328 related articles for article (PubMed ID: 22447512)
21. Inhibition of the SUV4-20 H1 histone methyltransferase increases frataxin expression in Friedreich's ataxia patient cells.
Vilema-Enríquez G; Quinlan R; Kilfeather P; Mazzone R; Saqlain S; Del Molino Del Barrio I; Donato A; Corda G; Li F; Vedadi M; Németh AH; Brennan PE; Wade-Martins R
J Biol Chem; 2020 Dec; 295(52):17973-17985. PubMed ID: 33028632
[TBL] [Abstract][Full Text] [Related]
22. PPAR-gamma agonist Azelaoyl PAF increases frataxin protein and mRNA expression: new implications for the Friedreich's ataxia therapy.
Marmolino D; Acquaviva F; Pinelli M; Monticelli A; Castaldo I; Filla A; Cocozza S
Cerebellum; 2009 Jun; 8(2):98-103. PubMed ID: 19104905
[TBL] [Abstract][Full Text] [Related]
23. Alleviating GAA Repeat Induced Transcriptional Silencing of the Friedreich's Ataxia Gene During Somatic Cell Reprogramming.
Polak U; Li Y; Butler JS; Napierala M
Stem Cells Dev; 2016 Dec; 25(23):1788-1800. PubMed ID: 27615158
[TBL] [Abstract][Full Text] [Related]
24. GIFT-1, a phase IIa clinical trial to test the safety and efficacy of IFNγ administration in FRDA patients.
Marcotulli C; Fortuni S; Arcuri G; Tomassini B; Leonardi L; Pierelli F; Testi R; Casali C
Neurol Sci; 2016 Mar; 37(3):361-4. PubMed ID: 26621361
[TBL] [Abstract][Full Text] [Related]
25. 'Mitochondrial energy imbalance and lipid peroxidation cause cell death in Friedreich's ataxia'.
Abeti R; Parkinson MH; Hargreaves IP; Angelova PR; Sandi C; Pook MA; Giunti P; Abramov AY
Cell Death Dis; 2016 May; 7(5):e2237. PubMed ID: 27228352
[TBL] [Abstract][Full Text] [Related]
26. Ferroptosis as a Novel Therapeutic Target for Friedreich's Ataxia.
Cotticelli MG; Xia S; Lin D; Lee T; Terrab L; Wipf P; Huryn DM; Wilson RB
J Pharmacol Exp Ther; 2019 Apr; 369(1):47-54. PubMed ID: 30635474
[TBL] [Abstract][Full Text] [Related]
27. Normal and Friedreich ataxia cells express different isoforms of frataxin with complementary roles in iron-sulfur cluster assembly.
Gakh O; Bedekovics T; Duncan SF; Smith DY; Berkholz DS; Isaya G
J Biol Chem; 2010 Dec; 285(49):38486-501. PubMed ID: 20889968
[TBL] [Abstract][Full Text] [Related]
28. MutLα heterodimers modify the molecular phenotype of Friedreich ataxia.
Ezzatizadeh V; Sandi C; Sandi M; Anjomani-Virmouni S; Al-Mahdawi S; Pook MA
PLoS One; 2014; 9(6):e100523. PubMed ID: 24971578
[TBL] [Abstract][Full Text] [Related]
29. Generation and characterization of iPSC lines from Friedreich's ataxia patient (FRDA) with GAA.TTC repeat expansion in the Frataxin (FXN) gene's first intron (IGIBi016-A) and a non-FRDA healthy control individual (IGIBi017-A).
Ahmad I; Kamai A; Zahra S; Kapoor H; Kumar Srivastava A; Faruq M
Stem Cell Res; 2024 Jun; 77():103382. PubMed ID: 38484450
[TBL] [Abstract][Full Text] [Related]
30. Friedreich's Ataxia: from the (GAA)n repeat mediated silencing to new promising molecules for therapy.
Marmolino D; Acquaviva F
Cerebellum; 2009 Sep; 8(3):245-59. PubMed ID: 19165552
[TBL] [Abstract][Full Text] [Related]
31. Frataxin-deficient neurons and mice models of Friedreich ataxia are improved by TAT-MTScs-FXN treatment.
Britti E; Delaspre F; Feldman A; Osborne M; Greif H; Tamarit J; Ros J
J Cell Mol Med; 2018 Feb; 22(2):834-848. PubMed ID: 28980774
[TBL] [Abstract][Full Text] [Related]
32. Friedreich ataxia: an update on animal models, frataxin function and therapies.
González-Cabo P; Llorens JV; Palau F; Moltó MD
Adv Exp Med Biol; 2009; 652():247-61. PubMed ID: 20225031
[TBL] [Abstract][Full Text] [Related]
33. Neurodegeneration in Friedreich's ataxia: from defective frataxin to oxidative stress.
Gomes CM; Santos R
Oxid Med Cell Longev; 2013; 2013():487534. PubMed ID: 23936609
[TBL] [Abstract][Full Text] [Related]
34. The Regulation of the Disease-Causing Gene
Dong YN; Mercado-Ayón E; Coulman J; Flatley L; Ngaba LV; Adeshina MW; Lynch DR
Cells; 2024 Jun; 13(12):. PubMed ID: 38920668
[TBL] [Abstract][Full Text] [Related]
35. Frataxin deficiency alters gene expression in Friedreich ataxia derived IPSC-neurons and cardiomyocytes.
Angulo MB; Bertalovitz A; Argenziano MA; Yang J; Patel A; Zesiewicz T; McDonald TV
Mol Genet Genomic Med; 2023 Jan; 11(1):e2093. PubMed ID: 36369844
[TBL] [Abstract][Full Text] [Related]
36. Induced pluripotent stem cells from friedreich ataxia patients fail to upregulate frataxin during in vitro differentiation to peripheral sensory neurons.
Eigentler A; Boesch S; Schneider R; Dechant G; Nat R
Stem Cells Dev; 2013 Dec; 22(24):3271-82. PubMed ID: 23879205
[TBL] [Abstract][Full Text] [Related]
37. Beyond loss of frataxin: the complex molecular pathology of Friedreich ataxia.
Evans-Galea MV; Lockhart PJ; Galea CA; Hannan AJ; Delatycki MB
Discov Med; 2014 Jan; 17(91):25-35. PubMed ID: 24411698
[TBL] [Abstract][Full Text] [Related]
38. DNA methylation in Friedreich ataxia silences expression of frataxin isoform E.
Rodden LN; Gilliam KM; Lam C; Rojsajjakul T; Mesaros C; Dionisi C; Pook M; Pandolfo M; Lynch DR; Blair IA; Bidichandani SI
Sci Rep; 2022 Mar; 12(1):5031. PubMed ID: 35322126
[TBL] [Abstract][Full Text] [Related]
39. Transplantation of wild-type mouse hematopoietic stem and progenitor cells ameliorates deficits in a mouse model of Friedreich's ataxia.
Rocca CJ; Goodman SM; Dulin JN; Haquang JH; Gertsman I; Blondelle J; Smith JLM; Heyser CJ; Cherqui S
Sci Transl Med; 2017 Oct; 9(413):. PubMed ID: 29070698
[TBL] [Abstract][Full Text] [Related]
40. DNA repair pathways are altered in neural cell models of frataxin deficiency.
Moreno-Lorite J; Pérez-Luz S; Katsu-Jiménez Y; Oberdoerfer D; Díaz-Nido J
Mol Cell Neurosci; 2021 Mar; 111():103587. PubMed ID: 33418083
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
