BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

130 related articles for article (PubMed ID: 22399588)

  • 1. Ceramide synthase 6 knockdown suppresses apoptosis after photodynamic therapy in human head and neck squamous carcinoma cells.
    Separovic D; Breen P; Joseph N; Bielawski J; Pierce JS; VAN Buren E; Gudz TI
    Anticancer Res; 2012 Mar; 32(3):753-60. PubMed ID: 22399588
    [TBL] [Abstract][Full Text] [Related]  

  • 2. siRNA-mediated down-regulation of ceramide synthase 1 leads to apoptotic resistance in human head and neck squamous carcinoma cells after photodynamic therapy.
    Separovic D; Breen P; Joseph N; Bielawski J; Pierce JS; VAN Buren E; Gudz TI
    Anticancer Res; 2012 Jul; 32(7):2479-2485. PubMed ID: 22753704
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dihydroceramide desaturase knockdown impacts sphingolipids and apoptosis after photodamage in human head and neck squamous carcinoma cells.
    Breen P; Joseph N; Thompson K; Kraveka JM; Gudz TI; Li L; Rahmaniyan M; Bielawski J; Pierce JS; VAN Buren E; Bhatti G; Separovic D
    Anticancer Res; 2013 Jan; 33(1):77-84. PubMed ID: 23267130
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Enhanced killing of SCC17B human head and neck squamous cell carcinoma cells after photodynamic therapy plus fenretinide via the de novo sphingolipid biosynthesis pathway and apoptosis.
    Boppana NB; Stochaj U; Kodiha M; Bielawska A; Bielawski J; Pierce JS; Korbelik M; Separovic D
    Int J Oncol; 2015 May; 46(5):2003-10. PubMed ID: 25739041
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Increased killing of SCCVII squamous cell carcinoma cells after the combination of Pc 4 photodynamic therapy and dasatinib is associated with enhanced caspase-3 activity and ceramide synthase 1 upregulation.
    Separovic D; Breen P; Boppana NB; Van Buren E; Joseph N; Kraveka JM; Rahmaniyan M; Li L; Gudz TI; Bielawska A; Bai A; Bielawski J; Pierce JS; Korbelik M
    Int J Oncol; 2013 Dec; 43(6):2064-72. PubMed ID: 24126464
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Antiapoptotic roles of ceramide-synthase-6-generated C16-ceramide via selective regulation of the ATF6/CHOP arm of ER-stress-response pathways.
    Senkal CE; Ponnusamy S; Bielawski J; Hannun YA; Ogretmen B
    FASEB J; 2010 Jan; 24(1):296-308. PubMed ID: 19723703
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Monitoring ceramide and sphingosine-1-phosphate levels in cancer cells and macrophages from tumours treated by photodynamic therapy.
    Korbelik M; Zhang W; Separovic D
    Photochem Photobiol Sci; 2012 May; 11(5):779-84. PubMed ID: 22354109
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ceramide synthase inhibitor fumonisin B1 inhibits apoptotic cell death in SCC17B human head and neck squamous carcinoma cells after Pc4 photosensitization.
    Boppana NB; Kodiha M; Stochaj U; Lin HS; Haimovitz-Friedman A; Bielawska A; Bielawski J; Divine GW; Boyd JA; Korbelik M; Separovic D
    Photochem Photobiol Sci; 2014 Nov; 13(11):1621-7. PubMed ID: 25266739
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Developmentally regulated ceramide synthase 6 increases mitochondrial Ca2+ loading capacity and promotes apoptosis.
    Novgorodov SA; Chudakova DA; Wheeler BW; Bielawski J; Kindy MS; Obeid LM; Gudz TI
    J Biol Chem; 2011 Feb; 286(6):4644-58. PubMed ID: 21148554
    [TBL] [Abstract][Full Text] [Related]  

