BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

310 related articles for article (PubMed ID: 22421967)

  • 1. Excitotoxic stimulus stabilizes PFKFB3 causing pentose-phosphate pathway to glycolysis switch and neurodegeneration.
    Rodriguez-Rodriguez P; Fernandez E; Almeida A; Bolaños JP
    Cell Death Differ; 2012 Oct; 19(10):1582-9. PubMed ID: 22421967
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C-Cdh1.
    Herrero-Mendez A; Almeida A; Fernández E; Maestre C; Moncada S; Bolaños JP
    Nat Cell Biol; 2009 Jun; 11(6):747-52. PubMed ID: 19448625
    [TBL] [Abstract][Full Text] [Related]  

  • 3. APC-Cdh1 Regulates Neuronal Apoptosis Through Modulating Glycolysis and Pentose-Phosphate Pathway After Oxygen-Glucose Deprivation and Reperfusion.
    Li Z; Zhang B; Yao W; Zhang C; Wan L; Zhang Y
    Cell Mol Neurobiol; 2019 Jan; 39(1):123-135. PubMed ID: 30460429
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeting PFKFB3 alleviates cerebral ischemia-reperfusion injury in mice.
    Burmistrova O; Olias-Arjona A; Lapresa R; Jimenez-Blasco D; Eremeeva T; Shishov D; Romanov S; Zakurdaeva K; Almeida A; Fedichev PO; Bolaños JP
    Sci Rep; 2019 Aug; 9(1):11670. PubMed ID: 31406177
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Glycolysis: a bioenergetic or a survival pathway?
    Bolaños JP; Almeida A; Moncada S
    Trends Biochem Sci; 2010 Mar; 35(3):145-9. PubMed ID: 20006513
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Brain energy metabolism in glutamate-receptor activation and excitotoxicity: role for APC/C-Cdh1 in the balance glycolysis/pentose phosphate pathway.
    Rodriguez-Rodriguez P; Almeida A; Bolaños JP
    Neurochem Int; 2013 Apr; 62(5):750-6. PubMed ID: 23416042
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Two ubiquitin ligases, APC/C-Cdh1 and SKP1-CUL1-F (SCF)-beta-TrCP, sequentially regulate glycolysis during the cell cycle.
    Tudzarova S; Colombo SL; Stoeber K; Carcamo S; Williams GH; Moncada S
    Proc Natl Acad Sci U S A; 2011 Mar; 108(13):5278-83. PubMed ID: 21402913
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PFKFB3-mediated glycolysis is involved in reactive astrocyte proliferation after oxygen-glucose deprivation/reperfusion and is regulated by Cdh1.
    Lv Y; Zhang B; Zhai C; Qiu J; Zhang Y; Yao W; Zhang C
    Neurochem Int; 2015 Dec; 91():26-33. PubMed ID: 26498254
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cdh1-Mediated Metabolic Switch from Pentose Phosphate Pathway to Glycolysis Contributes to Sevoflurane-Induced Neuronal Apoptosis in Developing Brain.
    Liu B; Bai W; Ou G; Zhang J
    ACS Chem Neurosci; 2019 May; 10(5):2332-2344. PubMed ID: 30741526
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular basis for the differential use of glucose and glutamine in cell proliferation as revealed by synchronized HeLa cells.
    Colombo SL; Palacios-Callender M; Frakich N; Carcamo S; Kovacs I; Tudzarova S; Moncada S
    Proc Natl Acad Sci U S A; 2011 Dec; 108(52):21069-74. PubMed ID: 22106309
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Anaphase-promoting complex/cyclosome-Cdh1 coordinates glycolysis and glutaminolysis with transition to S phase in human T lymphocytes.
    Colombo SL; Palacios-Callender M; Frakich N; De Leon J; Schmitt CA; Boorn L; Davis N; Moncada S
    Proc Natl Acad Sci U S A; 2010 Nov; 107(44):18868-73. PubMed ID: 20921411
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The pentose-phosphate pathway in neuronal survival against nitrosative stress.
    Bolaños JP; Almeida A
    IUBMB Life; 2010 Jan; 62(1):14-8. PubMed ID: 19937972
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 6-Phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 and 4: A pair of valves for fine-tuning of glucose metabolism in human cancer.
    Yi M; Ban Y; Tan Y; Xiong W; Li G; Xiang B
    Mol Metab; 2019 Feb; 20():1-13. PubMed ID: 30553771
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Increased 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 activity in response to EGFR signaling contributes to non-small cell lung cancer cell survival.
    Lypova N; Telang S; Chesney J; Imbert-Fernandez Y
    J Biol Chem; 2019 Jul; 294(27):10530-10543. PubMed ID: 31126985
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Increased concentrations of fructose 2,6-bisphosphate contribute to the Warburg effect in phosphatase and tensin homolog (PTEN)-deficient cells.
    Cordero-Espinoza L; Hagen T
    J Biol Chem; 2013 Dec; 288(50):36020-8. PubMed ID: 24169697
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PFKFB3 regulates oxidative stress homeostasis via its S-glutathionylation in cancer.
    Seo M; Lee YH
    J Mol Biol; 2014 Feb; 426(4):830-42. PubMed ID: 24295899
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase Suppresses Neuronal Apoptosis by Increasing Glycolysis and "cyclin-dependent kinase 1-Mediated Phosphorylation of p27 After Traumatic Spinal Cord Injury in Rats.
    Gao L; Wang C; Qin B; Li T; Xu W; Lenahan C; Ying G; Li J; Zhao T; Zhu Y; Chen G
    Cell Transplant; 2020; 29():963689720950226. PubMed ID: 32841050
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Role of Akt/PKB and PFKFB isoenzymes in the control of glycolysis, cell proliferation and protein synthesis in mitogen-stimulated thymocytes.
    Houddane A; Bultot L; Novellasdemunt L; Johanns M; Gueuning MA; Vertommen D; Coulie PG; Bartrons R; Hue L; Rider MH
    Cell Signal; 2017 Jun; 34():23-37. PubMed ID: 28235572
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of 6-phosphofructo-2-kinase (PFKFB3) suppresses glucose metabolism and the growth of HER2+ breast cancer.
    O'Neal J; Clem A; Reynolds L; Dougherty S; Imbert-Fernandez Y; Telang S; Chesney J; Clem BF
    Breast Cancer Res Treat; 2016 Nov; 160(1):29-40. PubMed ID: 27613609
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 6-Phosphofructo-2-kinase (PFKFB3) promotes cell cycle progression and suppresses apoptosis via Cdk1-mediated phosphorylation of p27.
    Yalcin A; Clem BF; Imbert-Fernandez Y; Ozcan SC; Peker S; O'Neal J; Klarer AC; Clem AL; Telang S; Chesney J
    Cell Death Dis; 2014 Jul; 5(7):e1337. PubMed ID: 25032860
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.