104 related articles for article (PubMed ID: 22398221)
1. Gli inhibitor GANT61 causes apoptosis in myeloid leukemia cells and acts in synergy with rapamycin.
Pan D; Li Y; Li Z; Wang Y; Wang P; Liang Y
Leuk Res; 2012 Jun; 36(6):742-8. PubMed ID: 22398221
[TBL] [Abstract][Full Text] [Related]
2. Targeting GLI1 Suppresses Cell Growth and Enhances Chemosensitivity in CD34+ Enriched Acute Myeloid Leukemia Progenitor Cells.
Long B; Wang LX; Zheng FM; Lai SP; Xu DR; Hu Y; Lin DJ; Zhang XZ; Dong L; Long ZJ; Tong XZ; Liu Q
Cell Physiol Biochem; 2016; 38(4):1288-302. PubMed ID: 27008269
[TBL] [Abstract][Full Text] [Related]
3. Hh/Gli antagonist in acute myeloid leukemia with CBFA2T3-GLIS2 fusion gene.
Masetti R; Bertuccio SN; Astolfi A; Chiarini F; Lonetti A; Indio V; De Luca M; Bandini J; Serravalle S; Franzoni M; Pigazzi M; Martelli AM; Basso G; Locatelli F; Pession A
J Hematol Oncol; 2017 Jan; 10(1):26. PubMed ID: 28109323
[TBL] [Abstract][Full Text] [Related]
4. Targeting the hedgehog signal transduction pathway at the level of GLI inhibits neuroblastoma cell growth in vitro and in vivo.
Wickström M; Dyberg C; Shimokawa T; Milosevic J; Baryawno N; Fuskevåg OM; Larsson R; Kogner P; Zaphiropoulos PG; Johnsen JI
Int J Cancer; 2013 Apr; 132(7):1516-24. PubMed ID: 22949014
[TBL] [Abstract][Full Text] [Related]
5. Suppression of GLI sensitizes medulloblastoma cells to mitochondria-mediated apoptosis.
Lin Z; Li S; Sheng H; Cai M; Ma LY; Hu L; Xu S; Yu LS; Zhang N
J Cancer Res Clin Oncol; 2016 Dec; 142(12):2469-2478. PubMed ID: 27601167
[TBL] [Abstract][Full Text] [Related]
6. Inhibition of hedgehog signaling by GANT58 induces apoptosis and shows synergistic antitumor activity with AKT inhibitor in acute T cell leukemia cells.
Hou X; Chen X; Zhang P; Fan Y; Ma A; Pang T; Song Z; Jin Y; Hao W; Liu F; Wang W; Wang Y
Biochimie; 2014 Jun; 101():50-9. PubMed ID: 24394624
[TBL] [Abstract][Full Text] [Related]
7. Targeting GLI by GANT61 involves mechanisms dependent on inhibition of both transcription and DNA licensing.
Zhang R; Wu J; Ferrandon S; Glowacki KJ; Houghton JA
Oncotarget; 2016 Dec; 7(49):80190-80207. PubMed ID: 27863397
[TBL] [Abstract][Full Text] [Related]
8. Expression of Hedgehog Pathway Mediator GLI Represents a Negative Prognostic Marker in Human Acute Myeloid Leukemia and Its Inhibition Exerts Antileukemic Effects.
Wellbrock J; Latuske E; Köhler J; Wagner K; Stamm H; Vettorazzi E; Vohwinkel G; Klokow M; Uibeleisen R; Ehm P; Riecken K; Loges S; Thol F; Schubert C; Amling M; Jücker M; Bokemeyer C; Heuser M; Krauter J; Fiedler W
Clin Cancer Res; 2015 May; 21(10):2388-98. PubMed ID: 25745035
[TBL] [Abstract][Full Text] [Related]
9. Widespread Expression of Hedgehog Pathway Components in a Large Panel of Human Tumor Cells and Inhibition of Tumor Growth by GANT61: Implications for Cancer Therapy.
Réda J; Vachtenheim J; Vlčková K; Horák P; Vachtenheim J; Ondrušová L
Int J Mol Sci; 2018 Sep; 19(9):. PubMed ID: 30201866
[TBL] [Abstract][Full Text] [Related]
10. A Gli inhibitor GANT61 suppresses cell proliferation, promotes cell apoptosis and induces G1/G0 cycle retardation with a dose- and time-dependent manner through inhibiting Notch pathway in multiple myeloma.
