185 related articles for article (PubMed ID: 22397403)
1. Contemporary challenges in the design of topoisomerase II inhibitors for cancer chemotherapy.
Bailly C
Chem Rev; 2012 Jul; 112(7):3611-40. PubMed ID: 22397403
[No Abstract] [Full Text] [Related]
2. Synthesis and evaluation of aroylthiourea derivatives of 4-β-amino-4'-O-demethyl-4-desoxypodophyllotoxin as novel topoisomerase II inhibitors.
Zhao Y; Ge CW; Wu ZH; Wang CN; Fang JH; Zhu L
Eur J Med Chem; 2011 Mar; 46(3):901-6. PubMed ID: 21277655
[TBL] [Abstract][Full Text] [Related]
3. An efficient one-pot synthesis of benzothiazolo-4β-anilino-podophyllotoxin congeners: DNA topoisomerase-II inhibition and anticancer activity.
Kamal A; Kumar BA; Suresh P; Shankaraiah N; Kumar MS
Bioorg Med Chem Lett; 2011 Jan; 21(1):350-3. PubMed ID: 21144748
[TBL] [Abstract][Full Text] [Related]
4. Synthesis of 4β-carbamoyl epipodophyllotoxins as potential antitumour agents.
Kamal A; Kumar BA; Suresh P; Juvekar A; Zingde S
Bioorg Med Chem; 2011 May; 19(9):2975-9. PubMed ID: 21489802
[TBL] [Abstract][Full Text] [Related]
5. Topoisomerase IIα, rather than IIβ, is a promising target in development of anti-cancer drugs.
Chen W; Qiu J; Shen YM
Drug Discov Ther; 2012 Oct; 6(5):230-7. PubMed ID: 23229142
[TBL] [Abstract][Full Text] [Related]
6. Synthesis of podophyllotoxin linked β-carboline congeners as potential anticancer agents and DNA topoisomerase II inhibitors.
Sathish M; Kavitha B; Nayak VL; Tangella Y; Ajitha A; Nekkanti S; Alarifi A; Shankaraiah N; Nagesh N; Kamal A
Eur J Med Chem; 2018 Jan; 144():557-571. PubMed ID: 29289881
[TBL] [Abstract][Full Text] [Related]
7. One-pot synthesis of podophyllotoxin-thiourea congeners by employing NH₂SO₃H/NaI: Anticancer activity, DNA topoisomerase-II inhibition, and apoptosis inducing agents.
Shankaraiah N; Kumar NP; Amula SB; Nekkanti S; Jeengar MK; Naidu VG; Reddy TS; Kamal A
Bioorg Med Chem Lett; 2015 Oct; 25(19):4239-44. PubMed ID: 26292628
[TBL] [Abstract][Full Text] [Related]
8. Design and synthesis of the novel DNA topoisomerase II inhibitors: esterification and amination substituted 4'-demethylepipodophyllotoxin derivates exhibiting anti-tumor activity by activating ATM/ATR signaling pathways.
Xiao L; Zhao W; Li HM; Wan DJ; Li DS; Chen T; Tang YJ
Eur J Med Chem; 2014 Jun; 80():267-77. PubMed ID: 24793877
[TBL] [Abstract][Full Text] [Related]
9. An optimized polyamine moiety boosts the potency of human type II topoisomerase poisons as quantified by comparative analysis centered on the clinical candidate F14512.
Palermo G; Minniti E; Greco ML; Riccardi L; Simoni E; Convertino M; Marchetti C; Rosini M; Sissi C; Minarini A; De Vivo M
Chem Commun (Camb); 2015 Oct; 51(76):14310-3. PubMed ID: 26234198
[TBL] [Abstract][Full Text] [Related]
10. Indenoindolone derivatives as topoisomerase II-inhibiting anticancer agents.
Kashyap M; Kandekar S; Baviskar AT; Das D; Preet R; Mohapatra P; Satapathy SR; Siddharth S; Guchhait SK; Kundu CN; Banerjee UC
Bioorg Med Chem Lett; 2013 Feb; 23(4):934-8. PubMed ID: 23321564
[TBL] [Abstract][Full Text] [Related]
11. Synthesis of 4β-N-polyaromatic substituted podophyllotoxins: DNA topoisomerase inhibition, anticancer and apoptosis-inducing activities.
