238 related articles for article (PubMed ID: 22409549)
1. Application of LC-high-resolution MS with 'intelligent' data mining tools for screening reactive drug metabolites.
Ma S; Chowdhury SK
Bioanalysis; 2012 Mar; 4(5):501-10. PubMed ID: 22409549
[TBL] [Abstract][Full Text] [Related]
2. Recent advances in applications of liquid chromatography-tandem mass spectrometry to the analysis of reactive drug metabolites.
Ma S; Zhu M
Chem Biol Interact; 2009 Apr; 179(1):25-37. PubMed ID: 18848531
[TBL] [Abstract][Full Text] [Related]
3. High-resolution chromatography/time-of-flight MSE with in silico data mining is an information-rich approach to reactive metabolite screening.
Barbara JE; Castro-Perez JM
Rapid Commun Mass Spectrom; 2011 Oct; 25(20):3029-40. PubMed ID: 21953957
[TBL] [Abstract][Full Text] [Related]
4. Automatic mass spectrometry method development for drug discovery: application in metabolic stability assays.
Chovan LE; Black-Schaefer C; Dandliker PJ; Lau YY
Rapid Commun Mass Spectrom; 2004; 18(24):3105-12. PubMed ID: 15565734
[TBL] [Abstract][Full Text] [Related]
5. Accelerated throughput metabolic route screening in early drug discovery using high-resolution liquid chromatography/quadrupole time-of-flight mass spectrometry and automated data analysis.
Mortishire-Smith RJ; O'Connor D; Castro-Perez JM; Kirby J
Rapid Commun Mass Spectrom; 2005; 19(18):2659-70. PubMed ID: 16124034
[TBL] [Abstract][Full Text] [Related]
6. Current and future trends in the application of HPLC-MS to metabolite-identification studies.
Castro-Perez JM
Drug Discov Today; 2007 Mar; 12(5-6):249-56. PubMed ID: 17331890
[TBL] [Abstract][Full Text] [Related]
7. Liquid chromatography/atmospheric pressure ionization-mass spectrometry in drug metabolism studies.
Kostiainen R; Kotiaho T; Kuuranne T; Auriola S
J Mass Spectrom; 2003 Apr; 38(4):357-72. PubMed ID: 12717747
[TBL] [Abstract][Full Text] [Related]
8. Liquid chromatography-mass spectrometry in in vitro drug metabolite screening.
Tolonen A; Turpeinen M; Pelkonen O
Drug Discov Today; 2009 Feb; 14(3-4):120-33. PubMed ID: 19059358
[TBL] [Abstract][Full Text] [Related]
9. Characterization of cyanide-trapped methylated metabonates formed during reactive drug metabolite screening in vitro.
Rousu T; Tolonen A
Rapid Commun Mass Spectrom; 2011 May; 25(10):1382-90. PubMed ID: 21504003
[TBL] [Abstract][Full Text] [Related]
10. Detecting and characterizing reactive metabolites by liquid chromatography/tandem mass spectrometry.
Ma S; Subramanian R
J Mass Spectrom; 2006 Sep; 41(9):1121-39. PubMed ID: 16967439
[TBL] [Abstract][Full Text] [Related]
11. Improved detection of reactive metabolites with a bromine-containing glutathione analog using mass defect and isotope pattern matching.
Leblanc A; Shiao TC; Roy R; Sleno L
Rapid Commun Mass Spectrom; 2010 May; 24(9):1241-50. PubMed ID: 20391594
[TBL] [Abstract][Full Text] [Related]
12. Data acquisition and data mining techniques for metabolite identification using LC coupled to high-resolution MS.
Ma S; Chowdhury SK
Bioanalysis; 2013 May; 5(10):1285-97. PubMed ID: 23721449
[TBL] [Abstract][Full Text] [Related]
13. Screening for pharmaco-toxicologically relevant compounds in biosamples using high-resolution mass spectrometry: a 'metabolomic' approach to the discrimination between isomers.
Liotta E; Gottardo R; Bertaso A; Polettini A
J Mass Spectrom; 2010 Mar; 45(3):261-71. PubMed ID: 20014151
[TBL] [Abstract][Full Text] [Related]
14. Addressing the analytical throughput challenges in ADME screening using rapid ultra-performance liquid chromatography/tandem mass spectrometry methodologies.
Plumb RS; Potts WB; Rainville PD; Alden PG; Shave DH; Baynham G; Mazzeo JR
Rapid Commun Mass Spectrom; 2008 Jul; 22(14):2139-52. PubMed ID: 18543375
[TBL] [Abstract][Full Text] [Related]
15. The impact of recent innovations in the use of liquid chromatography-mass spectrometry in support of drug metabolism studies: are we all the way there yet?
Nassar AE; Talaat RE; Kamel AM
Curr Opin Drug Discov Devel; 2006 Jan; 9(1):61-74. PubMed ID: 16445118
[TBL] [Abstract][Full Text] [Related]
16. Application of on-line nano-liquid chromatography/mass spectrometry in metabolite identification studies.
Liu J; Zhao Z; Teffera Y
Rapid Commun Mass Spectrom; 2012 Feb; 26(3):320-6. PubMed ID: 22223319
[TBL] [Abstract][Full Text] [Related]
17. Approaches to the assessment of stable and chemically reactive drug metabolites in early clinical trials.
Baillie TA
Chem Res Toxicol; 2009 Feb; 22(2):263-6. PubMed ID: 19216579
[TBL] [Abstract][Full Text] [Related]
18. A novel approach to perform metabolite screening during the quantitative LC-MS/MS analyses of in vitro metabolic stability samples using a hybrid triple-quadrupole linear ion trap mass spectrometer.
Shou WZ; Magis L; Li AC; Naidong W; Bryant MS
J Mass Spectrom; 2005 Oct; 40(10):1347-56. PubMed ID: 16206149
[TBL] [Abstract][Full Text] [Related]
19. Screening and characterization of reactive compounds with in vitro peptide-trapping and liquid chromatography/high-resolution accurate mass spectrometry.
Wei C; Chupak LS; Philip T; Johnson BM; Gentles R; Drexler DM
J Biomol Screen; 2014 Feb; 19(2):297-307. PubMed ID: 23796688
[TBL] [Abstract][Full Text] [Related]
20. Recent development in software and automation tools for high-throughput discovery bioanalysis.
Shou WZ; Zhang J
Bioanalysis; 2012 May; 4(9):1097-109. PubMed ID: 22612689
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