Zhang Z; Hao C; Zhang R; Pei X; Li J; Wang L
Cell Cycle; 2020 Aug; 19(16):2063-2073. PubMed ID: 32677544
[TBL] [Abstract][Full Text] [Related]
11. HH/GLI signalling as a new therapeutic target for patients with oral squamous cell carcinoma.
Yan M; Wang L; Zuo H; Zhang Z; Chen W; Mao L; Zhang P
Oral Oncol; 2011 Jun; 47(6):504-9. PubMed ID: 21536478
[TBL] [Abstract][Full Text] [Related]
12. Hedgehog Signal Inhibitor GANT61 Inhibits the Malignant Behavior of Undifferentiated Hepatocellular Carcinoma Cells by Targeting Non-Canonical GLI Signaling.
Harada K; Ohashi R; Naito K; Kanki K
Int J Mol Sci; 2020 Apr; 21(9):. PubMed ID: 32354204
[TBL] [Abstract][Full Text] [Related]
13. ErbB2 signaling activates the Hedgehog pathway via PI3K-Akt in human esophageal adenocarcinoma: identification of novel targets for concerted therapy concepts.
Kebenko M; Drenckhan A; Gros SJ; Jücker M; Grabinski N; Ewald F; Grottke A; Schultze A; Izbicki JR; Bokemeyer C; Wellbrock J; Fiedler W
Cell Signal; 2015 Feb; 27(2):373-81. PubMed ID: 25435423
[TBL] [Abstract][Full Text] [Related]
14. GLI inhibitor GANT61 kills melanoma cells and acts in synergy with obatoclax.
Vlčková K; Réda J; Ondrušová L; Krayem M; Ghanem G; Vachtenheim J
Int J Oncol; 2016 Sep; 49(3):953-60. PubMed ID: 27572939
[TBL] [Abstract][Full Text] [Related]
15. Inhibition of GLI, but not Smoothened, induces apoptosis in chronic lymphocytic leukemia cells.
Desch P; Asslaber D; Kern D; Schnidar H; Mangelberger D; Alinger B; Stoecher M; Hofbauer SW; Neureiter D; Tinhofer I; Aberger F; Hartmann TN; Greil R
Oncogene; 2010 Sep; 29(35):4885-95. PubMed ID: 20603613
[TBL] [Abstract][Full Text] [Related]
16. Gli-1 expression is associated with lymph node metastasis and tumor progression in esophageal squamous cell carcinoma.
Mori Y; Okumura T; Tsunoda S; Sakai Y; Shimada Y
Oncology; 2006; 70(5):378-89. PubMed ID: 17179732
[TBL] [Abstract][Full Text] [Related]
17. Drug resistance is dramatically restored by hedgehog inhibitors in CD34+ leukemic cells.
Kobune M; Takimoto R; Murase K; Iyama S; Sato T; Kikuchi S; Kawano Y; Miyanishi K; Sato Y; Niitsu Y; Kato J
Cancer Sci; 2009 May; 100(5):948-55. PubMed ID: 19245435
[TBL] [Abstract][Full Text] [Related]
18. Targeting the hedgehog-glioma-associated oncogene homolog pathway inhibits bleomycin-induced lung fibrosis in mice.
Moshai EF; Wémeau-Stervinou L; Cigna N; Brayer S; Sommé JM; Crestani B; Mailleux AA
Am J Respir Cell Mol Biol; 2014 Jul; 51(1):11-25. PubMed ID: 24450438
[TBL] [Abstract][Full Text] [Related]
19. The GANT61, a GLI inhibitor, induces caspase-independent apoptosis of SK-N-LO cells.
Matsumoto T; Tabata K; Suzuki T
Biol Pharm Bull; 2014; 37(4):633-41. PubMed ID: 24694609
[TBL] [Abstract][Full Text] [Related]
20. Cyclopamine induces eosinophilic differentiation and upregulates CD44 expression in myeloid leukemia cells.
Takahashi T; Kawakami K; Mishima S; Akimoto M; Takenaga K; Suzumiya J; Honma Y
Leuk Res; 2011 May; 35(5):638-45. PubMed ID: 20971508
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]