316 related articles for article (PubMed ID: 22461703)
1. Type 1 diabetes-associated IL2RA variation lowers IL-2 signaling and contributes to diminished CD4+CD25+ regulatory T cell function.
Garg G; Tyler JR; Yang JH; Cutler AJ; Downes K; Pekalski M; Bell GL; Nutland S; Peakman M; Todd JA; Wicker LS; Tree TI
J Immunol; 2012 May; 188(9):4644-53. PubMed ID: 22461703
[TBL] [Abstract][Full Text] [Related]
2. Multiple autoimmune-associated variants confer decreased IL-2R signaling in CD4+ CD25(hi) T cells of type 1 diabetic and multiple sclerosis patients.
Cerosaletti K; Schneider A; Schwedhelm K; Frank I; Tatum M; Wei S; Whalen E; Greenbaum C; Kita M; Buckner J; Long SA
PLoS One; 2013; 8(12):e83811. PubMed ID: 24376757
[TBL] [Abstract][Full Text] [Related]
3. Defects in IL-2R signaling contribute to diminished maintenance of FOXP3 expression in CD4(+)CD25(+) regulatory T-cells of type 1 diabetic subjects.
Long SA; Cerosaletti K; Bollyky PL; Tatum M; Shilling H; Zhang S; Zhang ZY; Pihoker C; Sanda S; Greenbaum C; Buckner JH
Diabetes; 2010 Feb; 59(2):407-15. PubMed ID: 19875613
[TBL] [Abstract][Full Text] [Related]
4. Acute Lipopolysaccharide-Induced Inflammation Lowers IL-2R Signaling and the Proliferative Potential of Regulatory T Cells.
Hsiung S; Moro A; Ban Y; Chen X; Savio AS; Hernandez R; Malek TR
Immunohorizons; 2020 Dec; 4(12):809-824. PubMed ID: 33334814
[TBL] [Abstract][Full Text] [Related]
5. T regulatory lymphocytes in type 1 diabetes: Impaired CD25 expression and IL-2 induced STAT5 phosphorylation in pediatric patients.
Parackova Z; Kayserova J; Danova K; Sismova K; Dudkova E; Sumnik Z; Kolouskova S; Lebl J; Stechova K; Sediva A
Autoimmunity; 2016 Dec; 49(8):523-531. PubMed ID: 27560779
[TBL] [Abstract][Full Text] [Related]
6. Decreased regulatory function of CD4
Sheikh V; Zamani A; Mahabadi-Ashtiyani E; Tarokhian H; Borzouei S; Alahgholi-Hajibehzad M
Scand J Immunol; 2018 Oct; 88(4):e12711. PubMed ID: 30270447
[TBL] [Abstract][Full Text] [Related]
7. Functional defects in CD4
Guo H; Zheng M; Zhang K; Yang F; Zhang X; Han Q; Chen ZN; Zhu P
Sci Rep; 2016 Nov; 6():37559. PubMed ID: 27901054
[TBL] [Abstract][Full Text] [Related]
8. A Crohn's Disease-associated IL2RA Enhancer Variant Determines the Balance of T Cell Immunity by Regulating Responsiveness to IL-2 Signalling.
Goldberg R; Clough JN; Roberts LB; Sanchez J; Kordasti S; Petrov N; Hertweck A; Lorenc A; Jackson I; Tasker S; Appios A; Omer O; Parkes M; Prescott N; Jenner RG; Irving PM; Lord GM
J Crohns Colitis; 2021 Dec; 15(12):2054-2065. PubMed ID: 34120187
[TBL] [Abstract][Full Text] [Related]
9. A long-lived IL-2 mutein that selectively activates and expands regulatory T cells as a therapy for autoimmune disease.
Peterson LB; Bell CJM; Howlett SK; Pekalski ML; Brady K; Hinton H; Sauter D; Todd JA; Umana P; Ast O; Waldhauer I; Freimoser-Grundschober A; Moessner E; Klein C; Hosse RJ; Wicker LS
J Autoimmun; 2018 Dec; 95():1-14. PubMed ID: 30446251
[TBL] [Abstract][Full Text] [Related]
10. IL-7 uniquely maintains FoxP3(+) adaptive Treg cells that reverse diabetes in NOD mice via integrin-β7-dependent localization.
