BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

83 related articles for article (PubMed ID: 22468892)

  • 1. Improving potencies and properties of CD4 down-modulating CADA analogs.
    Bell TW; Demillo VG; Schols D; Vermeire K
    Expert Opin Drug Discov; 2012 Jan; 7(1):39-48. PubMed ID: 22468892
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design and cellular kinetics of dansyl-labeled CADA derivatives with anti-HIV and CD4 receptor down-modulating activity.
    Vermeire K; Lisco A; Grivel JC; Scarbrough E; Dey K; Duffy N; Margolis L; Bell TW; Schols D
    Biochem Pharmacol; 2007 Aug; 74(4):566-78. PubMed ID: 17603023
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Unsymmetrical cyclotriazadisulfonamide (CADA) compounds as human CD4 receptor down-modulating agents.
    Demillo VG; Goulinet-Mateo F; Kim J; Schols D; Vermeire K; Bell TW
    J Med Chem; 2011 Aug; 54(16):5712-21. PubMed ID: 21800875
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Syntheses and anti-HIV and human cluster of differentiation 4 (CD4) down-modulating potencies of pyridine-fused cyclotriazadisulfonamide (CADA) compounds.
    Lumangtad LA; Claeys E; Hamal S; Intasiri A; Basrai C; Yen-Pon E; Beenfeldt D; Vermeire K; Bell TW
    Bioorg Med Chem; 2020 Dec; 28(24):115816. PubMed ID: 33181479
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and structure-activity relationship studies of CD4 down-modulating cyclotriazadisulfonamide (CADA) analogues.
    Bell TW; Anugu S; Bailey P; Catalano VJ; Dey K; Drew MG; Duffy NH; Jin Q; Samala MF; Sodoma A; Welch WH; Schols D; Vermeire K
    J Med Chem; 2006 Feb; 49(4):1291-312. PubMed ID: 16480266
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The Anti-HIV potency of cyclotriazadisulfonamide analogs is directly correlated with their ability to down-modulate the CD4 receptor.
    Vermeire K; Bell TW; Choi HJ; Jin Q; Samala MF; Sodoma A; De Clercq E; Schols D
    Mol Pharmacol; 2003 Jan; 63(1):203-10. PubMed ID: 12488553
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Tuning Side Arm Electronics in Unsymmetrical Cyclotriazadisulfonamide (CADA) Endoplasmic Reticulum (ER) Translocation Inhibitors to Improve their Human Cluster of Differentiation 4 (CD4) Receptor Down-Modulating Potencies.
    Chawla R; Van Puyenbroeck V; Pflug NC; Sama A; Ali R; Schols D; Vermeire K; Bell TW
    J Med Chem; 2016 Mar; 59(6):2633-47. PubMed ID: 26974263
    [TBL] [Abstract][Full Text] [Related]  

  • 8. [Cyclotriazadisulfonamides as new and unique HIV entry inhibitors].
    Vermeire K
    Verh K Acad Geneeskd Belg; 2007; 69(5-6):231-47. PubMed ID: 18351208
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cyclotriazadisulfonamides: promising new CD4-targeted anti-HIV drugs.
    Vermeire K; Schols D
    J Antimicrob Chemother; 2005 Aug; 56(2):270-2. PubMed ID: 15980096
    [TBL] [Abstract][Full Text] [Related]  

  • 10. CADA, a potential anti-HIV microbicide that specifically targets the cellular CD4 receptor.
    Vermeire K; Brouwers J; Van Herrewege Y; Le Grand R; Vanham G; Augustijns P; Bell TW; Schols D
    Curr HIV Res; 2008 May; 6(3):246-56. PubMed ID: 18473788
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of N-phenyl-N'-(2,2,6,6-tetramethyl-piperidin-4-yl)-oxalamides as a new class of HIV-1 entry inhibitors that prevent gp120 binding to CD4.
    Zhao Q; Ma L; Jiang S; Lu H; Liu S; He Y; Strick N; Neamati N; Debnath AK
    Virology; 2005 Sep; 339(2):213-25. PubMed ID: 15996703
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel anti-HIV cyclotriazadisulfonamide derivatives as modeled by ligand- and receptor-based approaches.
    Pinheiro JR; Bitencourt M; da Cunha EF; Ramalho TC; Freitas MP
    Bioorg Med Chem; 2008 Feb; 16(4):1683-90. PubMed ID: 18053727
    [TBL] [Abstract][Full Text] [Related]  

  • 13. CADA inhibits human immunodeficiency virus and human herpesvirus 7 replication by down-modulation of the cellular CD4 receptor.
    Vermeire K; Zhang Y; Princen K; Hatse S; Samala MF; Dey K; Choi HJ; Ahn Y; Sodoma A; Snoeck R; Andrei G; De Clercq E; Bell TW; Schols D
    Virology; 2002 Oct; 302(2):342-53. PubMed ID: 12441078
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and structure-activity relationships of azamacrocyclic C-X-C chemokine receptor 4 antagonists: analogues containing a single azamacrocyclic ring are potent inhibitors of T-cell tropic (X4) HIV-1 replication.
    Bridger GJ; Skerlj RT; Hernandez-Abad PE; Bogucki DE; Wang Z; Zhou Y; Nan S; Boehringer EM; Wilson T; Crawford J; Metz M; Hatse S; Princen K; De Clercq E; Schols D
    J Med Chem; 2010 Feb; 53(3):1250-60. PubMed ID: 20043638
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A Proteomic Survey Indicates Sortilin as a Secondary Substrate of the ER Translocation Inhibitor Cyclotriazadisulfonamide (CADA).
    Van Puyenbroeck V; Claeys E; Schols D; Bell TW; Vermeire K
    Mol Cell Proteomics; 2017 Feb; 16(2):157-167. PubMed ID: 27998951
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Soluble gC1q-R/p33, a cell protein that binds to the globular "heads" of C1q, effectively inhibits the growth of HIV-1 strains in cell cultures.
    Szabó J; Cervenák L; Tóth FD; Prohászka Z; Horváth L; Kerekes K; Beck Z; Bácsi A; Erdei A; Peerschke EI; Füst G; Ghebrehiwet B
    Clin Immunol; 2001 May; 99(2):222-31. PubMed ID: 11318594
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Specific CD4 down-modulating compounds with potent anti-HIV activity.
    Vermeire K; Schols D
    J Leukoc Biol; 2003 Nov; 74(5):667-75. PubMed ID: 12960237
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and biological properties of novel pyridinioalkanoyl thiolesters (PATE) as anti-HIV-1 agents that target the viral nucleocapsid protein zinc fingers.
    Turpin JA; Song Y; Inman JK; Huang M; Wallqvist A; Maynard A; Covell DG; Rice WG; Appella E
    J Med Chem; 1999 Jan; 42(1):67-86. PubMed ID: 9888834
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of 3,4-dihydropyrimidin-2(1H)-ones with inhibitory activity against HIV-1 replication.
    Kim J; Park C; Ok T; So W; Jo M; Seo M; Kim Y; Sohn JH; Park Y; Ju MK; Kim J; Han SJ; Kim TH; Cechetto J; Nam J; Sommer P; No Z
    Bioorg Med Chem Lett; 2012 Mar; 22(5):2119-24. PubMed ID: 22305583
    [TBL] [Abstract][Full Text] [Related]  

  • 20. HIV-chemotherapy and -prophylaxis: new drugs, leads and approaches.
    De Clercq E
    Int J Biochem Cell Biol; 2004 Sep; 36(9):1800-22. PubMed ID: 15183346
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.