165 related articles for article (PubMed ID: 22455313)
1. P3-P3' residues flanking scissile bonds in factor VIII modulate rates of substrate cleavage and procofactor activation by thrombin.
Newell-Caito JL; Griffiths AE; Fay PJ
Biochemistry; 2012 Apr; 51(16):3451-9. PubMed ID: 22455313
[TBL] [Abstract][Full Text] [Related]
2. Sequences flanking Arg336 in factor VIIIa modulate factor Xa-catalyzed cleavage rates at this site and cofactor function.
DeAngelis JP; Wakabayashi H; Fay PJ
J Biol Chem; 2012 May; 287(19):15409-17. PubMed ID: 22411993
[TBL] [Abstract][Full Text] [Related]
3. Residues surrounding Arg336 and Arg562 contribute to the disparate rates of proteolysis of factor VIIIa catalyzed by activated protein C.
Varfaj F; Wakabayashi H; Fay PJ
J Biol Chem; 2007 Jul; 282(28):20264-72. PubMed ID: 17519239
[TBL] [Abstract][Full Text] [Related]
4. Residues flanking scissile bonds in Factor VIII modulate rates of cleavage and proteolytic activation catalyzed by Factor Xa.
Griffiths AE; Wintermute J; Newell-Caito JL; Fay PJ
Biochemistry; 2013 Nov; 52(45):8060-8. PubMed ID: 24128092
[TBL] [Abstract][Full Text] [Related]
5. An in silico and in vitro approach to elucidate the impact of residues flanking the cleavage scissile bonds of FVIII.
Pezeshkpoor B; Schreck U; Biswas A; Driesen J; Berkemeier AC; Pavlova A; Müller J; Oldenburg J
PLoS One; 2017; 12(7):e0180456. PubMed ID: 28683085
[TBL] [Abstract][Full Text] [Related]
6. The role of P4-P3' residues flanking Arg336 in facilitating activated protein C-catalyzed cleavage and inactivation of factor VIIIa.
DeAngelis JP; Varfaj F; Wakabayashi H; Fay PJ
Thromb Res; 2011 Nov; 128(5):470-6. PubMed ID: 21470668
[TBL] [Abstract][Full Text] [Related]
7. Combining mutations that modulate inter-subunit interactions and proteolytic inactivation enhance the stability of factor VIIIa.
Wakabayashi H; Wintermute JM; Fay PJ
Thromb Haemost; 2014 Jul; 112(1):43-52. PubMed ID: 24599523
[TBL] [Abstract][Full Text] [Related]
8. Cleavage at Arg-1689 influences heavy chain cleavages during thrombin-catalyzed activation of factor VIII.
Newell JL; Fay PJ
J Biol Chem; 2009 Apr; 284(17):11080-9. PubMed ID: 19240027
[TBL] [Abstract][Full Text] [Related]
9. Acidic Region Residues 1680-1684 in the A3 Domain of Factor VIII Contain a Thrombin-Interactive Site Responsible for Proteolytic Cleavage at Arg1689.
Nakajima Y; Minami H; Nogami K
Thromb Haemost; 2021 Oct; 121(10):1274-1288. PubMed ID: 33592631
[TBL] [Abstract][Full Text] [Related]
10. Proteolysis at Arg740 facilitates subsequent bond cleavages during thrombin-catalyzed activation of factor VIII.
Newell JL; Fay PJ
J Biol Chem; 2007 Aug; 282(35):25367-75. PubMed ID: 17595160
[TBL] [Abstract][Full Text] [Related]
11. Cleavage of factor VIII light chain is required for maximal generation of factor VIIIa activity.
Regan LM; Fay PJ
J Biol Chem; 1995 Apr; 270(15):8546-52. PubMed ID: 7721754
[TBL] [Abstract][Full Text] [Related]
12. Exosite-interactive regions in the A1 and A2 domains of factor VIII facilitate thrombin-catalyzed cleavage of heavy chain.
Nogami K; Zhou Q; Myles T; Leung LL; Wakabayashi H; Fay PJ
J Biol Chem; 2005 May; 280(18):18476-87. PubMed ID: 15746105
[TBL] [Abstract][Full Text] [Related]
13. Acidic residues C-terminal to the A2 domain facilitate thrombin-catalyzed activation of factor VIII.
Newell JL; Fay PJ
Biochemistry; 2008 Aug; 47(33):8786-95. PubMed ID: 18642885
[TBL] [Abstract][Full Text] [Related]
14. The C-terminal acidic region in the A1 domain of factor VIII facilitates thrombin-catalyzed activation and cleavage at Arg
Nakajima Y; Nogami K
J Thromb Haemost; 2021 Mar; 19(3):677-688. PubMed ID: 33369157
[TBL] [Abstract][Full Text] [Related]
15. Modification of interdomain interfaces within the A3C1C2 subunit of factor VIII affects its stability and activity.
Wakabayashi H; Fay PJ
Biochemistry; 2013 Jun; 52(22):3921-9. PubMed ID: 23659383
[TBL] [Abstract][Full Text] [Related]
16. Contribution of factor VIII light-chain residues 2007-2016 to an activated protein C-interactive site.
Takeyama M; Wakabayashi H; Fay PJ
Thromb Haemost; 2013 Feb; 109(2):187-98. PubMed ID: 23224054
[TBL] [Abstract][Full Text] [Related]
17. Mild hemophilia A caused by increased rate of factor VIII A2 subunit dissociation: evidence for nonproteolytic inactivation of factor VIIIa in vivo.
Pipe SW; Eickhorst AN; McKinley SH; Saenko EL; Kaufman RJ
Blood; 1999 Jan; 93(1):176-83. PubMed ID: 9864159
[TBL] [Abstract][Full Text] [Related]
18. Cofactor activity in factor VIIIa of the blood clotting pathway is stabilized by an interdomain bond between His281 and Ser524 formed in factor VIII.
Wakabayashi H; Monaghan M; Fay PJ
J Biol Chem; 2014 May; 289(20):14020-9. PubMed ID: 24692542
[TBL] [Abstract][Full Text] [Related]
19. Thrombin-catalyzed activation of factor VIII with His substituted for Arg372 at the P1 site.
Nogami K; Zhou Q; Wakabayashi H; Fay PJ
Blood; 2005 Jun; 105(11):4362-8. PubMed ID: 15705787
[TBL] [Abstract][Full Text] [Related]
20. Characterisation of an antibody specific for coagulation factor VIII that enhances factor VIII activity.
Takeyama M; Nogami K; Matsumoto T; Soeda T; Suzuki T; Hattori K; Shima M
Thromb Haemost; 2010 Jan; 103(1):94-102. PubMed ID: 20062922
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
