BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

98 related articles for article (PubMed ID: 22459351)

  • 1. Insulin promotes proliferation, survival, and invasion in endometrial carcinoma by activating the MEK/ERK pathway.
    Wang Y; Zhu Y; Zhang L; Tian W; Hua S; Zhao J; Zhang H; Xue F
    Cancer Lett; 2012 Sep; 322(2):223-31. PubMed ID: 22459351
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mitogenic and anti-apoptotic effects of insulin in endometrial cancer are phosphatidylinositol 3-kinase/Akt dependent.
    Wang Y; Hua S; Tian W; Zhang L; Zhao J; Zhang H; Zhang W; Xue F
    Gynecol Oncol; 2012 Jun; 125(3):734-41. PubMed ID: 22426488
    [TBL] [Abstract][Full Text] [Related]  

  • 3. [Relationship between raf kinase inhibitor protein and metastasis of ovarian carcinoma].
    Wang Y; Yang J; Gao Y; Zhao XL; Li HZ; Yao Z
    Zhonghua Fu Chan Ke Za Zhi; 2009 Jul; 44(7):522-8. PubMed ID: 19957553
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The activation of MEK/ERK signaling pathway by bone morphogenetic protein 4 to increase hepatocellular carcinoma cell proliferation and migration.
    Chiu CY; Kuo KK; Kuo TL; Lee KT; Cheng KH
    Mol Cancer Res; 2012 Mar; 10(3):415-27. PubMed ID: 22241220
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Evidence that leptin through STAT and CREB signaling enhances cyclin D1 expression and promotes human endometrial cancer proliferation.
    Catalano S; Giordano C; Rizza P; Gu G; Barone I; Bonofiglio D; Giordano F; Malivindi R; Gaccione D; Lanzino M; De Amicis F; Andò S
    J Cell Physiol; 2009 Mar; 218(3):490-500. PubMed ID: 18988190
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Resistance to mitogen-activated protein kinase kinase (MEK) inhibitors correlates with up-regulation of the MEK/extracellular signal-regulated kinase pathway in hepatocellular carcinoma cells.
    Yip-Schneider MT; Klein PJ; Wentz SC; Zeni A; Menze A; Schmidt CM
    J Pharmacol Exp Ther; 2009 Jun; 329(3):1063-70. PubMed ID: 19258520
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PI3K-FRAP/mTOR pathway is critical for hepatocyte proliferation whereas MEK/ERK supports both proliferation and survival.
    Coutant A; Rescan C; Gilot D; Loyer P; Guguen-Guillouzo C; Baffet G
    Hepatology; 2002 Nov; 36(5):1079-88. PubMed ID: 12395317
    [TBL] [Abstract][Full Text] [Related]  

  • 8. p21WAF1 expression induced by MEK/ERK pathway activation or inhibition correlates with growth arrest, myogenic differentiation and onco-phenotype reversal in rhabdomyosarcoma cells.
    Ciccarelli C; Marampon F; Scoglio A; Mauro A; Giacinti C; De Cesaris P; Zani BM
    Mol Cancer; 2005 Dec; 4():41. PubMed ID: 16351709
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activation of the RAF/mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase pathway mediates apoptosis induced by chelerythrine in osteosarcoma.
    Yang R; Piperdi S; Gorlick R
    Clin Cancer Res; 2008 Oct; 14(20):6396-404. PubMed ID: 18927278
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of doxorubicin-induced autophagy in hepatocellular carcinoma Hep3B cells by sorafenib--the role of extracellular signal-regulated kinase counteraction.
    Manov I; Pollak Y; Broneshter R; Iancu TC
    FEBS J; 2011 Sep; 278(18):3494-507. PubMed ID: 21790999
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Autocrine stimulation of IGF1 in estrogen-induced growth of endometrial carcinoma cells: involvement of the mitogen-activated protein kinase pathway followed by up-regulation of cyclin D1 and cyclin E.
    Kashima H; Shiozawa T; Miyamoto T; Suzuki A; Uchikawa J; Kurai M; Konishi I
    Endocr Relat Cancer; 2009 Mar; 16(1):113-22. PubMed ID: 18852162
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Rictor regulates MMP-9 activity and invasion through Raf-1-MEK-ERK signaling pathway in glioma cells.
    Das G; Shiras A; Shanmuganandam K; Shastry P
    Mol Carcinog; 2011 Jun; 50(6):412-23. PubMed ID: 21557327
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Significant anti-proliferation of human endometrial cancer cells by combined treatment with a selective COX-2 inhibitor NS398 and specific MEK inhibitor U0126.
    Gao J; Niwa K; Takemura M; Sun W; Onogi K; Wu Y; Seishima M; Mori H; Tamaya T
    Int J Oncol; 2005 Mar; 26(3):737-44. PubMed ID: 15703831
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Adiponectin mediates antiproliferative and apoptotic responses in endometrial carcinoma by the AdipoRs/AMPK pathway.
    Zhang L; Wen K; Han X; Liu R; Qu Q
    Gynecol Oncol; 2015 May; 137(2):311-20. PubMed ID: 25703675
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Extracellular ATP activates the PLC/PKC/ERK signaling pathway through the P2Y2 purinergic receptor leading to the induction of early growth response 1 expression and the inhibition of viability in human endometrial stromal cells.
    Chang SJ; Tzeng CR; Lee YH; Tai CJ
    Cell Signal; 2008 Jul; 20(7):1248-55. PubMed ID: 18434089
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [Effects of extracellular signal-regulated kinase/mitogen-activated protein kinase signaling pathway activation on proliferation and cell cycle associated genes in human colon cancer cells].
    Wang X; Lu R; Fang JY
    Zhonghua Yi Xue Za Zhi; 2007 Apr; 87(14):982-6. PubMed ID: 17650425
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Role of RAF/MEK/ERK pathway, p-STAT-3 and Mcl-1 in sorafenib activity in human pancreatic cancer cell lines.
    Ulivi P; Arienti C; Amadori D; Fabbri F; Carloni S; Tesei A; Vannini I; Silvestrini R; Zoli W
    J Cell Physiol; 2009 Jul; 220(1):214-21. PubMed ID: 19288493
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Activation and role of MAP kinase-dependent pathways in retinal pigment epithelial cells: ERK and RPE cell proliferation.
    Hecquet C; Lefevre G; Valtink M; Engelmann K; Mascarelli F
    Invest Ophthalmol Vis Sci; 2002 Sep; 43(9):3091-8. PubMed ID: 12202534
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pharmacologic inhibition of RAF-->MEK-->ERK signaling elicits pancreatic cancer cell cycle arrest through induced expression of p27Kip1.
    Gysin S; Lee SH; Dean NM; McMahon M
    Cancer Res; 2005 Jun; 65(11):4870-80. PubMed ID: 15930308
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Caffeine inhibits the proliferation of liver cancer cells and activates the MEK/ERK/EGFR signalling pathway.
    Okano J; Nagahara T; Matsumoto K; Murawaki Y
    Basic Clin Pharmacol Toxicol; 2008 Jun; 102(6):543-51. PubMed ID: 18346049
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.