625 related articles for article (PubMed ID: 22420752)
1. Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2,4-pyridine-dicarboxylic acid as an in vitro and in cell inhibitor.
Kristensen LH; Nielsen AL; Helgstrand C; Lees M; Cloos P; Kastrup JS; Helin K; Olsen L; Gajhede M
FEBS J; 2012 Jun; 279(11):1905-14. PubMed ID: 22420752
[TBL] [Abstract][Full Text] [Related]
2. Catalytic properties and kinetic mechanism of human recombinant Lys-9 histone H3 methyltransferase SUV39H1: participation of the chromodomain in enzymatic catalysis.
Chin HG; Patnaik D; Estève PO; Jacobsen SE; Pradhan S
Biochemistry; 2006 Mar; 45(10):3272-84. PubMed ID: 16519522
[TBL] [Abstract][Full Text] [Related]
3. SUMOylation negatively modulates target gene occupancy of the KDM5B, a histone lysine demethylase.
Bueno MT; Richard S
Epigenetics; 2013 Nov; 8(11):1162-75. PubMed ID: 23970103
[TBL] [Abstract][Full Text] [Related]
4. Binding of the JmjC demethylase JARID1B to LSD1/NuRD suppresses angiogenesis and metastasis in breast cancer cells by repressing chemokine CCL14.
Li Q; Shi L; Gui B; Yu W; Wang J; Zhang D; Han X; Yao Z; Shang Y
Cancer Res; 2011 Nov; 71(21):6899-908. PubMed ID: 21937684
[TBL] [Abstract][Full Text] [Related]
5. Characterization of a Linked Jumonji Domain of the KDM5/JARID1 Family of Histone H3 Lysine 4 Demethylases.
Horton JR; Engstrom A; Zoeller EL; Liu X; Shanks JR; Zhang X; Johns MA; Vertino PM; Fu H; Cheng X
J Biol Chem; 2016 Feb; 291(6):2631-46. PubMed ID: 26645689
[TBL] [Abstract][Full Text] [Related]
6. Structure of the Arabidopsis JMJ14-H3K4me3 Complex Provides Insight into the Substrate Specificity of KDM5 Subfamily Histone Demethylases.
Yang Z; Qiu Q; Chen W; Jia B; Chen X; Hu H; He K; Deng X; Li S; Tao WA; Cao X; Du J
Plant Cell; 2018 Jan; 30(1):167-177. PubMed ID: 29233856
[TBL] [Abstract][Full Text] [Related]
7. The histone-H3K4-specific demethylase KDM5B binds to its substrate and product through distinct PHD fingers.
Klein BJ; Piao L; Xi Y; Rincon-Arano H; Rothbart SB; Peng D; Wen H; Larson C; Zhang X; Zheng X; Cortazar MA; Peña PV; Mangan A; Bentley DL; Strahl BD; Groudine M; Li W; Shi X; Kutateladze TG
Cell Rep; 2014 Jan; 6(2):325-35. PubMed ID: 24412361
[TBL] [Abstract][Full Text] [Related]
8. Identification of small molecule inhibitors of Jumonji AT-rich interactive domain 1B (JARID1B) histone demethylase by a sensitive high throughput screen.
Sayegh J; Cao J; Zou MR; Morales A; Blair LP; Norcia M; Hoyer D; Tackett AJ; Merkel JS; Yan Q
J Biol Chem; 2013 Mar; 288(13):9408-17. PubMed ID: 23408432
[TBL] [Abstract][Full Text] [Related]
9. The KDM5 family of histone demethylases as targets in oncology drug discovery.
Rasmussen PB; Staller P
Epigenomics; 2014 Jun; 6(3):277-86. PubMed ID: 25111482
[TBL] [Abstract][Full Text] [Related]
