-activated tyrosine kinases.
    Reif K; Buday L; Downward J; Cantrell DA
    J Biol Chem; 1994 May; 269(19):14081-7. PubMed ID: 8188688
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Shc contains two Grb2 binding sites needed for efficient formation of complexes with SOS in B lymphocytes.
    Harmer SL; DeFranco AL
    Mol Cell Biol; 1997 Jul; 17(7):4087-95. PubMed ID: 9199344
    [TBL] [Abstract][Full Text] [Related]  

  • 40. ShcA tyrosine phosphorylation sites can replace ShcA binding in signalling by middle T-antigen.
    Nicholson PR; Empereur S; Glover HR; Dilworth SM
    EMBO J; 2001 Nov; 20(22):6337-46. PubMed ID: 11707405
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.