These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

150 related articles for article (PubMed ID: 22452455)

  • 1. Ontogeny of hepatic glucuronidation; methods and results.
    Krekels EH; Danhof M; Tibboel D; Knibbe CA
    Curr Drug Metab; 2012 Jul; 13(6):728-43. PubMed ID: 22452455
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Developmental aspects of human hepatic drug glucuronidation in young children and adults.
    Strassburg CP; Strassburg A; Kneip S; Barut A; Tukey RH; Rodeck B; Manns MP
    Gut; 2002 Feb; 50(2):259-65. PubMed ID: 11788570
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Relative importance of intestinal and hepatic glucuronidation-impact on the prediction of drug clearance.
    Cubitt HE; Houston JB; Galetin A
    Pharm Res; 2009 May; 26(5):1073-83. PubMed ID: 19184618
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Glucuronidation in humans. Pharmacogenetic and developmental aspects.
    de Wildt SN; Kearns GL; Leeder JS; van den Anker JN
    Clin Pharmacokinet; 1999 Jun; 36(6):439-52. PubMed ID: 10427468
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Transcriptional regulation of human UDP-glucuronosyltransferase genes.
    Hu DG; Meech R; McKinnon RA; Mackenzie PI
    Drug Metab Rev; 2014 Nov; 46(4):421-58. PubMed ID: 25336387
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The prediction of drug-glucuronidation parameters in humans: UDP-glucuronosyltransferase enzyme-selective substrate and inhibitor probes for reaction phenotyping and in vitro-in vivo extrapolation of drug clearance and drug-drug interaction potential.
    Miners JO; Mackenzie PI; Knights KM
    Drug Metab Rev; 2010 Feb; 42(1):196-208. PubMed ID: 19795925
    [TBL] [Abstract][Full Text] [Related]  

  • 7. In vitro-in vivo correlation for drugs and other compounds eliminated by glucuronidation in humans: pitfalls and promises.
    Miners JO; Knights KM; Houston JB; Mackenzie PI
    Biochem Pharmacol; 2006 May; 71(11):1531-9. PubMed ID: 16455060
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Enzyme kinetics of uridine diphosphate glucuronosyltransferases (UGTs).
    Zhou J; Miners JO
    Methods Mol Biol; 2014; 1113():203-28. PubMed ID: 24523115
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Use of cloned and expressed human liver UDP-glucuronosyltransferases for analysis of drug glucuronide formation and assessment of drug toxicity.
    Burchell B; Ebner T; Baird S; Bin Senafi S; Clarke D; Brierley C; Sutherland L
    Environ Health Perspect; 1994 Nov; 102 Suppl 9(Suppl 9):19-23. PubMed ID: 7698078
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Multiplexed Targeted Quantitative Proteomics Predicts Hepatic Glucuronidation Potential.
    Margaillan G; Rouleau M; Klein K; Fallon JK; Caron P; Villeneuve L; Smith PC; Zanger UM; Guillemette C
    Drug Metab Dispos; 2015 Sep; 43(9):1331-5. PubMed ID: 26076694
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Male rat hepatic UDP-glucuronosyltransferase activity toward thyroxine. Activation and induction properties--relation with thyroxine plasma disappearance rate.
    de Sandro V; Catinot R; Kriszt W; Cordier A; Richert L
    Biochem Pharmacol; 1992 Apr; 43(7):1563-9. PubMed ID: 1567478
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Prediction of hepatic and intestinal glucuronidation using in vitro-in vivo extrapolation.
    Naritomi Y; Nakamori F; Furukawa T; Tabata K
    Drug Metab Pharmacokinet; 2015 Feb; 30(1):21-9. PubMed ID: 25760528
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Optimization of Experimental Conditions of Automated Glucuronidation Assays in Human Liver Microsomes Using a Cocktail Approach and Ultra-High Performance Liquid Chromatography-Tandem Mass Spectrometry.
    Badée J; Qiu N; Parrott N; Collier AC; Schmidt S; Fowler S
    Drug Metab Dispos; 2019 Feb; 47(2):124-134. PubMed ID: 30478159
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Isoform-selective probe substrates for in vitro studies of human UDP-glucuronosyltransferases.
    Court MH
    Methods Enzymol; 2005; 400():104-16. PubMed ID: 16399346
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Drug and xenobiotic glucuronidation catalysed by cloned human liver UDP-Glucuronosyltransferases stably expressed in tissue culture cell lines.
    Wooster R; Ebner T; Sutherland L; Clarke D; Burchell B
    Toxicology; 1993 Oct; 82(1-3):119-29. PubMed ID: 8236271
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of UDP-glucuronosyltransferases responsible for the glucuronidation of darexaban, an oral factor Xa inhibitor, in human liver and intestine.
    Shiraga T; Yajima K; Suzuki K; Suzuki K; Hashimoto T; Iwatsubo T; Miyashita A; Usui T
    Drug Metab Dispos; 2012 Feb; 40(2):276-82. PubMed ID: 22031623
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Quantitative profiling of human renal UDP-glucuronosyltransferases and glucuronidation activity: a comparison of normal and tumoral kidney tissues.
    Margaillan G; Rouleau M; Fallon JK; Caron P; Villeneuve L; Turcotte V; Smith PC; Joy MS; Guillemette C
    Drug Metab Dispos; 2015 Apr; 43(4):611-9. PubMed ID: 25650382
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes.
    Iyer L; King CD; Whitington PF; Green MD; Roy SK; Tephly TR; Coffman BL; Ratain MJ
    J Clin Invest; 1998 Feb; 101(4):847-54. PubMed ID: 9466980
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Relevance of UDP-glucuronosyltransferase polymorphisms for drug dosing: A quantitative systematic review.
    Stingl JC; Bartels H; Viviani R; Lehmann ML; Brockmöller J
    Pharmacol Ther; 2014 Jan; 141(1):92-116. PubMed ID: 24076267
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The effects of UDP-sugars, UDP and Mg
    Walia G; Smith AD; Riches Z; Collier AC; Coughtrie MWH
    Xenobiotica; 2018 Sep; 48(9):882-890. PubMed ID: 28868965
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.