86 related articles for article (PubMed ID: 22464954)
1. Therapeutic use of recombinant methionyl human leptin.
Vatier C; Gautier JF; Vigouroux C
Biochimie; 2012 Oct; 94(10):2116-25. PubMed ID: 22464954
[TBL] [Abstract][Full Text] [Related]
2. Recombinant methionyl human leptin therapy in replacement doses improves insulin resistance and metabolic profile in patients with lipoatrophy and metabolic syndrome induced by the highly active antiretroviral therapy.
Lee JH; Chan JL; Sourlas E; Raptopoulos V; Mantzoros CS
J Clin Endocrinol Metab; 2006 Jul; 91(7):2605-11. PubMed ID: 16636130
[TBL] [Abstract][Full Text] [Related]
3. The long-term effect of recombinant methionyl human leptin therapy on hyperandrogenism and menstrual function in female and pituitary function in male and female hypoleptinemic lipodystrophic patients.
Musso C; Cochran E; Javor E; Young J; Depaoli AM; Gorden P
Metabolism; 2005 Feb; 54(2):255-63. PubMed ID: 15690321
[TBL] [Abstract][Full Text] [Related]
4. Pharmacokinetics of subcutaneous recombinant methionyl human leptin administration in healthy subjects in the fed and fasting states: regulation by gender and adiposity.
Chan JL; Wong SL; Mantzoros CS
Clin Pharmacokinet; 2008; 47(11):753-64. PubMed ID: 18840030
[TBL] [Abstract][Full Text] [Related]
5. Changes in insulin sensitivity during leptin replacement therapy in leptin-deficient patients.
Paz-Filho G; Esposito K; Hurwitz B; Sharma A; Dong C; Andreev V; Delibasi T; Erol H; Ayala A; Wong ML; Licinio J
Am J Physiol Endocrinol Metab; 2008 Dec; 295(6):E1401-8. PubMed ID: 18854428
[TBL] [Abstract][Full Text] [Related]
6. Pharmacokinetics of recombinant methionyl human leptin after subcutaneous administration: variation of concentration-dependent parameters according to assay.
Chan JL; Wong SL; Orlova C; Raciti P; Mantzoros CS
J Clin Endocrinol Metab; 2007 Jun; 92(6):2307-11. PubMed ID: 17405837
[TBL] [Abstract][Full Text] [Related]
7. Recombinant methionyl human leptin administration activates signal transducer and activator of transcription 3 signaling in peripheral blood mononuclear cells in vivo and regulates soluble tumor necrosis factor-alpha receptor levels in humans with relative leptin deficiency.
Chan JL; Moschos SJ; Bullen J; Heist K; Li X; Kim YB; Kahn BB; Mantzoros CS
J Clin Endocrinol Metab; 2005 Mar; 90(3):1625-31. PubMed ID: 15613409
[TBL] [Abstract][Full Text] [Related]
8. Leptin therapy for partial lipodystrophy linked to a PPAR-gamma mutation.
Guettier JM; Park JY; Cochran EK; Poitou C; Basdevant A; Meier M; Clément K; Magré J; Gorden P
Clin Endocrinol (Oxf); 2008 Apr; 68(4):547-554. PubMed ID: 18076675
[TBL] [Abstract][Full Text] [Related]
9. Leptin reverses nonalcoholic steatohepatitis in patients with severe lipodystrophy.
Javor ED; Ghany MG; Cochran EK; Oral EA; DePaoli AM; Premkumar A; Kleiner DE; Gorden P
Hepatology; 2005 Apr; 41(4):753-60. PubMed ID: 15791619
[TBL] [Abstract][Full Text] [Related]
10. Hypothalamic melanocortin signaling and leptin resistance--perspective of therapeutic application for obesity-diabetes syndrome.
