BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

239 related articles for article (PubMed ID: 22449247)

  • 1. Vitamin D receptor ligands: the impact of crystal structures.
    Carlberg C; Molnár F; Mouriño A
    Expert Opin Ther Pat; 2012 Apr; 22(4):417-35. PubMed ID: 22449247
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Vitamin D receptor 2016: novel ligands and structural insights.
    Maestro MA; Molnár F; Mouriño A; Carlberg C
    Expert Opin Ther Pat; 2016 Nov; 26(11):1291-1306. PubMed ID: 27454349
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel 1alpha,25-dihydroxyvitamin D3 analogues with the side chain at C12.
    González-Avión XC; Mouriño A; Rochel N; Moras D
    J Med Chem; 2006 Mar; 49(5):1509-16. PubMed ID: 16509569
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Molecular basis of the selective activity of vitamin D analogues.
    Carlberg C
    J Cell Biochem; 2003 Feb; 88(2):274-81. PubMed ID: 12520526
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Natural metabolites of 1alpha,25-dihydroxyvitamin D(3) retain biologic activity mediated through the vitamin D receptor.
    Harant H; Spinner D; Reddy GS; Lindley IJ
    J Cell Biochem; 2000 Apr; 78(1):112-20. PubMed ID: 10797570
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural evaluation of the agonistic action of a vitamin D analog with two side chains binding to the nuclear vitamin D receptor.
    Väisänen S; Peräkylä M; Kärkkäinen JI; Uskokovic MR; Carlberg C
    Mol Pharmacol; 2003 Jun; 63(6):1230-7. PubMed ID: 12761332
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Critical role of helix 12 of the vitamin D(3) receptor for the partial agonism of carboxylic ester antagonists.
    Väisänen S; Peräkylä M; Kärkkäinen JI; Steinmeyer A; Carlberg C
    J Mol Biol; 2002 Jan; 315(2):229-38. PubMed ID: 11779241
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Therapeutic applications for novel non-hypercalcemic vitamin D receptor ligands.
    Choi M; Makishima M
    Expert Opin Ther Pat; 2009 May; 19(5):593-606. PubMed ID: 19441936
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Vitamin D receptor ligands for osteoporosis.
    Cheskis BJ; Freedman LP; Nagpal S
    Curr Opin Investig Drugs; 2006 Oct; 7(10):906-11. PubMed ID: 17086935
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Crystal structures of the vitamin D nuclear receptor liganded with the vitamin D side chain analogues calcipotriol and seocalcitol, receptor agonists of clinical importance. Insights into a structural basis for the switching of calcipotriol to a receptor antagonist by further side chain modification.
    Tocchini-Valentini G; Rochel N; Wurtz JM; Moras D
    J Med Chem; 2004 Apr; 47(8):1956-61. PubMed ID: 15055995
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Fine tuning of agonistic/antagonistic activity for vitamin D receptor by 22-alkyl chain length of ligands: 22S-Hexyl compound unexpectedly restored agonistic activity.
    Anami Y; Sakamaki Y; Itoh T; Inaba Y; Nakabayashi M; Ikura T; Ito N; Yamamoto K
    Bioorg Med Chem; 2015 Nov; 23(22):7274-81. PubMed ID: 26515040
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Response element and coactivator-mediated conformational change of the vitamin D(3) receptor permits sensitive interaction with agonists.
    Herdick M; Bury Y; Quack M; Uskokovic MR; Polly P; Carlberg C
    Mol Pharmacol; 2000 Jun; 57(6):1206-17. PubMed ID: 10825392
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Applications of the Vitamin D sterol-Vitamin D receptor (VDR) conformational ensemble model.
    Mizwicki MT; Bishop JE; Norman AW
    Steroids; 2005; 70(5-7):464-71. PubMed ID: 15862832
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Molecular mechanism of the vitamin D antagonistic actions of (23S)-25-dehydro-1alpha-hydroxyvitamin D3-26,23-lactone depends on the primary structure of the carboxyl-terminal region of the vitamin d receptor.
    Ochiai E; Miura D; Eguchi H; Ohara S; Takenouchi K; Azuma Y; Kamimura T; Norman AW; Ishizuka S
    Mol Endocrinol; 2005 May; 19(5):1147-57. PubMed ID: 15650022
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Vitamin D receptor (VDR)-mediated actions of 1α,25(OH)₂vitamin D₃: genomic and non-genomic mechanisms.
    Haussler MR; Jurutka PW; Mizwicki M; Norman AW
    Best Pract Res Clin Endocrinol Metab; 2011 Aug; 25(4):543-59. PubMed ID: 21872797
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A structural basis for the species-specific antagonism of 26,23-lactones on vitamin D signaling.
    Peräkylä M; Molnár F; Carlberg C
    Chem Biol; 2004 Aug; 11(8):1147-56. PubMed ID: 15324816
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure-function relationships of vitamin D including ligand recognition by the vitamin D receptor.
    Yamada S; Shimizu M; Yamamoto K
    Med Res Rev; 2003 Jan; 23(1):89-115. PubMed ID: 12424754
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structure-activity relationship of nonsecosteroidal vitamin D receptor modulators.
    Yamada S; Makishima M
    Trends Pharmacol Sci; 2014 Jul; 35(7):324-37. PubMed ID: 24865943
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Functionalization at C-12 of 1alpha,25-dihydroxyvitamin D(3) strongly modulates the affinity for the vitamin D receptor (VDR).
    González-Avión XC; Mouriño A
    Org Lett; 2003 Jun; 5(13):2291-3. PubMed ID: 12816431
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Crystal structures of hereditary vitamin D-resistant rickets-associated vitamin D receptor mutants R270L and W282R bound to 1,25-dihydroxyvitamin D3 and synthetic ligands.
    Nakabayashi M; Tsukahara Y; Iwasaki-Miyamoto Y; Mihori-Shimazaki M; Yamada S; Inaba S; Oda M; Shimizu M; Makishima M; Tokiwa H; Ikura T; Ito N
    J Med Chem; 2013 Sep; 56(17):6745-60. PubMed ID: 23944708
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.