Li CR; Deiro MF; Godebu E; Bradley LM
J Autoimmun; 2011 Nov; 37(3):217-27. PubMed ID: 21745722
[TBL] [Abstract][Full Text] [Related]
11. Natural Variation in Interleukin-2 Sensitivity Influences Regulatory T-Cell Frequency and Function in Individuals With Long-standing Type 1 Diabetes.
Yang JH; Cutler AJ; Ferreira RC; Reading JL; Cooper NJ; Wallace C; Clarke P; Smyth DJ; Boyce CS; Gao GJ; Todd JA; Wicker LS; Tree TI
Diabetes; 2015 Nov; 64(11):3891-902. PubMed ID: 26224887
[TBL] [Abstract][Full Text] [Related]
12. CCL11 increases the proportion of CD4+CD25+Foxp3+ Treg cells and the production of IL‑2 and TGF‑β by CD4+ T cells via the STAT5 signaling pathway.
Wang R; Huang K
Mol Med Rep; 2020 Jun; 21(6):2522-2532. PubMed ID: 32323817
[TBL] [Abstract][Full Text] [Related]
13. Low frequency of CD4+CD25+ Treg in SLE patients: a heritable trait associated with CTLA4 and TGFbeta gene variants.
Barreto M; Ferreira RC; Lourenço L; Moraes-Fontes MF; Santos E; Alves M; Carvalho C; Martins B; Andreia R; Viana JF; Vasconcelos C; Mota-Vieira L; Ferreira C; Demengeot J; Vicente AM
BMC Immunol; 2009 Jan; 10():5. PubMed ID: 19173720
[TBL] [Abstract][Full Text] [Related]
14. Two separate effects contribute to regulatory T cell defect in systemic lupus erythematosus patients and their unaffected relatives.
Costa N; Marques O; Godinho SI; Carvalho C; Leal B; Figueiredo AM; Vasconcelos C; Marinho A; Moraes-Fontes MF; Gomes da Costa A; Ponte C; Campanilho-Marques R; Cóias T; Martins AR; Viana JF; Lima M; Martins B; Fesel C
Clin Exp Immunol; 2017 Sep; 189(3):318-330. PubMed ID: 28542701
[TBL] [Abstract][Full Text] [Related]
15. The IL-2/CD25 pathway determines susceptibility to T1D in humans and NOD mice.
Dendrou CA; Wicker LS
J Clin Immunol; 2008 Nov; 28(6):685-96. PubMed ID: 18780166
[TBL] [Abstract][Full Text] [Related]
16. Reduced FOXP3(+) regulatory T cells in patients with primary sclerosing cholangitis are associated with IL2RA gene polymorphisms.
Sebode M; Peiseler M; Franke B; Schwinge D; Schoknecht T; Wortmann F; Quaas A; Petersen BS; Ellinghaus E; Baron U; Olek S; Wiegard C; Weiler-Normann C; Lohse AW; Herkel J; Schramm C
J Hepatol; 2014 May; 60(5):1010-6. PubMed ID: 24412607
[TBL] [Abstract][Full Text] [Related]
17. STAT5-signaling cytokines regulate the expression of FOXP3 in CD4+CD25+ regulatory T cells and CD4+CD25- effector T cells.
Passerini L; Allan SE; Battaglia M; Di Nunzio S; Alstad AN; Levings MK; Roncarolo MG; Bacchetta R
Int Immunol; 2008 Mar; 20(3):421-31. PubMed ID: 18270368
[TBL] [Abstract][Full Text] [Related]
18. Plasmodium falciparum-mediated induction of human CD25Foxp3 CD4 T cells is independent of direct TCR stimulation and requires IL-2, IL-10 and TGFbeta.
Scholzen A; Mittag D; Rogerson SJ; Cooke BM; Plebanski M
PLoS Pathog; 2009 Aug; 5(8):e1000543. PubMed ID: 19680449
[TBL] [Abstract][Full Text] [Related]
19. Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction.
Tang Q; Adams JY; Penaranda C; Melli K; Piaggio E; Sgouroudis E; Piccirillo CA; Salomon BL; Bluestone JA
Immunity; 2008 May; 28(5):687-97. PubMed ID: 18468463
[TBL] [Abstract][Full Text] [Related]
20. Tuning IL-2 signaling by ADP-ribosylation of CD25.
Teege S; Hann A; Miksiewicz M; MacMillan C; Rissiek B; Buck F; Menzel S; Nissen M; Bannas P; Haag F; Boyer O; Seman M; Adriouch S; Koch-Nolte F
Sci Rep; 2015 Mar; 5():8959. PubMed ID: 25753532
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
