BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

258 related articles for article (PubMed ID: 22409228)

  • 1. A paradigm for enzyme-catalyzed proton transfer at carbon: triosephosphate isomerase.
    Richard JP
    Biochemistry; 2012 Apr; 51(13):2652-61. PubMed ID: 22409228
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Specificity in transition state binding: the Pauling model revisited.
    Amyes TL; Richard JP
    Biochemistry; 2013 Mar; 52(12):2021-35. PubMed ID: 23327224
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Linear Free Energy Relationships for Enzymatic Reactions: Fresh Insight from a Venerable Probe.
    Richard JP; Cristobal JR; Amyes TL
    Acc Chem Res; 2021 May; 54(10):2532-2542. PubMed ID: 33939414
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Wildtype and engineered monomeric triosephosphate isomerase from Trypanosoma brucei: partitioning of reaction intermediates in D2O and activation by phosphite dianion.
    Malabanan MM; Go MK; Amyes TL; Richard JP
    Biochemistry; 2011 Jun; 50(25):5767-79. PubMed ID: 21553855
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Enzymatic catalysis of proton transfer at carbon: activation of triosephosphate isomerase by phosphite dianion.
    Amyes TL; Richard JP
    Biochemistry; 2007 May; 46(19):5841-54. PubMed ID: 17444661
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mechanism for activation of triosephosphate isomerase by phosphite dianion: the role of a hydrophobic clamp.
    Malabanan MM; Koudelka AP; Amyes TL; Richard JP
    J Am Chem Soc; 2012 Jun; 134(24):10286-98. PubMed ID: 22583393
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Uncovering the Role of Key Active-Site Side Chains in Catalysis: An Extended Brønsted Relationship for Substrate Deprotonation Catalyzed by Wild-Type and Variants of Triosephosphate Isomerase.
    Kulkarni YS; Amyes TL; Richard JP; Kamerlin SCL
    J Am Chem Soc; 2019 Oct; 141(40):16139-16150. PubMed ID: 31508957
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Reflections on the catalytic power of a TIM-barrel.
    Richard JP; Zhai X; Malabanan MM
    Bioorg Chem; 2014 Dec; 57():206-212. PubMed ID: 25092608
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mechanism for activation of triosephosphate isomerase by phosphite dianion: the role of a ligand-driven conformational change.
    Malabanan MM; Amyes TL; Richard JP
    J Am Chem Soc; 2011 Oct; 133(41):16428-31. PubMed ID: 21939233
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Role of Lys-12 in catalysis by triosephosphate isomerase: a two-part substrate approach.
    Go MK; Koudelka A; Amyes TL; Richard JP
    Biochemistry; 2010 Jun; 49(25):5377-89. PubMed ID: 20481463
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Enzyme architecture: the effect of replacement and deletion mutations of loop 6 on catalysis by triosephosphate isomerase.
    Zhai X; Go MK; O'Donoghue AC; Amyes TL; Pegan SD; Wang Y; Loria JP; Mesecar AD; Richard JP
    Biochemistry; 2014 Jun; 53(21):3486-501. PubMed ID: 24825099
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hydron transfer catalyzed by triosephosphate isomerase. Products of isomerization of (R)-glyceraldehyde 3-phosphate in D2O.
    O'Donoghue AC; Amyes TL; Richard JP
    Biochemistry; 2005 Feb; 44(7):2610-21. PubMed ID: 15709774
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mechanistic Imperatives for Deprotonation of Carbon Catalyzed by Triosephosphate Isomerase: Enzyme-Activation by Phosphite Dianion.
    Zhai X; Malabanan MM; Amyes TL; Richard JP
    J Phys Org Chem; 2014 Apr; 27(4):269-276. PubMed ID: 24729658
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Proton transfer in the mechanism of triosephosphate isomerase.
    Harris TK; Cole RN; Comer FI; Mildvan AS
    Biochemistry; 1998 Nov; 37(47):16828-38. PubMed ID: 9843453
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure of the triosephosphate isomerase-phosphoglycolohydroxamate complex: an analogue of the intermediate on the reaction pathway.
    Davenport RC; Bash PA; Seaton BA; Karplus M; Petsko GA; Ringe D
    Biochemistry; 1991 Jun; 30(24):5821-6. PubMed ID: 2043623
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Enzyme Architecture: Modeling the Operation of a Hydrophobic Clamp in Catalysis by Triosephosphate Isomerase.
    Kulkarni YS; Liao Q; Petrović D; Krüger DM; Strodel B; Amyes TL; Richard JP; Kamerlin SCL
    J Am Chem Soc; 2017 Aug; 139(30):10514-10525. PubMed ID: 28683550
    [TBL] [Abstract][Full Text] [Related]  

  • 17. NMR studies of the role of hydrogen bonding in the mechanism of triosephosphate isomerase.
    Harris TK; Abeygunawardana C; Mildvan AS
    Biochemistry; 1997 Dec; 36(48):14661-75. PubMed ID: 9398185
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Role of Ligand-Driven Conformational Changes in Enzyme Catalysis: Modeling the Reactivity of the Catalytic Cage of Triosephosphate Isomerase.
    Kulkarni YS; Liao Q; Byléhn F; Amyes TL; Richard JP; Kamerlin SCL
    J Am Chem Soc; 2018 Mar; 140(11):3854-3857. PubMed ID: 29516737
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural mutations that probe the interactions between the catalytic and dianion activation sites of triosephosphate isomerase.
    Zhai X; Amyes TL; Wierenga RK; Loria JP; Richard JP
    Biochemistry; 2013 Aug; 52(34):5928-40. PubMed ID: 23909928
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ab initio models for receptor-ligand interactions in proteins. 4. Model assembly study of the catalytic mechanism of triosephosphate isomerase.
    Peräkylä M; Pakkanen TA
    Proteins; 1996 Jun; 25(2):225-36. PubMed ID: 8811738
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.