Masuzaki H; Tanaka T; Ebihara K; Hosoda K; Nakao K
Peptides; 2009 Jul; 30(7):1383-6. PubMed ID: 19394382
[TBL] [Abstract][Full Text] [Related]
11. Recombinant methionyl human leptin administration to achieve high physiologic or pharmacologic leptin levels does not alter circulating inflammatory marker levels in humans with leptin sufficiency or excess.
Chan JL; Bullen J; Stoyneva V; Depaoli AM; Addy C; Mantzoros CS
J Clin Endocrinol Metab; 2005 Mar; 90(3):1618-24. PubMed ID: 15613407
[TBL] [Abstract][Full Text] [Related]
12. Leptin hormonal kinetics in the fed state: effects of adiposity, age, and gender on endogenous leptin production and clearance rates.
Wong SL; DePaoli AM; Lee JH; Mantzoros CS
J Clin Endocrinol Metab; 2004 Jun; 89(6):2672-7. PubMed ID: 15181040
[TBL] [Abstract][Full Text] [Related]
13. Efficacy of recombinant methionyl human leptin therapy for the extreme insulin resistance of the Rabson-Mendenhall syndrome.
Cochran E; Young JR; Sebring N; DePaoli A; Oral EA; Gorden P
J Clin Endocrinol Metab; 2004 Apr; 89(4):1548-54. PubMed ID: 15070911
[TBL] [Abstract][Full Text] [Related]
14. Amylin improves the effect of leptin on insulin sensitivity in leptin-resistant diet-induced obese mice.
Kusakabe T; Ebihara K; Sakai T; Miyamoto L; Aotani D; Yamamoto Y; Yamamoto-Kataoka S; Aizawa-Abe M; Fujikura J; Hosoda K; Nakao K
Am J Physiol Endocrinol Metab; 2012 Apr; 302(8):E924-31. PubMed ID: 22275759
[TBL] [Abstract][Full Text] [Related]
15. Ten years of leptin replacement therapy.
Paz-Filho G; Wong ML; Licinio J
Obes Rev; 2011 May; 12(5):e315-23. PubMed ID: 21410864
[TBL] [Abstract][Full Text] [Related]
16. r-metHuLeptin improves highly active antiretroviral therapy-induced lipoatrophy and the metabolic syndrome, but not through altering circulating IGF and IGF-binding protein levels: observational and interventional studies in humans.
Brennan AM; Lee JH; Tsiodras S; Chan JL; Doweiko J; Chimienti SN; Wadhwa SG; Karchmer AW; Mantzoros CS
Eur J Endocrinol; 2009 Feb; 160(2):173-6. PubMed ID: 19029226
[TBL] [Abstract][Full Text] [Related]
17. Fat and energy partitioning: longitudinal observations in leptin-treated adults homozygous for a Lep mutation.
Heymsfield SB; Fong TM; Gantz I; Erondu N
Obesity (Silver Spring); 2006 Feb; 14(2):258-65. PubMed ID: 16571851
[TBL] [Abstract][Full Text] [Related]
18. Effect of three treatment schedules of recombinant methionyl human leptin on body weight in obese adults: a randomized, placebo-controlled trial.
Zelissen PM; Stenlof K; Lean ME; Fogteloo J; Keulen ET; Wilding J; Finer N; Rössner S; Lawrence E; Fletcher C; McCamish M;
Diabetes Obes Metab; 2005 Nov; 7(6):755-61. PubMed ID: 16219020
[TBL] [Abstract][Full Text] [Related]
19. The role of falling leptin levels in the neuroendocrine and metabolic adaptation to short-term starvation in healthy men.
Chan JL; Heist K; DePaoli AM; Veldhuis JD; Mantzoros CS
J Clin Invest; 2003 May; 111(9):1409-21. PubMed ID: 12727933
[TBL] [Abstract][Full Text] [Related]
20. Long-term efficacy of leptin replacement in patients with generalized lipodystrophy.
Javor ED; Cochran EK; Musso C; Young JR; Depaoli AM; Gorden P
Diabetes; 2005 Jul; 54(7):1994-2002. PubMed ID: 15983199
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]