Kamal A; Kumar BA; Suresh P; Agrawal SK; Chashoo G; Singh SK; Saxena AK
Bioorg Med Chem; 2010 Dec; 18(24):8493-500. PubMed ID: 21074444
[TBL] [Abstract][Full Text] [Related]
12. Identification of potent virtual leads and ADME prediction of isoxazolidine podophyllotoxin derivatives as topoisomerase II and tubulin inhibitors.
Bkhaitan MM; Mirza AZ; Shamshad H; Ali HI
J Mol Graph Model; 2017 May; 73():74-93. PubMed ID: 28242581
[TBL] [Abstract][Full Text] [Related]
13. The discovery and optimization of novel dual inhibitors of topoisomerase II and histone deacetylase.
Zhang X; Bao B; Yu X; Tong L; Luo Y; Huang Q; Su M; Sheng L; Li J; Zhu H; Yang B; Zhang X; Chen Y; Lu W
Bioorg Med Chem; 2013 Nov; 21(22):6981-95. PubMed ID: 24095018
[TBL] [Abstract][Full Text] [Related]
14. Cytotoxicity and cell death mechanisms induced by the polyamine-vectorized anti-cancer drug F14512 targeting topoisomerase II.
Brel V; Annereau JP; Vispé S; Kruczynski A; Bailly C; Guilbaud N
Biochem Pharmacol; 2011 Dec; 82(12):1843-52. PubMed ID: 21924246
[TBL] [Abstract][Full Text] [Related]
15. A novel epoxypropoxy flavonoid derivative and topoisomerase II inhibitor, MHY336, induces apoptosis in prostate cancer cells.
Patra N; De U; Kang JA; Kim JM; Ahn MY; Lee J; Jung JH; Chung HY; Moon HR; Kim HS
Eur J Pharmacol; 2011 May; 658(2-3):98-107. PubMed ID: 21376033
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and biological activities of topopyrones.
Zaleski PA; Maini R; Leiris SJ; Elban MA; Hecht SM
J Nat Prod; 2012 Apr; 75(4):577-85. PubMed ID: 22462811
[TBL] [Abstract][Full Text] [Related]
17. Pharmacophore Hybridization To Discover Novel Topoisomerase II Poisons with Promising Antiproliferative Activity.
Ortega JA; Riccardi L; Minniti E; Borgogno M; Arencibia JM; Greco ML; Minarini A; Sissi C; De Vivo M
J Med Chem; 2018 Feb; 61(3):1375-1379. PubMed ID: 29077404
[TBL] [Abstract][Full Text] [Related]
18. Regulation by survivin of cancer cell death induced by F14512, a polyamine-containing inhibitor of DNA topoisomerase II.
Ballot C; Jendoubi M; Kluza J; Jonneaux A; Laine W; Formstecher P; Bailly C; Marchetti P
Apoptosis; 2012 Apr; 17(4):364-76. PubMed ID: 22127645
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and evaluation of novel podophyllotoxin analogs.
Li J; Hua HM; Tang YB; Zhang S; Ohkoshi E; Lee KH; Xiao Zy
Bioorg Med Chem Lett; 2012 Jul; 22(13):4293-5. PubMed ID: 22658864
[TBL] [Abstract][Full Text] [Related]
20. Discovery of dihydroxylated 2,4-diphenyl-6-thiophen-2-yl-pyridine as a non-intercalative DNA-binding topoisomerase II-specific catalytic inhibitor.
Jun KY; Kwon H; Park SE; Lee E; Karki R; Thapa P; Lee JH; Lee ES; Kwon Y
Eur J Med Chem; 2014 Jun; 80():428-38. PubMed ID: 24796883
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]