  • 10. C6-pyridinium ceramide sensitizes SCC17B human head and neck squamous cell carcinoma cells to photodynamic therapy.
    Boppana NB; Stochaj U; Kodiha M; Bielawska A; Bielawski J; Pierce JS; Korbelik M; Separovic D
    J Photochem Photobiol B; 2015 Feb; 143():163-8. PubMed ID: 25635908
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Amplification of cancer cell apoptosis in photodynamic therapy-treated tumors by adjuvant ceramide analog LCL29.
    Korbelik M; Zhang W; Separovic D
    Lasers Surg Med; 2011 Sep; 43(7):614-20. PubMed ID: 22057489
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Expression of Ceramide Synthase 6 Transcriptionally Activates Acid Ceramidase in a c-Jun N-terminal Kinase (JNK)-dependent Manner.
    Tirodkar TS; Lu P; Bai A; Scheffel MJ; Gencer S; Garrett-Mayer E; Bielawska A; Ogretmen B; Voelkel-Johnson C
    J Biol Chem; 2015 May; 290(21):13157-67. PubMed ID: 25839235
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Alteration of ceramide synthase 6/C16-ceramide induces activating transcription factor 6-mediated endoplasmic reticulum (ER) stress and apoptosis via perturbation of cellular Ca2+ and ER/Golgi membrane network.
    Senkal CE; Ponnusamy S; Manevich Y; Meyers-Needham M; Saddoughi SA; Mukhopadyay A; Dent P; Bielawski J; Ogretmen B
    J Biol Chem; 2011 Dec; 286(49):42446-42458. PubMed ID: 22013072
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Combining anticancer agents photodynamic therapy and LCL85 leads to distinct changes in the sphingolipid profile, autophagy, caspase-3 activation in the absence of cell death, and long-term sensitization.
    Separovic D; Joseph N; Breen P; Bielawski J; Pierce JS; Buren EV; Bhatti G; Saad ZH; Bai A; Bielawska A
    Biochem Biophys Res Commun; 2011 Jun; 409(3):372-7. PubMed ID: 21545791
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ceramide synthase-6 confers resistance to chemotherapy by binding to CD95/Fas in T-cell acute lymphoblastic leukemia.
    Verlekar D; Wei SJ; Cho H; Yang S; Kang MH
    Cell Death Dis; 2018 Sep; 9(9):925. PubMed ID: 30206207
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Fumonisin B1 Inhibits Endoplasmic Reticulum Stress Associated-apoptosis After FoscanPDT Combined with C6-Pyridinium Ceramide or Fenretinide.
    Boppana NB; Kraveka JM; Rahmaniyan M; Li LI; Bielawska A; Bielawski J; Pierce JS; Delor JS; Zhang K; Korbelik M; Separovic D
    Anticancer Res; 2017 Feb; 37(2):455-463. PubMed ID: 28179290
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Enhanced apoptotic cancer cell killing after Foscan photodynamic therapy combined with fenretinide via de novo sphingolipid biosynthesis pathway.
    Boppana NB; DeLor JS; Van Buren E; Bielawska A; Bielawski J; Pierce JS; Korbelik M; Separovic D
    J Photochem Photobiol B; 2016 Jun; 159():191-5. PubMed ID: 27085050
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The role of C16:0 ceramide in the development of obesity and type 2 diabetes: CerS6 inhibition as a novel therapeutic approach.
    Raichur S; Brunner B; Bielohuby M; Hansen G; Pfenninger A; Wang B; Bruning JC; Larsen PJ; Tennagels N
    Mol Metab; 2019 Mar; 21():36-50. PubMed ID: 30655217
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Enhanced tumor cures after Foscan photodynamic therapy combined with the ceramide analog LCL29. Evidence from mouse squamous cell carcinomas for sphingolipids as biomarkers of treatment response.
    Separovic D; Bielawski J; Pierce JS; Merchant S; Tarca AL; Bhatti G; Ogretmen B; Korbelik M
    Int J Oncol; 2011 Feb; 38(2):521-7. PubMed ID: 21152858
    [TBL] [Abstract][Full Text] [Related]  

  • 20. CerS6 regulates cisplatin resistance in oral squamous cell carcinoma by altering mitochondrial fission and autophagy.
    Li S; Wu Y; Ding Y; Yu M; Ai Z
    J Cell Physiol; 2018 Dec; 233(12):9416-9425. PubMed ID: 30054909
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.