577 related articles for article (PubMed ID: 22439938)
1. Transient low doses of DNA-demethylating agents exert durable antitumor effects on hematological and epithelial tumor cells.
Tsai HC; Li H; Van Neste L; Cai Y; Robert C; Rassool FV; Shin JJ; Harbom KM; Beaty R; Pappou E; Harris J; Yen RW; Ahuja N; Brock MV; Stearns V; Feller-Kopman D; Yarmus LB; Lin YC; Welm AL; Issa JP; Minn I; Matsui W; Jang YY; Sharkis SJ; Baylin SB; Zahnow CA
Cancer Cell; 2012 Mar; 21(3):430-46. PubMed ID: 22439938
[TBL] [Abstract][Full Text] [Related]
2. Pharmacologic reversion of epigenetic silencing of the PRKD1 promoter blocks breast tumor cell invasion and metastasis.
Borges S; Döppler H; Perez EA; Andorfer CA; Sun Z; Anastasiadis PZ; Thompson E; Geiger XJ; Storz P
Breast Cancer Res; 2013 Aug; 15(2):R66. PubMed ID: 23971832
[TBL] [Abstract][Full Text] [Related]
3. Transformation-dependent silencing of tumor-selective apoptosis-inducing TRAIL by DNA hypermethylation is antagonized by decitabine.
Lund P; Kotova I; Kedinger V; Khanwalkar H; Voltz E; Hahn WC; Gronemeyer H
Mol Cancer Ther; 2011 Sep; 10(9):1611-23. PubMed ID: 21697397
[TBL] [Abstract][Full Text] [Related]
4. LINE-1 methylation in plasma DNA as a biomarker of activity of DNA methylation inhibitors in patients with solid tumors.
Aparicio A; North B; Barske L; Wang X; Bollati V; Weisenberger D; Yoo C; Tannir N; Horne E; Groshen S; Jones P; Yang A; Issa JP
Epigenetics; 2009 Apr; 4(3):176-84. PubMed ID: 19421002
[TBL] [Abstract][Full Text] [Related]
5. Decitabine effect on tumor global DNA methylation and other parameters in a phase I trial in refractory solid tumors and lymphomas.
Stewart DJ; Issa JP; Kurzrock R; Nunez MI; Jelinek J; Hong D; Oki Y; Guo Z; Gupta S; Wistuba II
Clin Cancer Res; 2009 Jun; 15(11):3881-8. PubMed ID: 19470736
[TBL] [Abstract][Full Text] [Related]
6. DNA methylation and gene silencing in cancer.
Baylin SB
Nat Clin Pract Oncol; 2005 Dec; 2 Suppl 1():S4-11. PubMed ID: 16341240
[TBL] [Abstract][Full Text] [Related]
7. 5-azacytidine and decitabine exert proapoptotic effects on neoplastic mast cells: role of FAS-demethylation and FAS re-expression, and synergism with FAS-ligand.
Ghanim V; Herrmann H; Heller G; Peter B; Hadzijusufovic E; Blatt K; Schuch K; Cerny-Reiterer S; Mirkina I; Karlic H; Pickl WF; Zöchbauer-Müller S; Valent P
Blood; 2012 May; 119(18):4242-52. PubMed ID: 22438247
[TBL] [Abstract][Full Text] [Related]
8. Genome-wide methylation and expression profiling identifies promoter characteristics affecting demethylation-induced gene up-regulation in melanoma.
Rubinstein JC; Tran N; Ma S; Halaban R; Krauthammer M
BMC Med Genomics; 2010 Feb; 3():4. PubMed ID: 20144234
[TBL] [Abstract][Full Text] [Related]
9. Genomic screening for genes upregulated by demethylation revealed novel targets of epigenetic silencing in breast cancer.
Fujikane T; Nishikawa N; Toyota M; Suzuki H; Nojima M; Maruyama R; Ashida M; Ohe-Toyota M; Kai M; Nishidate T; Sasaki Y; Ohmura T; Hirata K; Tokino T
Breast Cancer Res Treat; 2010 Aug; 122(3):699-710. PubMed ID: 19859801
[TBL] [Abstract][Full Text] [Related]
10. Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in hematopoietic malignancies.
