BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

278 related articles for article (PubMed ID: 22451653)

  • 1. Siglec-15 protein regulates formation of functional osteoclasts in concert with DNAX-activating protein of 12 kDa (DAP12).
    Ishida-Kitagawa N; Tanaka K; Bao X; Kimura T; Miura T; Kitaoka Y; Hayashi K; Sato M; Maruoka M; Ogawa T; Miyoshi J; Takeya T
    J Biol Chem; 2012 May; 287(21):17493-17502. PubMed ID: 22451653
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Siglec-15 regulates osteoclast differentiation by modulating RANKL-induced phosphatidylinositol 3-kinase/Akt and Erk pathways in association with signaling Adaptor DAP12.
    Kameda Y; Takahata M; Komatsu M; Mikuni S; Hatakeyama S; Shimizu T; Angata T; Kinjo M; Minami A; Iwasaki N
    J Bone Miner Res; 2013 Dec; 28(12):2463-75. PubMed ID: 23677868
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A Comprehensive Review of Immunoreceptor Regulation of Osteoclasts.
    Humphrey MB; Nakamura MC
    Clin Rev Allergy Immunol; 2016 Aug; 51(1):48-58. PubMed ID: 26573914
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Early estrogen-induced gene 1, a novel RANK signaling component, is essential for osteoclastogenesis.
    Choi HK; Kang HR; Jung E; Kim TE; Lin JJ; Lee SY
    Cell Res; 2013 Apr; 23(4):524-36. PubMed ID: 23478294
    [TBL] [Abstract][Full Text] [Related]  

  • 5. TREM2, a DAP12-associated receptor, regulates osteoclast differentiation and function.
    Humphrey MB; Daws MR; Spusta SC; Niemi EC; Torchia JA; Lanier LL; Seaman WE; Nakamura MC
    J Bone Miner Res; 2006 Feb; 21(2):237-45. PubMed ID: 16418779
    [TBL] [Abstract][Full Text] [Related]  

  • 6. DOK3 Modulates Bone Remodeling by Negatively Regulating Osteoclastogenesis and Positively Regulating Osteoblastogenesis.
    Cai X; Xing J; Long CL; Peng Q; Humphrey MB
    J Bone Miner Res; 2017 Nov; 32(11):2207-2218. PubMed ID: 28650106
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Siglec-15 is a potential therapeutic target for postmenopausal osteoporosis.
    Kameda Y; Takahata M; Mikuni S; Shimizu T; Hamano H; Angata T; Hatakeyama S; Kinjo M; Iwasaki N
    Bone; 2015 Feb; 71():217-26. PubMed ID: 25460183
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Interleukin-27 inhibits human osteoclastogenesis by abrogating RANKL-mediated induction of nuclear factor of activated T cells c1 and suppressing proximal RANK signaling.
    Kalliolias GD; Zhao B; Triantafyllopoulou A; Park-Min KH; Ivashkiv LB
    Arthritis Rheum; 2010 Feb; 62(2):402-13. PubMed ID: 20112358
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Involvement of Siglec-15 in regulating RAP1/RAC signaling in cytoskeletal remodeling in osteoclasts mediated by macrophage colony-stimulating factor.
    Kobayashi H; Terkawi MA; Ota M; Hasegawa T; Yamamoto T; Shimizu T; Sato D; Fujita R; Murakami T; Amizuka N; Iwasaki N; Takahata M
    Bone Res; 2024 Jun; 12(1):35. PubMed ID: 38849345
    [TBL] [Abstract][Full Text] [Related]  

  • 10. CSTA plays a role in osteoclast formation and bone resorption by mediating the DAP12/TREM2 pathway.
    Wei R; Zhang L; Hu W; Wu J; Zhang W
    Biochem Biophys Res Commun; 2022 Oct; 627():12-20. PubMed ID: 36007331
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Siglec-15, a member of the sialic acid-binding lectin, is a novel regulator for osteoclast differentiation.
    Hiruma Y; Hirai T; Tsuda E
    Biochem Biophys Res Commun; 2011 Jun; 409(3):424-9. PubMed ID: 21586272
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The immunomodulatory adapter proteins DAP12 and Fc receptor gamma-chain (FcRgamma) regulate development of functional osteoclasts through the Syk tyrosine kinase.
    Mócsai A; Humphrey MB; Van Ziffle JA; Hu Y; Burghardt A; Spusta SC; Majumdar S; Lanier LL; Lowell CA; Nakamura MC
    Proc Natl Acad Sci U S A; 2004 Apr; 101(16):6158-63. PubMed ID: 15073337
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The signaling adapter protein DAP12 regulates multinucleation during osteoclast development.
    Humphrey MB; Ogasawara K; Yao W; Spusta SC; Daws MR; Lane NE; Lanier LL; Nakamura MC
    J Bone Miner Res; 2004 Feb; 19(2):224-34. PubMed ID: 14969392
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation of ITAM adaptor molecules and their receptors by inhibition of calcineurin-NFAT signalling during late stage osteoclast differentiation.
    Zawawi MS; Dharmapatni AA; Cantley MD; McHugh KP; Haynes DR; Crotti TN
    Biochem Biophys Res Commun; 2012 Oct; 427(2):404-9. PubMed ID: 23000414
    [TBL] [Abstract][Full Text] [Related]  

  • 15. High dose M-CSF partially rescues the Dap12-/- osteoclast phenotype.
    Faccio R; Zou W; Colaianni G; Teitelbaum SL; Ross FP
    J Cell Biochem; 2003 Dec; 90(5):871-83. PubMed ID: 14624447
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Osthole inhibits osteoclasts formation and bone resorption by regulating NF-κB signaling and NFATc1 activations stimulated by RANKL.
    Ma Y; Wang L; Zheng S; Xu J; Pan Y; Tu P; Sun J; Guo Y
    J Cell Biochem; 2019 Sep; 120(9):16052-16061. PubMed ID: 31081953
    [TBL] [Abstract][Full Text] [Related]  

  • 17. p62 ubiquitin binding-associated domain mediated the receptor activator of nuclear factor-kappaB ligand-induced osteoclast formation: a new insight into the pathogenesis of Paget's disease of bone.
    Yip KH; Feng H; Pavlos NJ; Zheng MH; Xu J
    Am J Pathol; 2006 Aug; 169(2):503-14. PubMed ID: 16877352
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sialic acid-binding immunoglobulin-like lectin 15 (Siglec-15) mediates periarticular bone loss, but not joint destruction, in murine antigen-induced arthritis.
    Shimizu T; Takahata M; Kameda Y; Endo T; Hamano H; Hiratsuka S; Ota M; Iwasaki N
    Bone; 2015 Oct; 79():65-70. PubMed ID: 26027508
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Signal adaptor DAP10 associates with MDL-1 and triggers osteoclastogenesis in cooperation with DAP12.
    Inui M; Kikuchi Y; Aoki N; Endo S; Maeda T; Sugahara-Tobinai A; Fujimura S; Nakamura A; Kumanogoh A; Colonna M; Takai T
    Proc Natl Acad Sci U S A; 2009 Mar; 106(12):4816-21. PubMed ID: 19251634
    [TBL] [Abstract][Full Text] [Related]  

  • 20. PDK1 is important lipid kinase for RANKL-induced osteoclast formation and function via the regulation of the Akt-GSK3β-NFATc1 signaling cascade.
    Xiao D; Zhou Q; Gao Y; Cao B; Zhang Q; Zeng G; Zong S
    J Cell Biochem; 2020 Nov; 121(11):4542-4557. PubMed ID: 32048762
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.