10. The PHD1 finger of KDM5B recognizes unmodified H3K4 during the demethylation of histone H3K4me2/3 by KDM5B.
Zhang Y; Yang H; Guo X; Rong N; Song Y; Xu Y; Lan W; Zhang X; Liu M; Xu Y; Cao C
Protein Cell; 2014 Nov; 5(11):837-50. PubMed ID: 24952722
[TBL] [Abstract][Full Text] [Related]
11. Histone demethylase lysine demethylase 5B in development and cancer.
Han M; Xu W; Cheng P; Jin H; Wang X
Oncotarget; 2017 Jan; 8(5):8980-8991. PubMed ID: 27974677
[TBL] [Abstract][Full Text] [Related]
12. The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36.
Klose RJ; Yamane K; Bae Y; Zhang D; Erdjument-Bromage H; Tempst P; Wong J; Zhang Y
Nature; 2006 Jul; 442(7100):312-6. PubMed ID: 16732292
[TBL] [Abstract][Full Text] [Related]
13. KDM5B demethylates H3K4 to recruit XRCC1 and promote chemoresistance.
Xu W; Zhou B; Zhao X; Zhu L; Xu J; Jiang Z; Chen D; Wei Q; Han M; Feng L; Wang S; Wang X; Zhou J; Jin H
Int J Biol Sci; 2018; 14(9):1122-1132. PubMed ID: 29989047
[TBL] [Abstract][Full Text] [Related]
14. KDM5B is a master regulator of the H3K4-methylome in stem cells, development and cancer.
Xhabija B; Kidder BL
Semin Cancer Biol; 2019 Aug; 57():79-85. PubMed ID: 30448242
[TBL] [Abstract][Full Text] [Related]
15. Enzyme kinetic studies of histone demethylases KDM4C and KDM6A: towards understanding selectivity of inhibitors targeting oncogenic histone demethylases.
Kristensen JB; Nielsen AL; Jørgensen L; Kristensen LH; Helgstrand C; Juknaite L; Kristensen JL; Kastrup JS; Clausen RP; Olsen L; Gajhede M
FEBS Lett; 2011 Jun; 585(12):1951-6. PubMed ID: 21575637
[TBL] [Abstract][Full Text] [Related]
16. Overexpressed KDM5B is associated with the progression of glioma and promotes glioma cell growth via downregulating p21.
Dai B; Hu Z; Huang H; Zhu G; Xiao Z; Wan W; Zhang P; Jia W; Zhang L
Biochem Biophys Res Commun; 2014 Nov; 454(1):221-7. PubMed ID: 25450384
[TBL] [Abstract][Full Text] [Related]
17. Identification of non-histone substrates for JMJD2A-C histone demethylases.
Ponnaluri VK; Vavilala DT; Putty S; Gutheil WG; Mukherji M
Biochem Biophys Res Commun; 2009 Dec; 390(2):280-4. PubMed ID: 19799855
[TBL] [Abstract][Full Text] [Related]
18. Inhibition of the histone demethylase, KDM5B, directly induces re-expression of tumor suppressor protein HEXIM1 in cancer cells.
Montano MM; Yeh IJ; Chen Y; Hernandez C; Kiselar JG; de la Fuente M; Lawes AM; Nieman MT; Kiser PD; Jacobberger J; Exner AA; Lawes MC
Breast Cancer Res; 2019 Dec; 21(1):138. PubMed ID: 31805991
[TBL] [Abstract][Full Text] [Related]
19. Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase.
Couture JF; Collazo E; Ortiz-Tello PA; Brunzelle JS; Trievel RC
Nat Struct Mol Biol; 2007 Aug; 14(8):689-95. PubMed ID: 17589523
[TBL] [Abstract][Full Text] [Related]
20. Lysine demethylase 5B (KDM5B): A potential anti-cancer drug target.
Zheng YC; Chang J; Wang LC; Ren HM; Pang JR; Liu HM
Eur J Med Chem; 2019 Jan; 161():131-140. PubMed ID: 30343192
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
