85 related articles for article (PubMed ID: 22425524)
1. Cytotoxic activity to acute myeloid leukemia cells by Antp-TPR hybrid peptide targeting Hsp90.
Horibe T; Kawamoto M; Kohno M; Kawakami K
J Biosci Bioeng; 2012 Jul; 114(1):96-103. PubMed ID: 22425524
[TBL] [Abstract][Full Text] [Related]
2. Designed hybrid TPR peptide targeting Hsp90 as a novel anticancer agent.
Horibe T; Kohno M; Haramoto M; Ohara K; Kawakami K
J Transl Med; 2011 Jan; 9():8. PubMed ID: 21235734
[TBL] [Abstract][Full Text] [Related]
3. Molecular mechanism of cytotoxicity induced by Hsp90-targeted Antp-TPR hybrid peptide in glioblastoma cells.
Horibe T; Torisawa A; Kohno M; Kawakami K
Mol Cancer; 2012 Aug; 11():59. PubMed ID: 22913813
[TBL] [Abstract][Full Text] [Related]
4. Synergetic cytotoxic activity toward breast cancer cells enhanced by the combination of Antp-TPR hybrid peptide targeting Hsp90 and Hsp70-targeted peptide.
Horibe T; Torisawa A; Kohno M; Kawakami K
BMC Cancer; 2014 Aug; 14():615. PubMed ID: 25159299
[TBL] [Abstract][Full Text] [Related]
5. Antileukemic activity of shepherdin and molecular diversity of hsp90 inhibitors.
Gyurkocza B; Plescia J; Raskett CM; Garlick DS; Lowry PA; Carter BZ; Andreeff M; Meli M; Colombo G; Altieri DC
J Natl Cancer Inst; 2006 Aug; 98(15):1068-77. PubMed ID: 16882944
[TBL] [Abstract][Full Text] [Related]
6. Mebendazole exhibits potent anti-leukemia activity on acute myeloid leukemia.
He L; Shi L; Du Z; Huang H; Gong R; Ma L; Chen L; Gao S; Lyu J; Gu H
Exp Cell Res; 2018 Aug; 369(1):61-68. PubMed ID: 29750898
[TBL] [Abstract][Full Text] [Related]
7. Abrogation of heat shock protein 70 induction as a strategy to increase antileukemia activity of heat shock protein 90 inhibitor 17-allylamino-demethoxy geldanamycin.
Guo F; Rocha K; Bali P; Pranpat M; Fiskus W; Boyapalle S; Kumaraswamy S; Balasis M; Greedy B; Armitage ES; Lawrence N; Bhalla K
Cancer Res; 2005 Nov; 65(22):10536-44. PubMed ID: 16288046
[TBL] [Abstract][Full Text] [Related]
8. A compound that inhibits the HOP-Hsp90 complex formation and has unique killing effects in breast cancer cell lines.
Pimienta G; Herbert KM; Regan L
Mol Pharm; 2011 Dec; 8(6):2252-61. PubMed ID: 21882818
[TBL] [Abstract][Full Text] [Related]
9. Gö6976, a FLT3 kinase inhibitor, exerts potent cytotoxic activity against acute leukemia via inhibition of survivin and MCL-1.
Yoshida A; Ookura M; Zokumasu K; Ueda T
Biochem Pharmacol; 2014 Jul; 90(1):16-24. PubMed ID: 24735609
[TBL] [Abstract][Full Text] [Related]
10. BJ-B11, a novel Hsp90 inhibitor, induces apoptosis in human chronic myeloid leukemia K562 cells through the mitochondria-dependent pathway.
Ju HQ; Wang SX; Xiang YF; Liu Z; Liu JY; Chen ZP; Zeng FL; Xia M; Liu ZH; Xing GW; Wang SY; Wang YF
Eur J Pharmacol; 2011 Sep; 666(1-3):26-34. PubMed ID: 21620825
[TBL] [Abstract][Full Text] [Related]
11. Specific Binding of Tetratricopeptide Repeat Proteins to Heat Shock Protein 70 (Hsp70) and Heat Shock Protein 90 (Hsp90) Is Regulated by Affinity and Phosphorylation.
