BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

285 related articles for article (PubMed ID: 22457811)

  • 1. Kindlins, integrin activation and the regulation of talin recruitment to αIIbβ3.
    Kahner BN; Kato H; Banno A; Ginsberg MH; Shattil SJ; Ye F
    PLoS One; 2012; 7(3):e34056. PubMed ID: 22457811
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Kindlin-1 and -2 directly bind the C-terminal region of beta integrin cytoplasmic tails and exert integrin-specific activation effects.
    Harburger DS; Bouaouina M; Calderwood DA
    J Biol Chem; 2009 Apr; 284(17):11485-97. PubMed ID: 19240021
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A conserved lipid-binding loop in the kindlin FERM F1 domain is required for kindlin-mediated αIIbβ3 integrin coactivation.
    Bouaouina M; Goult BT; Huet-Calderwood C; Bate N; Brahme NN; Barsukov IL; Critchley DR; Calderwood DA
    J Biol Chem; 2012 Mar; 287(10):6979-90. PubMed ID: 22235127
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ADAP interactions with talin and kindlin promote platelet integrin αIIbβ3 activation and stable fibrinogen binding.
    Kasirer-Friede A; Kang J; Kahner B; Ye F; Ginsberg MH; Shattil SJ
    Blood; 2014 May; 123(20):3156-65. PubMed ID: 24523237
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Kindlin supports platelet integrin αIIbβ3 activation by interacting with paxillin.
    Gao J; Huang M; Lai J; Mao K; Sun P; Cao Z; Hu Y; Zhang Y; Schulte ML; Jin C; Wang J; White GC; Xu Z; Ma YQ
    J Cell Sci; 2017 Nov; 130(21):3764-3775. PubMed ID: 28954813
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Integrin αII b tail distal of GFFKR participates in inside-out αII b β3 activation.
    Li A; Guo Q; Kim C; Hu W; Ye F
    J Thromb Haemost; 2014 Jul; 12(7):1145-55. PubMed ID: 24837519
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The mechanism of kindlin-mediated activation of integrin αIIbβ3.
    Ye F; Petrich BG; Anekal P; Lefort CT; Kasirer-Friede A; Shattil SJ; Ruppert R; Moser M; Fässler R; Ginsberg MH
    Curr Biol; 2013 Nov; 23(22):2288-2295. PubMed ID: 24210614
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The extreme C-terminal region of kindlin-2 is critical to its regulation of integrin activation.
    Hirbawi J; Bialkowska K; Bledzka KM; Liu J; Fukuda K; Qin J; Plow EF
    J Biol Chem; 2017 Aug; 292(34):14258-14269. PubMed ID: 28652408
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Agonist stimulation, talin-1, and kindlin-3 are crucial for α(IIb)β(3) activation in a human megakaryoblastic cell line, CMK.
    Nakazawa T; Tadokoro S; Kamae T; Kiyomizu K; Kashiwagi H; Honda S; Kanakura Y; Tomiyama Y
    Exp Hematol; 2013 Jan; 41(1):79-90.e1. PubMed ID: 23022222
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Site-specific phosphorylation of kindlin-3 protein regulates its capacity to control cellular responses mediated by integrin αIIbβ3.
    Bialkowska K; Byzova TV; Plow EF
    J Biol Chem; 2015 Mar; 290(10):6226-42. PubMed ID: 25609252
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cooperative role of the membrane-proximal and -distal residues of the integrin beta3 cytoplasmic domain in regulation of talin-mediated alpha IIb beta3 activation.
    Hato T; Yamanouchi J; Tamura T; Yakushijin Y; Sakai I; Yasukawa M
    J Biol Chem; 2008 Feb; 283(9):5662-8. PubMed ID: 18174155
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The structure of the N-terminus of kindlin-1: a domain important for alphaiibbeta3 integrin activation.
    Goult BT; Bouaouina M; Harburger DS; Bate N; Patel B; Anthis NJ; Campbell ID; Calderwood DA; Barsukov IL; Roberts GC; Critchley DR
    J Mol Biol; 2009 Dec; 394(5):944-56. PubMed ID: 19804783
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Role of the Helix in Talin F3 Domain (F3 Helix) in Talin-Mediated Integrin Activation.
    Li A; Guo Q; Wei A; Zhou Y; Hu W
    Cell Biochem Biophys; 2017 Mar; 75(1):79-86. PubMed ID: 28101696
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mechanisms and consequences of agonist-induced talin recruitment to platelet integrin alphaIIbbeta3.
    Watanabe N; Bodin L; Pandey M; Krause M; Coughlin S; Boussiotis VA; Ginsberg MH; Shattil SJ
    J Cell Biol; 2008 Jun; 181(7):1211-22. PubMed ID: 18573917
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Kindlin Assists Talin to Promote Integrin Activation.
    Haydari Z; Shams H; Jahed Z; Mofrad MRK
    Biophys J; 2020 Apr; 118(8):1977-1991. PubMed ID: 32191864
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure basis of the FERM domain of kindlin-3 in supporting integrin αIIbβ3 activation in platelets.
    Sun J; Xiao D; Ni Y; Zhang T; Cao Z; Xu Z; Nguyen H; Zhang J; White GC; Ding J; Ma YQ; Xu Z
    Blood Adv; 2020 Jul; 4(13):3128-3135. PubMed ID: 32649767
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tyrosine phosphorylation of integrin beta3 regulates kindlin-2 binding and integrin activation.
    Bledzka K; Bialkowska K; Nie H; Qin J; Byzova T; Wu C; Plow EF; Ma YQ
    J Biol Chem; 2010 Oct; 285(40):30370-4. PubMed ID: 20702409
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The talin rod IBS2 alpha-helix interacts with the beta3 integrin cytoplasmic tail membrane-proximal helix by establishing charge complementary salt bridges.
    Rodius S; Chaloin O; Moes M; Schaffner-Reckinger E; Landrieu I; Lippens G; Lin M; Zhang J; Kieffer N
    J Biol Chem; 2008 Aug; 283(35):24212-23. PubMed ID: 18577523
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Integrity of kindlin-2 FERM subdomains is required for supporting integrin activation.
    Xu Z; Gao J; Hong J; Ma YQ
    Biochem Biophys Res Commun; 2013 May; 434(2):382-7. PubMed ID: 23578664
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Optogenetics-based localization of talin to the plasma membrane promotes activation of β3 integrins.
    Liao Z; Gingras AR; Lagarrigue F; Ginsberg MH; Shattil SJ
    J Biol Chem; 2021; 296():100675. PubMed ID: 33865854
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.