BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

251 related articles for article (PubMed ID: 22458682)

  • 1. Progress in the development of anti-hepatitis C virus nucleoside and nucleotide prodrugs.
    Madela K; McGuigan C
    Future Med Chem; 2012 Apr; 4(5):625-50. PubMed ID: 22458682
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Nucleoside, nucleotide, and non-nucleoside inhibitors of hepatitis C virus NS5B RNA-dependent RNA-polymerase.
    Sofia MJ; Chang W; Furman PA; Mosley RT; Ross BS
    J Med Chem; 2012 Mar; 55(6):2481-531. PubMed ID: 22185586
    [No Abstract]   [Full Text] [Related]  

  • 3. Preparation and biological evaluation of 1'-cyano-2'-C-methyl pyrimidine nucleosides as HCV NS5B polymerase inhibitors.
    Mish MR; Cho A; Kirschberg T; Xu J; Zonte CS; Fenaux M; Park Y; Babusis D; Feng JY; Ray AS; Kim CU
    Bioorg Med Chem Lett; 2014 Jul; 24(14):3092-5. PubMed ID: 24907145
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Nucleoside analog inhibitors of hepatitis C virus replication.
    Carroll SS; Olsen DB
    Infect Disord Drug Targets; 2006 Mar; 6(1):17-29. PubMed ID: 16787301
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Non-nucleoside inhibitors of the HCV NS5B polymerase: progress in the discovery and development of novel agents for the treatment of HCV infections.
    Beaulieu PL
    Curr Opin Investig Drugs; 2007 Aug; 8(8):614-34. PubMed ID: 17668364
    [TBL] [Abstract][Full Text] [Related]  

  • 6. New NS5B polymerase inhibitors for hepatitis C.
    Legrand-Abravanel F; Nicot F; Izopet J
    Expert Opin Investig Drugs; 2010 Aug; 19(8):963-75. PubMed ID: 20629614
    [TBL] [Abstract][Full Text] [Related]  

  • 7. NS5B RNA dependent RNA polymerase inhibitors: the promising approach to treat hepatitis C virus infections.
    Deore RR; Chern JW
    Curr Med Chem; 2010; 17(32):3806-26. PubMed ID: 20858218
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and antiviral properties of novel tetracyclic nucleoside inhibitors of hepatitis C NS5B polymerase.
    Di Francesco ME; Avolio S; Dessole G; Koch U; Pompei M; Pucci V; Rowley M; Summa V
    Nucleosides Nucleotides Nucleic Acids; 2012; 31(8):592-607. PubMed ID: 22908950
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Discovery of a 2'-fluoro-2'-C-methyl C-nucleotide HCV polymerase inhibitor and a phosphoramidate prodrug with favorable properties.
    Kirschberg TA; Metobo S; Clarke MO; Aktoudianakis V; Babusis D; Barauskas O; Birkus G; Butler T; Byun D; Chin G; Doerffler E; Edwards TE; Fenaux M; Lee R; Lew W; Mish MR; Murakami E; Park Y; Squires NH; Tirunagari N; Wang T; Whitcomb M; Xu J; Yang H; Ye H; Zhang L; Appleby TC; Feng JY; Ray AS; Cho A; Kim CU
    Bioorg Med Chem Lett; 2017 Apr; 27(8):1840-1847. PubMed ID: 28274633
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Current perspective of HCV NS5B inhibitors: a review.
    Patil VM; Gupta SP; Samanta S; Masand N
    Curr Med Chem; 2011; 18(36):5564-97. PubMed ID: 22172066
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Non-nucleoside inhibitors of the hepatitis C virus NS5B polymerase: discovery and preliminary SAR of benzimidazole derivatives.
    Beaulieu PL; Bös M; Bousquet Y; Fazal G; Gauthier J; Gillard J; Goulet S; LaPlante S; Poupart MA; Lefebvre S; McKercher G; Pellerin C; Austel V; Kukolj G
    Bioorg Med Chem Lett; 2004 Jan; 14(1):119-24. PubMed ID: 14684311
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of hepatitis C virus replication by GS-6620, a potent C-nucleoside monophosphate prodrug.
    Feng JY; Cheng G; Perry J; Barauskas O; Xu Y; Fenaux M; Eng S; Tirunagari N; Peng B; Yu M; Tian Y; Lee YJ; Stepan G; Lagpacan LL; Jin D; Hung M; Ku KS; Han B; Kitrinos K; Perron M; Birkus G; Wong KA; Zhong W; Kim CU; Carey A; Cho A; Ray AS
    Antimicrob Agents Chemother; 2014; 58(4):1930-42. PubMed ID: 24419349
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Nucleoside analog inhibitors of hepatitis C viral replication: recent advances, challenges and trends.
    Furman PA; Lam AM; Murakami E
    Future Med Chem; 2009 Nov; 1(8):1429-52. PubMed ID: 21426058
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibitors of the HCV NS5B polymerase: new hope for the treatment of hepatitis C infections.
    Beaulieu PL; Tsantrizos YS
    Curr Opin Investig Drugs; 2004 Aug; 5(8):838-50. PubMed ID: 15600240
    [TBL] [Abstract][Full Text] [Related]  

  • 15. R-1626, a specific oral NS5B polymerase inhibitor of hepatitis C virus.
    Toniutto P; Fabris C; Bitetto D; Fumolo E; Fornasiere E; Pirisi M
    IDrugs; 2008 Oct; 11(10):738-49. PubMed ID: 18828074
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and anti-HCV activity of 3',4'-oxetane nucleosides.
    Chang W; Du J; Rachakonda S; Ross BS; Convers-Reignier S; Yau WT; Pons JF; Murakami E; Bao H; Steuer HM; Furman PA; Otto MJ; Sofia MJ
    Bioorg Med Chem Lett; 2010 Aug; 20(15):4539-43. PubMed ID: 20580554
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nucleotide prodrugs for HCV therapy.
    Sofia MJ
    Antivir Chem Chemother; 2011 Aug; 22(1):23-49. PubMed ID: 21860070
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discovery of β-d-2'-deoxy-2'-dichlorouridine nucleotide prodrugs as potent inhibitors of hepatitis C virus replication.
    Pinho P; Kalayanov G; Westerlind H; Rosenquist Å; Wähling H; Sund C; Almeida M; Ayesa S; Tejbrant J; Targett-Adams P; Eneroth A; Lindqvist A
    Bioorg Med Chem Lett; 2017 Aug; 27(15):3468-3471. PubMed ID: 28622881
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PSI-7851, a pronucleotide of beta-D-2'-deoxy-2'-fluoro-2'-C-methyluridine monophosphate, is a potent and pan-genotype inhibitor of hepatitis C virus replication.
    Lam AM; Murakami E; Espiritu C; Steuer HM; Niu C; Keilman M; Bao H; Zennou V; Bourne N; Julander JG; Morrey JD; Smee DF; Frick DN; Heck JA; Wang P; Nagarathnam D; Ross BS; Sofia MJ; Otto MJ; Furman PA
    Antimicrob Agents Chemother; 2010 Aug; 54(8):3187-96. PubMed ID: 20516278
    [TBL] [Abstract][Full Text] [Related]  

  • 20. HCV NS5B polymerase inhibitors.
    Burton JR; Everson GT
    Clin Liver Dis; 2009 Aug; 13(3):453-65. PubMed ID: 19628161
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.