These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

780 related articles for article (PubMed ID: 22461522)

  • 1. Folate deprivation enhances invasiveness of human colon cancer cells mediated by activation of sonic hedgehog signaling through promoter hypomethylation and cross action with transcription nuclear factor-kappa B pathway.
    Wang TP; Hsu SH; Feng HC; Huang RF
    Carcinogenesis; 2012 Jun; 33(6):1158-68. PubMed ID: 22461522
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The sonic hedgehog signaling pathway stimulates anaplastic thyroid cancer cell motility and invasiveness by activating Akt and c-Met.
    Williamson AJ; Doscas ME; Ye J; Heiden KB; Xing M; Li Y; Prinz RA; Xu X
    Oncotarget; 2016 Mar; 7(9):10472-85. PubMed ID: 26859575
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Low folate metabolic stress reprograms DNA methylation-activated sonic hedgehog signaling to mediate cancer stem cell-like signatures and invasive tumour stage-specific malignancy of human colorectal cancers.
    Feng HC; Lin JY; Hsu SH; Lan WY; Kuo CS; Tian YF; Sun DP; Huang RS
    Int J Cancer; 2017 Dec; 141(12):2537-2550. PubMed ID: 28833104
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hypoxia induced Sonic Hedgehog signaling regulates cancer stemness, epithelial-to-mesenchymal transition and invasion in cholangiocarcinoma.
    Bhuria V; Xing J; Scholta T; Bui KC; Nguyen MLT; Malek NP; Bozko P; Plentz RR
    Exp Cell Res; 2019 Dec; 385(2):111671. PubMed ID: 31634481
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Nuclear factor-kappaB contributes to hedgehog signaling pathway activation through sonic hedgehog induction in pancreatic cancer.
    Nakashima H; Nakamura M; Yamaguchi H; Yamanaka N; Akiyoshi T; Koga K; Yamaguchi K; Tsuneyoshi M; Tanaka M; Katano M
    Cancer Res; 2006 Jul; 66(14):7041-9. PubMed ID: 16849549
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tumor necrosis factor α induces epithelial-mesenchymal transition and promotes metastasis via NF-κB signaling pathway-mediated TWIST expression in hypopharyngeal cancer.
    Yu L; Mu Y; Sa N; Wang H; Xu W
    Oncol Rep; 2014 Jan; 31(1):321-7. PubMed ID: 24220622
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hypoxia Accelerates Aggressiveness of Hepatocellular Carcinoma Cells Involving Oxidative Stress, Epithelial-Mesenchymal Transition and Non-Canonical Hedgehog Signaling.
    Liu Z; Tu K; Wang Y; Yao B; Li Q; Wang L; Dou C; Liu Q; Zheng X
    Cell Physiol Biochem; 2017; 44(5):1856-1868. PubMed ID: 29237157
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Activation of the Sonic Hedgehog pathway in thyroid neoplasms and its potential role in tumor cell proliferation.
    Xu X; Ding H; Rao G; Arora S; Saclarides CP; Esparaz J; Gattuso P; Solorzano CC; Prinz RA
    Endocr Relat Cancer; 2012 Apr; 19(2):167-79. PubMed ID: 22241722
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Sonic hedgehog and androgen signaling in tumor and stromal compartments drives epithelial-mesenchymal transition in prostate cancer.
    Yamamichi F; Shigemura K; Behnsawy HM; Meligy FY; Huang WC; Li X; Yamanaka K; Hanioka K; Miyake H; Tanaka K; Kawabata M; Shirakawa T; Fujisawa M
    Scand J Urol; 2014 Dec; 48(6):523-32. PubMed ID: 25356787
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hedgehog signaling pathway mediates invasion and metastasis of hepatocellular carcinoma via ERK pathway.
    Lu JT; Zhao WD; He W; Wei W
    Acta Pharmacol Sin; 2012 May; 33(5):691-700. PubMed ID: 22543708
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cyclopamine blocked the growth of colorectal cancer SW116 cells by modulating some target genes of Gli1 in vitro.
    Wu JY; Xu XF; Xu L; Niu PQ; Wang F; Hu GY; Wang XP; Guo CY
    Hepatogastroenterology; 2011; 58(110-111):1511-8. PubMed ID: 21940310
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Characterization of sonic hedgehog as a novel NF-kappaB target gene that promotes NF-kappaB-mediated apoptosis resistance and tumor growth in vivo.
    Kasperczyk H; Baumann B; Debatin KM; Fulda S
    FASEB J; 2009 Jan; 23(1):21-33. PubMed ID: 18772349
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Expression and regulation mechanisms of Sonic Hedgehog in breast cancer.
    Cui W; Wang LH; Wen YY; Song M; Li BL; Chen XL; Xu M; An SX; Zhao J; Lu YY; Mi XY; Wang EH
    Cancer Sci; 2010 Apr; 101(4):927-33. PubMed ID: 20180807
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activation of NF-κB by the RANKL/RANK system up-regulates snail and twist expressions and induces epithelial-to-mesenchymal transition in mammary tumor cell lines.
    Tsubaki M; Komai M; Fujimoto S; Itoh T; Imano M; Sakamoto K; Shimaoka H; Takeda T; Ogawa N; Mashimo K; Fujiwara D; Mukai J; Sakaguchi K; Satou T; Nishida S
    J Exp Clin Cancer Res; 2013 Sep; 32(1):62. PubMed ID: 24011086
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Phosphatidylethanolamine-binding protein 4 promotes the epithelial-to-mesenchymal transition in non-small cell lung cancer cells by activating the sonic hedgehog signaling pathway.
    Jian W; Bai Y; Li X; Kang J; Lei Y; Xue Y
    J Cell Biochem; 2019 Apr; 120(4):5386-5395. PubMed ID: 30367510
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hedgehog signaling pathway is inactive in colorectal cancer cell lines.
    Chatel G; Ganeff C; Boussif N; Delacroix L; Briquet A; Nolens G; Winkler R
    Int J Cancer; 2007 Dec; 121(12):2622-7. PubMed ID: 17683069
    [TBL] [Abstract][Full Text] [Related]  

  • 17. RANKL promotes migration and invasion of hepatocellular carcinoma cells via NF-κB-mediated epithelial-mesenchymal transition.
    Song FN; Duan M; Liu LZ; Wang ZC; Shi JY; Yang LX; Zhou J; Fan J; Gao Q; Wang XY
    PLoS One; 2014; 9(9):e108507. PubMed ID: 25268581
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tumor necrosis factor-α induces epithelial-mesenchymal transition of renal cell carcinoma cells via a nuclear factor kappa B-independent mechanism.
    Wu ST; Sun GH; Hsu CY; Huang CS; Wu YH; Wang HH; Sun KH
    Exp Biol Med (Maywood); 2011 Sep; 236(9):1022-9. PubMed ID: 21856755
    [TBL] [Abstract][Full Text] [Related]  

  • 19. KLF5 silence attenuates proliferation and epithelial-mesenchymal transition induction in Hep-2 cells through NF-κB signaling pathway.
    Liu FF; Dong L; Yang X; Li DJ; Shen YY; Liu ZL
    Eur Rev Med Pharmacol Sci; 2019 May; 23(9):3867-3875. PubMed ID: 31115014
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cooperatively transcriptional and epigenetic regulation of sonic hedgehog overexpression drives malignant potential of breast cancer.
    Duan ZH; Wang HC; Zhao DM; Ji XX; Song M; Yang XJ; Cui W
    Cancer Sci; 2015 Aug; 106(8):1084-91. PubMed ID: 25990213
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 39.