237 related articles for article (PubMed ID: 22449202)
1. Cationic amphiphilic drugs cause a marked expansion of apparent lysosomal volume: implications for an intracellular distribution-based drug interaction.
Funk RS; Krise JP
Mol Pharm; 2012 May; 9(5):1384-95. PubMed ID: 22449202
[TBL] [Abstract][Full Text] [Related]
2. Evaluating the roles of autophagy and lysosomal trafficking defects in intracellular distribution-based drug-drug interactions involving lysosomes.
Logan R; Kong A; Krise JP
J Pharm Sci; 2013 Nov; 102(11):4173-80. PubMed ID: 23970383
[TBL] [Abstract][Full Text] [Related]
3. Lysosomal sequestration (trapping) of lipophilic amine (cationic amphiphilic) drugs in immortalized human hepatocytes (Fa2N-4 cells).
Kazmi F; Hensley T; Pope C; Funk RS; Loewen GJ; Buckley DB; Parkinson A
Drug Metab Dispos; 2013 Apr; 41(4):897-905. PubMed ID: 23378628
[TBL] [Abstract][Full Text] [Related]
4. Time-dependent effects of hydrophobic amine-containing drugs on lysosome structure and biogenesis in cultured human fibroblasts.
Logan R; Kong AC; Krise JP
J Pharm Sci; 2014 Oct; 103(10):3287-96. PubMed ID: 25042198
[TBL] [Abstract][Full Text] [Related]
5. Drug-drug interactions involving lysosomes: mechanisms and potential clinical implications.
Logan R; Funk RS; Axcell E; Krise JP
Expert Opin Drug Metab Toxicol; 2012 Aug; 8(8):943-58. PubMed ID: 22616667
[TBL] [Abstract][Full Text] [Related]
6. Amine-containing molecules and the induction of an expanded lysosomal volume phenotype: a structure-activity relationship study.
Logan R; Kong AC; Axcell E; Krise JP
J Pharm Sci; 2014 May; 103(5):1572-80. PubMed ID: 24647827
[TBL] [Abstract][Full Text] [Related]
7. Lysosomal trapping as an important mechanism involved in the cellular distribution of perazine and in pharmacokinetic interaction with antidepressants.
Daniel WA; Wójcikowski J
Eur Neuropsychopharmacol; 1999 Dec; 9(6):483-91. PubMed ID: 10625116
[TBL] [Abstract][Full Text] [Related]
8. In Vitro and in Silico Tools To Assess Extent of Cellular Uptake and Lysosomal Sequestration of Respiratory Drugs in Human Alveolar Macrophages.
Ufuk A; Assmus F; Francis L; Plumb J; Damian V; Gertz M; Houston JB; Galetin A
Mol Pharm; 2017 Apr; 14(4):1033-1046. PubMed ID: 28252969
[TBL] [Abstract][Full Text] [Related]
9. Hydroxypropyl-beta and -gamma cyclodextrins rescue cholesterol accumulation in Niemann-Pick C1 mutant cell via lysosome-associated membrane protein 1.
Singhal A; Szente L; Hildreth JEK; Song B
Cell Death Dis; 2018 Oct; 9(10):1019. PubMed ID: 30282967
[TBL] [Abstract][Full Text] [Related]
10. Interactions between promazine and antidepressants at the level of cellular distribution.
Daniel WA; Wójcikowski J
Pharmacol Toxicol; 1997 Dec; 81(6):259-64. PubMed ID: 9444666
[TBL] [Abstract][Full Text] [Related]
11. Induced Pluripotent Stem Cells for Disease Modeling and Evaluation of Therapeutics for Niemann-Pick Disease Type A.
Long Y; Xu M; Li R; Dai S; Beers J; Chen G; Soheilian F; Baxa U; Wang M; Marugan JJ; Muro S; Li Z; Brady R; Zheng W
Stem Cells Transl Med; 2016 Dec; 5(12):1644-1655. PubMed ID: 27484861
[TBL] [Abstract][Full Text] [Related]
12. Poly-β-cyclodextrin Supramolecular Nanoassembly with a pH-Sensitive Switch Removing Lysosomal Cholesterol Crystals for Antiatherosclerosis.
Zhang Y; Gong F; Wu Y; Hou S; Xue L; Su Z; Zhang C
Nano Lett; 2021 Nov; 21(22):9736-9745. PubMed ID: 34748340
[TBL] [Abstract][Full Text] [Related]
13. The role of lysosomes in limiting drug toxicity in mice.
Ndolo RA; Forrest ML; Krise JP
J Pharmacol Exp Ther; 2010 Apr; 333(1):120-8. PubMed ID: 20056778
[TBL] [Abstract][Full Text] [Related]
14. Lysosomal adaptation: How cells respond to lysosomotropic compounds.
Lu S; Sung T; Lin N; Abraham RT; Jessen BA
PLoS One; 2017; 12(3):e0173771. PubMed ID: 28301521
[TBL] [Abstract][Full Text] [Related]
15. In vitro evaluation of 2-hydroxyalkylated β-cyclodextrins as potential therapeutic agents for Niemann-Pick Type C disease.
Kondo Y; Tokumaru H; Ishitsuka Y; Matsumoto T; Taguchi M; Motoyama K; Higashi T; Arima H; Matsuo M; Higaki K; Ohno K; Irie T
Mol Genet Metab; 2016 Jul; 118(3):214-219. PubMed ID: 27184436
[TBL] [Abstract][Full Text] [Related]
16. Quantitation of Lysosomal Trapping of Basic Lipophilic Compounds Using In Vitro Assays and In Silico Predictions Based on the Determination of the Full pH Profile of the Endo-/Lysosomal System in Rat Hepatocytes.
Schmitt MV; Lienau P; Fricker G; Reichel A
Drug Metab Dispos; 2019 Jan; 47(1):49-57. PubMed ID: 30409837
[TBL] [Abstract][Full Text] [Related]
17. Intracellular trafficking of cholesterol monitored with a cyclodextrin.
Neufeld EB; Cooney AM; Pitha J; Dawidowicz EA; Dwyer NK; Pentchev PG; Blanchette-Mackie EJ
J Biol Chem; 1996 Aug; 271(35):21604-13. PubMed ID: 8702948
[TBL] [Abstract][Full Text] [Related]
18. Contribution of lysosomal trapping to the total tissue uptake of psychotropic drugs.
Daniel WA; Wójcikowski J
Pharmacol Toxicol; 1997 Feb; 80(2):62-8. PubMed ID: 9060036
[TBL] [Abstract][Full Text] [Related]
19. Differential Effects of 2-Hydroxypropyl-Cyclodextrins on Lipid Accumulation in
Hoque S; Kondo Y; Sakata N; Yamada Y; Fukaura M; Higashi T; Motoyama K; Arima H; Higaki K; Hayashi A; Komiya T; Ishitsuka Y; Irie T
Int J Mol Sci; 2020 Jan; 21(3):. PubMed ID: 32019132
[TBL] [Abstract][Full Text] [Related]
20. Uptake of imipramine in rat liver lysosomes in vitro and its inhibition by basic drugs.
Ishizaki J; Yokogawa K; Ichimura F; Ohkuma S
J Pharmacol Exp Ther; 2000 Sep; 294(3):1088-98. PubMed ID: 10945864
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]