Issa JP; Garcia-Manero G; Giles FJ; Mannari R; Thomas D; Faderl S; Bayar E; Lyons J; Rosenfeld CS; Cortes J; Kantarjian HM
Blood; 2004 Mar; 103(5):1635-40. PubMed ID: 14604977
[TBL] [Abstract][Full Text] [Related]
11. Inhibition of dna methylation by 5-aza-2'-deoxycytidine correlates with induction of K562 cells differentiation.
Fabianowska-Majewska K; Wyczechowska D; Czyz M
Adv Exp Med Biol; 2000; 486():343-7. PubMed ID: 11783512
[No Abstract] [Full Text] [Related]
12. Hypermethylation of the p16 (Ink4a) promoter in B6C3F1 mouse primary lung adenocarcinomas and mouse lung cell lines.
Patel AC; Anna CH; Foley JF; Stockton PS; Tyson FL; Barrett JC; Devereux TR
Carcinogenesis; 2000 Sep; 21(9):1691-700. PubMed ID: 10964101
[TBL] [Abstract][Full Text] [Related]
13. Five-aza-2'-deoxycytidine-induced hypomethylation of cholesterol 25-hydroxylase gene is responsible for cell death of myelodysplasia/leukemia cells.
Tsujioka T; Yokoi A; Itano Y; Takahashi K; Ouchida M; Okamoto S; Kondo T; Suemori S; Tohyama Y; Tohyama K
Sci Rep; 2015 Nov; 5():16709. PubMed ID: 26577244
[TBL] [Abstract][Full Text] [Related]
14. Targeting the unique methylation pattern of androgen receptor (AR) promoter in prostate stem/progenitor cells with 5-aza-2'-deoxycytidine (5-AZA) leads to suppressed prostate tumorigenesis.
Tian J; Lee SO; Liang L; Luo J; Huang CK; Li L; Niu Y; Chang C
J Biol Chem; 2012 Nov; 287(47):39954-66. PubMed ID: 23012352
[TBL] [Abstract][Full Text] [Related]
15. The DNA methyltransferase inhibitors azacitidine, decitabine and zebularine exert differential effects on cancer gene expression in acute myeloid leukemia cells.
Flotho C; Claus R; Batz C; Schneider M; Sandrock I; Ihde S; Plass C; Niemeyer CM; Lübbert M
Leukemia; 2009 Jun; 23(6):1019-28. PubMed ID: 19194470
[TBL] [Abstract][Full Text] [Related]
16. Comparison of biological effects of non-nucleoside DNA methylation inhibitors versus 5-aza-2'-deoxycytidine.
Chuang JC; Yoo CB; Kwan JM; Li TW; Liang G; Yang AS; Jones PA
Mol Cancer Ther; 2005 Oct; 4(10):1515-20. PubMed ID: 16227400
[TBL] [Abstract][Full Text] [Related]
17. Decitabine activates specific caspases downstream of p73 in myeloid leukemia.
Tamm I; Wagner M; Schmelz K
Ann Hematol; 2005 Dec; 84 Suppl 1():47-53. PubMed ID: 16193303
[TBL] [Abstract][Full Text] [Related]
18. Decitabine has a biphasic effect on natural killer cell viability, phenotype, and function under proliferative conditions.
Kopp LM; Ray A; Denman CJ; Senyukov VS; Somanchi SS; Zhu S; Lee DA
Mol Immunol; 2013 Jul; 54(3-4):296-301. PubMed ID: 23328088
[TBL] [Abstract][Full Text] [Related]
19. Evaluation of a 7-day continuous intravenous infusion of decitabine: inhibition of promoter-specific and global genomic DNA methylation.
Samlowski WE; Leachman SA; Wade M; Cassidy P; Porter-Gill P; Busby L; Wheeler R; Boucher K; Fitzpatrick F; Jones DA; Karpf AR
J Clin Oncol; 2005 Jun; 23(17):3897-905. PubMed ID: 15753459
[TBL] [Abstract][Full Text] [Related]
20. Role of estrogen receptor gene demethylation and DNA methyltransferase.DNA adduct formation in 5-aza-2'deoxycytidine-induced cytotoxicity in human breast cancer cells.
Ferguson AT; Vertino PM; Spitzner JR; Baylin SB; Muller MT; Davidson NE
J Biol Chem; 1997 Dec; 272(51):32260-6. PubMed ID: 9405430
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