Assimon VA; Southworth DR; Gestwicki JE
Biochemistry; 2015 Dec; 54(48):7120-31. PubMed ID: 26565746
[TBL] [Abstract][Full Text] [Related]
12. The Hsp90 inhibitor 17-allylamide-17-demethoxygeldanamycin induces apoptosis and differentiation of Kasumi-1 harboring the Asn822Lys KIT mutation and down-regulates KIT protein level.
Yu W; Rao Q; Wang M; Tian Z; Lin D; Liu X; Wang J
Leuk Res; 2006 May; 30(5):575-82. PubMed ID: 16213582
[TBL] [Abstract][Full Text] [Related]
13. Cytotoxic effects of high concentrations of sodium ascorbate on human myeloid cell lines.
Mastrangelo D; Massai L; Lo Coco F; Noguera NI; Borgia L; Fioritoni G; Berardi A; Iacone A; Muscettola M; Pelosi E; Castelli G; Testa U; Di Pisa F; Grasso G
Ann Hematol; 2015 Nov; 94(11):1807-16. PubMed ID: 26264692
[TBL] [Abstract][Full Text] [Related]
14. siRNA-mediated inhibition of survivin gene enhances the anti-cancer effect of etoposide in U-937 acute myeloid leukemia cells.
Jafarlou M; Baradaran B; Shanehbandi D; Saedi TA; Jafarlou V; Ismail P; Othman F
Cell Mol Biol (Noisy-le-grand); 2016 May; 62(6):44-9. PubMed ID: 27262801
[TBL] [Abstract][Full Text] [Related]
15. A novel cyano derivative of 11-keto-β-boswellic acid causes apoptotic death by disrupting PI3K/AKT/Hsp-90 cascade, mitochondrial integrity, and other cell survival signaling events in HL-60 cells.
Khan S; Kaur R; Shah BA; Malik F; Kumar A; Bhushan S; Jain SK; Taneja SC; Singh J
Mol Carcinog; 2012 Sep; 51(9):679-95. PubMed ID: 21751262
[TBL] [Abstract][Full Text] [Related]
16. Heat shock protein 90 inhibition is cytotoxic to primary AML cells expressing mutant FLT3 and results in altered downstream signalling.
Al Shaer L; Walsby E; Gilkes A; Tonks A; Walsh V; Mills K; Burnett A; Rowntree C
Br J Haematol; 2008 May; 141(4):483-93. PubMed ID: 18373709
[TBL] [Abstract][Full Text] [Related]
17. Ganetespib, a unique triazolone-containing Hsp90 inhibitor, exhibits potent antitumor activity and a superior safety profile for cancer therapy.
Ying W; Du Z; Sun L; Foley KP; Proia DA; Blackman RK; Zhou D; Inoue T; Tatsuta N; Sang J; Ye S; Acquaviva J; Ogawa LS; Wada Y; Barsoum J; Koya K
Mol Cancer Ther; 2012 Feb; 11(2):475-84. PubMed ID: 22144665
[TBL] [Abstract][Full Text] [Related]
18. Non-benzoquinone geldanamycin analogs trigger various forms of death in human breast cancer cells.
Zhang Z; Li HM; Zhou C; Li Q; Ma L; Zhang Z; Sun Y; Wang L; Zhang X; Zhu B; Hong YS; Wu CZ; Liu H
J Exp Clin Cancer Res; 2016 Sep; 35(1):149. PubMed ID: 27658586
[TBL] [Abstract][Full Text] [Related]
19. Targeting the Hsp90 C-terminal domain by the chemically accessible dihydropyrimidinone scaffold.
Strocchia M; Terracciano S; Chini MG; Vassallo A; Vaccaro MC; Dal Piaz F; Leone A; Riccio R; Bruno I; Bifulco G
Chem Commun (Camb); 2015 Mar; 51(18):3850-3. PubMed ID: 25656927
[TBL] [Abstract][Full Text] [Related]
20. Concurrent targeting Akt and sphingosine kinase 1 by A-674563 in acute myeloid leukemia cells.
Xu L; Zhang Y; Gao M; Wang G; Fu Y
Biochem Biophys Res Commun; 2016 Apr; 472(4):662-8. PubMed ID: 26920060
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]