158 related articles for article (PubMed ID: 22411993)
1. Sequences flanking Arg336 in factor VIIIa modulate factor Xa-catalyzed cleavage rates at this site and cofactor function.
DeAngelis JP; Wakabayashi H; Fay PJ
J Biol Chem; 2012 May; 287(19):15409-17. PubMed ID: 22411993
[TBL] [Abstract][Full Text] [Related]
2. The role of P4-P3' residues flanking Arg336 in facilitating activated protein C-catalyzed cleavage and inactivation of factor VIIIa.
DeAngelis JP; Varfaj F; Wakabayashi H; Fay PJ
Thromb Res; 2011 Nov; 128(5):470-6. PubMed ID: 21470668
[TBL] [Abstract][Full Text] [Related]
3. Residues flanking scissile bonds in Factor VIII modulate rates of cleavage and proteolytic activation catalyzed by Factor Xa.
Griffiths AE; Wintermute J; Newell-Caito JL; Fay PJ
Biochemistry; 2013 Nov; 52(45):8060-8. PubMed ID: 24128092
[TBL] [Abstract][Full Text] [Related]
4. Combining mutations that modulate inter-subunit interactions and proteolytic inactivation enhance the stability of factor VIIIa.
Wakabayashi H; Wintermute JM; Fay PJ
Thromb Haemost; 2014 Jul; 112(1):43-52. PubMed ID: 24599523
[TBL] [Abstract][Full Text] [Related]
5. P3-P3' residues flanking scissile bonds in factor VIII modulate rates of substrate cleavage and procofactor activation by thrombin.
Newell-Caito JL; Griffiths AE; Fay PJ
Biochemistry; 2012 Apr; 51(16):3451-9. PubMed ID: 22455313
[TBL] [Abstract][Full Text] [Related]
6. Residues surrounding Arg336 and Arg562 contribute to the disparate rates of proteolysis of factor VIIIa catalyzed by activated protein C.
Varfaj F; Wakabayashi H; Fay PJ
J Biol Chem; 2007 Jul; 282(28):20264-72. PubMed ID: 17519239
[TBL] [Abstract][Full Text] [Related]
7. Contribution of factor VIII light-chain residues 2007-2016 to an activated protein C-interactive site.
Takeyama M; Wakabayashi H; Fay PJ
Thromb Haemost; 2013 Feb; 109(2):187-98. PubMed ID: 23224054
[TBL] [Abstract][Full Text] [Related]
8. An in silico and in vitro approach to elucidate the impact of residues flanking the cleavage scissile bonds of FVIII.
Pezeshkpoor B; Schreck U; Biswas A; Driesen J; Berkemeier AC; Pavlova A; Müller J; Oldenburg J
PLoS One; 2017; 12(7):e0180456. PubMed ID: 28683085
[TBL] [Abstract][Full Text] [Related]
9. Acidic Region Residues 1680-1684 in the A3 Domain of Factor VIII Contain a Thrombin-Interactive Site Responsible for Proteolytic Cleavage at Arg1689.
Nakajima Y; Minami H; Nogami K
Thromb Haemost; 2021 Oct; 121(10):1274-1288. PubMed ID: 33592631
[TBL] [Abstract][Full Text] [Related]
10. Role of P1 residues Arg336 and Arg562 in the activated-Protein-C-catalysed inactivation of Factor VIIIa.
Varfaj F; Neuberg J; Jenkins PV; Wakabayashi H; Fay PJ
Biochem J; 2006 Jun; 396(2):355-62. PubMed ID: 16503879
[TBL] [Abstract][Full Text] [Related]
11. Proteolysis at Arg740 facilitates subsequent bond cleavages during thrombin-catalyzed activation of factor VIII.
Newell JL; Fay PJ
J Biol Chem; 2007 Aug; 282(35):25367-75. PubMed ID: 17595160
[TBL] [Abstract][Full Text] [Related]
12. Mechanisms of factor Xa-catalyzed cleavage of the factor VIIIa A1 subunit resulting in cofactor inactivation.
Nogami K; Wakabayashi H; Fay PJ
J Biol Chem; 2003 May; 278(19):16502-9. PubMed ID: 12606556
[TBL] [Abstract][Full Text] [Related]
13. Activated factor X cleaves factor VIII at arginine 562, limiting its cofactor efficiency.
Plantier JL; Rolli V; Ducasse C; Dargaud Y; Enjolras N; Boukerche H; Négrier C
J Thromb Haemost; 2010 Feb; 8(2):286-93. PubMed ID: 19874476
[TBL] [Abstract][Full Text] [Related]
14. Characterisation of an antibody specific for coagulation factor VIII that enhances factor VIII activity.
Takeyama M; Nogami K; Matsumoto T; Soeda T; Suzuki T; Hattori K; Shima M
Thromb Haemost; 2010 Jan; 103(1):94-102. PubMed ID: 20062922
[TBL] [Abstract][Full Text] [Related]
15. Variable contributions of basic residues forming an APC exosite in the binding and inactivation of factor VIIIa.
Takeyama M; Wintermute JM; Manithody C; Rezaie AR; Fay PJ
Biochemistry; 2013 Apr; 52(13):2228-35. PubMed ID: 23480827
[TBL] [Abstract][Full Text] [Related]
16. Cleavage at Arg-1689 influences heavy chain cleavages during thrombin-catalyzed activation of factor VIII.
Newell JL; Fay PJ
J Biol Chem; 2009 Apr; 284(17):11080-9. PubMed ID: 19240027
[TBL] [Abstract][Full Text] [Related]
17. The C-terminal region of the factor V B-domain is crucial for the anticoagulant activity of factor V.
Thorelli E; Kaufman RJ; Dahlbäck B
J Biol Chem; 1998 Jun; 273(26):16140-5. PubMed ID: 9632668
[TBL] [Abstract][Full Text] [Related]
18. Characterization of a factor Xa binding site on factor Va near the Arg-506 activated protein C cleavage site.
Gale AJ; Yegneswaran S; Xu X; Pellequer JL; Griffin JH
J Biol Chem; 2007 Jul; 282(30):21848-55. PubMed ID: 17553804
[TBL] [Abstract][Full Text] [Related]
19. Mild hemophilia A caused by increased rate of factor VIII A2 subunit dissociation: evidence for nonproteolytic inactivation of factor VIIIa in vivo.
Pipe SW; Eickhorst AN; McKinley SH; Saenko EL; Kaufman RJ
Blood; 1999 Jan; 93(1):176-83. PubMed ID: 9864159
[TBL] [Abstract][Full Text] [Related]
20. Interaction of the 268-282 region of glycoprotein Ibalpha with the heparin-binding site of thrombin inhibits the enzyme activation of factor VIII.
De Cristofaro R; De Filippis V
Biochem J; 2003 Jul; 373(Pt 2):593-601. PubMed ID: 12689334
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]