These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

553 related articles for article (PubMed ID: 22416140)

  • 1. SIRT3 protein deacetylates isocitrate dehydrogenase 2 (IDH2) and regulates mitochondrial redox status.
    Yu W; Dittenhafer-Reed KE; Denu JM
    J Biol Chem; 2012 Apr; 287(17):14078-86. PubMed ID: 22416140
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction.
    Someya S; Yu W; Hallows WC; Xu J; Vann JM; Leeuwenburgh C; Tanokura M; Denu JM; Prolla TA
    Cell; 2010 Nov; 143(5):802-12. PubMed ID: 21094524
    [TBL] [Abstract][Full Text] [Related]  

  • 3. SIRT3 and GCN5L regulation of NADP+- and NADPH-driven reactions of mitochondrial isocitrate dehydrogenase IDH2.
    Smolková K; Špačková J; Gotvaldová K; Dvořák A; Křenková A; Hubálek M; Holendová B; Vítek L; Ježek P
    Sci Rep; 2020 May; 10(1):8677. PubMed ID: 32457458
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Overexpression of Sirt3 inhibits lipid accumulation in macrophages through mitochondrial IDH2 deacetylation.
    Sheng S; Kang Y; Guo Y; Pu Q; Cai M; Tu Z
    Int J Clin Exp Pathol; 2015; 8(8):9196-201. PubMed ID: 26464666
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hypertrophic preconditioning attenuates post-myocardial infarction injury through deacetylation of isocitrate dehydrogenase 2.
    Ma LL; Kong FJ; Ma YJ; Guo JJ; Wang SJ; Dong Z; Sun AJ; Zou YZ; Ge JB
    Acta Pharmacol Sin; 2021 Dec; 42(12):2004-2015. PubMed ID: 34163022
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hypertrophic preconditioning attenuates myocardial ischemia/reperfusion injury through the deacetylation of isocitrate dehydrogenase 2.
    Ma L; Shi H; Li Y; Gao W; Guo J; Zhu J; Dong Z; Sun A; Zou Y; Ge J
    Sci Bull (Beijing); 2021 Oct; 66(20):2099-2114. PubMed ID: 36654268
    [TBL] [Abstract][Full Text] [Related]  

  • 7. SIRT3 deacetylates FOXO3 to protect mitochondria against oxidative damage.
    Tseng AH; Shieh SS; Wang DL
    Free Radic Biol Med; 2013 Oct; 63():222-34. PubMed ID: 23665396
    [TBL] [Abstract][Full Text] [Related]  

  • 8. SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation.
    Hirschey MD; Shimazu T; Goetzman E; Jing E; Schwer B; Lombard DB; Grueter CA; Harris C; Biddinger S; Ilkayeva OR; Stevens RD; Li Y; Saha AK; Ruderman NB; Bain JR; Newgard CB; Farese RV; Alt FW; Kahn CR; Verdin E
    Nature; 2010 Mar; 464(7285):121-5. PubMed ID: 20203611
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mitochondrial NADP
    Kong MJ; Han SJ; Kim JI; Park JW; Park KM
    Cell Death Dis; 2018 May; 9(5):488. PubMed ID: 29695796
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Therapeutic potential of the mitochondria-targeted antioxidant MitoQ in mitochondrial-ROS induced sensorineural hearing loss caused by Idh2 deficiency.
    Kim YR; Baek JI; Kim SH; Kim MA; Lee B; Ryu N; Kim KH; Choi DG; Kim HM; Murphy MP; Macpherson G; Choo YS; Bok J; Lee KY; Park JW; Kim UK
    Redox Biol; 2019 Jan; 20():544-555. PubMed ID: 30508699
    [TBL] [Abstract][Full Text] [Related]  

  • 11. SIRT3-Mediated Dimerization of IDH2 Directs Cancer Cell Metabolism and Tumor Growth.
    Zou X; Zhu Y; Park SH; Liu G; O'Brien J; Jiang H; Gius D
    Cancer Res; 2017 Aug; 77(15):3990-3999. PubMed ID: 28536275
    [TBL] [Abstract][Full Text] [Related]  

  • 12. SIRT5 promotes IDH2 desuccinylation and G6PD deglutarylation to enhance cellular antioxidant defense.
    Zhou L; Wang F; Sun R; Chen X; Zhang M; Xu Q; Wang Y; Wang S; Xiong Y; Guan KL; Yang P; Yu H; Ye D
    EMBO Rep; 2016 Jun; 17(6):811-22. PubMed ID: 27113762
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5.
    Schlicker C; Gertz M; Papatheodorou P; Kachholz B; Becker CF; Steegborn C
    J Mol Biol; 2008 Oct; 382(3):790-801. PubMed ID: 18680753
    [TBL] [Abstract][Full Text] [Related]  

  • 14.
    Park JH; Ku HJ; Lee JH; Park JW
    Oxid Med Cell Longev; 2017; 2017():1595103. PubMed ID: 29456784
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Loss of SIRT3 Provides Growth Advantage for B Cell Malignancies.
    Yu W; Denu RA; Krautkramer KA; Grindle KM; Yang DT; Asimakopoulos F; Hematti P; Denu JM
    J Biol Chem; 2016 Feb; 291(7):3268-79. PubMed ID: 26631723
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Studies on the regulatory mechanism of isocitrate dehydrogenase 2 using acetylation mimics.
    Xu Y; Liu L; Nakamura A; Someya S; Miyakawa T; Tanokura M
    Sci Rep; 2017 Aug; 7(1):9785. PubMed ID: 28852116
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction.
    Hallows WC; Yu W; Smith BC; Devries MK; Ellinger JJ; Someya S; Shortreed MR; Prolla T; Markley JL; Smith LM; Zhao S; Guan KL; Denu JM
    Mol Cell; 2011 Jan; 41(2):139-49. PubMed ID: 21255725
    [TBL] [Abstract][Full Text] [Related]  

  • 18. SIRT3 deacetylated and increased citrate synthase activity in PD model.
    Cui XX; Li X; Dong SY; Guo YJ; Liu T; Wu YC
    Biochem Biophys Res Commun; 2017 Mar; 484(4):767-773. PubMed ID: 28161643
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sirtuin 3 (SIRT3) protein regulates long-chain acyl-CoA dehydrogenase by deacetylating conserved lysines near the active site.
    Bharathi SS; Zhang Y; Mohsen AW; Uppala R; Balasubramani M; Schreiber E; Uechi G; Beck ME; Rardin MJ; Vockley J; Verdin E; Gibson BW; Hirschey MD; Goetzman ES
    J Biol Chem; 2013 Nov; 288(47):33837-33847. PubMed ID: 24121500
    [TBL] [Abstract][Full Text] [Related]  

  • 20. SUMOylation enhances the activity of IDH2 under oxidative stress.
    Yu Y; Chen Y; Liu K; Cheng J; Tu J
    Biochem Biophys Res Commun; 2020 Nov; 532(4):591-597. PubMed ID: 32900482
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 28.