BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

178 related articles for article (PubMed ID: 22461520)

  • 1. EGF promotes neuroendocrine-like differentiation of prostate cancer cells in the presence of LY294002 through increased ErbB2 expression independent of the phosphatidylinositol 3-kinase-AKT pathway.
    Cortés MA; Cariaga-Martinez AE; Lobo MV; Martín Orozco RM; Motiño O; Rodríguez-Ubreva FJ; Angulo J; López-Ruiz P; Colás B
    Carcinogenesis; 2012 Jun; 33(6):1169-77. PubMed ID: 22461520
    [TBL] [Abstract][Full Text] [Related]  

  • 2. EGF prevents the neuroendocrine differentiation of LNCaP cells induced by serum deprivation: the modulator role of PI3K/Akt.
    Martín-Orozco RM; Almaraz-Pro C; Rodríguez-Ubreva FJ; Cortés MA; Ropero S; Colomer R; López-Ruiz P; Colás B
    Neoplasia; 2007 Aug; 9(8):614-24. PubMed ID: 17898861
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Long-term androgen-ablation causes increased resistance to PI3K/Akt pathway inhibition in prostate cancer cells.
    Pfeil K; Eder IE; Putz T; Ramoner R; Culig Z; Ueberall F; Bartsch G; Klocker H
    Prostate; 2004 Feb; 58(3):259-68. PubMed ID: 14743465
    [TBL] [Abstract][Full Text] [Related]  

  • 4. EGFR signaling pathway negatively regulates PSA expression and secretion via the PI3K-Akt pathway in LNCaP prostate cancer cells.
    Hakariya T; Shida Y; Sakai H; Kanetake H; Igawa T
    Biochem Biophys Res Commun; 2006 Mar; 342(1):92-100. PubMed ID: 16472761
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ErbB2-overexpressing human mammary carcinoma cells display an increased requirement for the phosphatidylinositol 3-kinase signaling pathway in anchorage-independent growth.
    Hermanto U; Zong CS; Wang LH
    Oncogene; 2001 Nov; 20(51):7551-62. PubMed ID: 11709727
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Akt/protein kinase B isoforms are differentially regulated by epidermal growth factor stimulation.
    Okano J; Gaslightwala I; Birnbaum MJ; Rustgi AK; Nakagawa H
    J Biol Chem; 2000 Oct; 275(40):30934-42. PubMed ID: 10908564
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of the PI3K/Akt pathway increases the chemosensitivity of gastric cancer to vincristine.
    Xie X; Tang B; Zhou J; Gao Q; Zhang P
    Oncol Rep; 2013 Aug; 30(2):773-82. PubMed ID: 23743572
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ErbB1 and prostate cancer: ErbB1 activity is essential for androgen-induced proliferation and protection from the apoptotic effects of LY294002.
    Tørring N; Dagnaes-Hansen F; Sørensen BS; Nexø E; Hynes NE
    Prostate; 2003 Jul; 56(2):142-9. PubMed ID: 12746839
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Epidermal growth factor up-regulates expression of transforming growth factor beta receptor type II in human dermal fibroblasts by phosphoinositide 3-kinase/Akt signaling pathway: Resistance to epidermal growth factor stimulation in scleroderma fibroblasts.
    Yamane K; Ihn H; Tamaki K
    Arthritis Rheum; 2003 Jun; 48(6):1652-66. PubMed ID: 12794834
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effect of estradiol on estrogen receptor-alpha gene expression and activity can be modulated by the ErbB2/PI 3-K/Akt pathway.
    Stoica GE; Franke TF; Moroni M; Mueller S; Morgan E; Iann MC; Winder AD; Reiter R; Wellstein A; Martin MB; Stoica A
    Oncogene; 2003 Sep; 22(39):7998-8011. PubMed ID: 12970748
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Androgens stimulate hypoxia-inducible factor 1 activation via autocrine loop of tyrosine kinase receptor/phosphatidylinositol 3'-kinase/protein kinase B in prostate cancer cells.
    Mabjeesh NJ; Willard MT; Frederickson CE; Zhong H; Simons JW
    Clin Cancer Res; 2003 Jul; 9(7):2416-25. PubMed ID: 12855613
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Complex impacts of PI3K/AKT inhibitors to androgen receptor gene expression in prostate cancer cells.
    Liu L; Dong X
    PLoS One; 2014; 9(10):e108780. PubMed ID: 25360799
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Activation of PI3K-Akt signaling pathway promotes prostate cancer cell invasion.
    Shukla S; Maclennan GT; Hartman DJ; Fu P; Resnick MI; Gupta S
    Int J Cancer; 2007 Oct; 121(7):1424-32. PubMed ID: 17551921
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of phosphatidylinositol 3-kinase/Akt signaling suppresses tumor cell proliferation and neuroendocrine marker expression in GI carcinoid tumors.
    Pitt SC; Chen H; Kunnimalaiyaan M
    Ann Surg Oncol; 2009 Oct; 16(10):2936-42. PubMed ID: 19588205
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Apoptosis-mediated medullary thyroid cancer growth suppression by the PI3K inhibitor LY294002.
    Kunnimalaiyaan M; Ndiaye M; Chen H
    Surgery; 2006 Dec; 140(6):1009-14; discussion 1014-5. PubMed ID: 17188151
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Estradiol rapidly activates Akt via the ErbB2 signaling pathway.
    Stoica GE; Franke TF; Wellstein A; Czubayko F; List HJ; Reiter R; Morgan E; Martin MB; Stoica A
    Mol Endocrinol; 2003 May; 17(5):818-30. PubMed ID: 12554767
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Serotonin activates MAP kinase and PI3K/Akt signaling pathways in prostate cancer cell lines.
    Dizeyi N; Hedlund P; Bjartell A; Tinzl M; Austild-Taskén K; Abrahamsson PA
    Urol Oncol; 2011; 29(4):436-45. PubMed ID: 19926313
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics.
    Zhong H; Chiles K; Feldser D; Laughner E; Hanrahan C; Georgescu MM; Simons JW; Semenza GL
    Cancer Res; 2000 Mar; 60(6):1541-5. PubMed ID: 10749120
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of PI3K signaling in survival and progression of LNCaP prostate cancer cells to the androgen refractory state.
    Murillo H; Huang H; Schmidt LJ; Smith DI; Tindall DJ
    Endocrinology; 2001 Nov; 142(11):4795-805. PubMed ID: 11606446
    [TBL] [Abstract][Full Text] [Related]  

  • 20. LY294002 inhibits the malignant phenotype of osteosarcoma cells by modulating the phosphatidylinositol 3‑kinase/Akt/fatty acid synthase signaling pathway in vitro.
    Zhou Y; Zhu LB; Peng AF; Wang TF; Long XH; Gao S; Zhou RP; Liu ZL
    Mol Med Rep; 2015 Feb; 11(2):1352-7. PubMed ID: 25351625
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.