BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

162 related articles for article (PubMed ID: 22430364)

  • 1. Assessment and modulation of forsythiaside absorption with MDCKII cells and validation with in situ intestinal experiment.
    Li YX; Zhang RQ; Peng C
    Eur J Drug Metab Pharmacokinet; 2012 Sep; 37(3):179-86. PubMed ID: 22430364
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Both P-gp and MRP2 mediate transport of Lopinavir, a protease inhibitor.
    Agarwal S; Pal D; Mitra AK
    Int J Pharm; 2007 Jul; 339(1-2):139-47. PubMed ID: 17451894
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The role of efflux transporters on the transport of highly toxic aconitine, mesaconitine, hypaconitine, and their hydrolysates, as determined in cultured Caco-2 and transfected MDCKII cells.
    Ye L; Yang X; Yang Z; Gao S; Yin T; Liu W; Wang F; Hu M; Liu Z
    Toxicol Lett; 2013 Feb; 216(2-3):86-99. PubMed ID: 23200901
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Evaluation of intestinal absorption of amtolmetin guacyl in rats: breast cancer resistant protein as a primary barrier of oral bioavailability.
    Rong Z; Xu Y; Zhang C; Xiang D; Li X; Liu D
    Life Sci; 2013 Feb; 92(3):245-51. PubMed ID: 23333829
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Direct evidence that saquinavir is transported by multidrug resistance-associated protein (MRP1) and canalicular multispecific organic anion transporter (MRP2).
    Williams GC; Liu A; Knipp G; Sinko PJ
    Antimicrob Agents Chemother; 2002 Nov; 46(11):3456-62. PubMed ID: 12384350
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Role of P-glycoprotein in the intestinal absorption of tanshinone IIA, a major active ingredient in the root of Salvia miltiorrhiza Bunge.
    Yu XY; Lin SG; Zhou ZW; Chen X; Liang J; Liu PQ; Duan W; Chowbay B; Wen JY; Li CG; Zhou SF
    Curr Drug Metab; 2007 May; 8(4):325-40. PubMed ID: 17504222
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effect of the ATP-binding cassette drug transporters ABCB1, ABCG2, and ABCC2 on erlotinib hydrochloride (Tarceva) disposition in in vitro and in vivo pharmacokinetic studies employing Bcrp1-/-/Mdr1a/1b-/- (triple-knockout) and wild-type mice.
    Marchetti S; de Vries NA; Buckle T; Bolijn MJ; van Eijndhoven MA; Beijnen JH; Mazzanti R; van Tellingen O; Schellens JH
    Mol Cancer Ther; 2008 Aug; 7(8):2280-7. PubMed ID: 18723475
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Small intestinal efflux mediated by MRP2 and BCRP shifts sulfasalazine intestinal permeability from high to low, enabling its colonic targeting.
    Dahan A; Amidon GL
    Am J Physiol Gastrointest Liver Physiol; 2009 Aug; 297(2):G371-7. PubMed ID: 19541926
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Interaction of gatifloxacin with efflux transporters: a possible mechanism for drug resistance.
    Kwatra D; Vadlapatla RK; Vadlapudi AD; Pal D; Mitra AK
    Int J Pharm; 2010 Aug; 395(1-2):114-21. PubMed ID: 20573570
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Characterization and Validation of Canine P-Glycoprotein-Deficient MDCK II Cell Lines for Efflux Substrate Screening.
    Ye D; Harder A; Fang Z; Weinheimer M; Laplanche L; Mezler M
    Pharm Res; 2020 Sep; 37(10):194. PubMed ID: 32918191
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Breast Cancer Resistance Protein and Multidrug Resistance Protein 2 Determine the Disposition of Esculetin-7-O-Glucuronide and 4-Methylesculetin-7-O-Glucuronide.
    Li Y; Song W; Ou X; Luo G; Xie Y; Sun R; Wang Y; Qi X; Hu M; Liu Z; Zhu L
    Drug Metab Dispos; 2019 Mar; 47(3):203-214. PubMed ID: 30602435
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Breast cancer resistance protein (Bcrp1/Abcg2) limits net intestinal uptake of quercetin in rats by facilitating apical efflux of glucuronides.
    Sesink AL; Arts IC; de Boer VC; Breedveld P; Schellens JH; Hollman PC; Russel FG
    Mol Pharmacol; 2005 Jun; 67(6):1999-2006. PubMed ID: 15749994
    [TBL] [Abstract][Full Text] [Related]  

  • 13. In vitro transport of gimatecan (7-t-butoxyiminomethylcamptothecin) by breast cancer resistance protein, P-glycoprotein, and multidrug resistance protein 2.
    Marchetti S; Oostendorp RL; Pluim D; van Eijndhoven M; van Tellingen O; Schinkel AH; Versace R; Beijnen JH; Mazzanti R; Schellens JH
    Mol Cancer Ther; 2007 Dec; 6(12 Pt 1):3307-13. PubMed ID: 18089724
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Intestinal ciprofloxacin efflux: the role of breast cancer resistance protein (ABCG2).
    Haslam IS; Wright JA; O'Reilly DA; Sherlock DJ; Coleman T; Simmons NL
    Drug Metab Dispos; 2011 Dec; 39(12):2321-8. PubMed ID: 21930826
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of novel specific and general inhibitors of the three major human ATP-binding cassette transporters P-gp, BCRP and MRP2 among registered drugs.
    Matsson P; Pedersen JM; Norinder U; Bergström CA; Artursson P
    Pharm Res; 2009 Aug; 26(8):1816-31. PubMed ID: 19421845
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterization of efflux transport of the PDE5 inhibitors, vardenafil and sildenafil.
    Choi MK; Song IS
    J Pharm Pharmacol; 2012 Aug; 64(8):1074-83. PubMed ID: 22775210
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Involvement of P-glycoprotein, multidrug resistance protein 2 and breast cancer resistance protein in the transport of belotecan and topotecan in Caco-2 and MDCKII cells.
    Li H; Jin HE; Kim W; Han YH; Kim DD; Chung SJ; Shim CK
    Pharm Res; 2008 Nov; 25(11):2601-12. PubMed ID: 18654741
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
    Lin X; Skolnik S; Chen X; Wang J
    Drug Metab Dispos; 2011 Feb; 39(2):265-74. PubMed ID: 21051535
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Multiple efflux pumps are involved in the transepithelial transport of colchicine: combined effect of p-glycoprotein and multidrug resistance-associated protein 2 leads to decreased intestinal absorption throughout the entire small intestine.
    Dahan A; Sabit H; Amidon GL
    Drug Metab Dispos; 2009 Oct; 37(10):2028-36. PubMed ID: 19589874
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Membrane transport of camptothecin: facilitation by human P-glycoprotein (ABCB1) and multidrug resistance protein 2 (ABCC2).
    Lalloo AK; Luo FR; Guo A; Paranjpe PV; Lee SH; Vyas V; Rubin E; Sinko PJ
    BMC Med; 2004 May; 2():16. PubMed ID: 15125776
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.