415 related articles for article (PubMed ID: 22470521)
1. Amyloid precursor protein (APP) mediated regulation of ganglioside homeostasis linking Alzheimer's disease pathology with ganglioside metabolism.
Grimm MO; Zinser EG; Grösgen S; Hundsdörfer B; Rothhaar TL; Burg VK; Kaestner L; Bayer TA; Lipp P; Müller U; Grimm HS; Hartmann T
PLoS One; 2012; 7(3):e34095. PubMed ID: 22470521
[TBL] [Abstract][Full Text] [Related]
2. Brain gangliosides of a transgenic mouse model of Alzheimer's disease with deficiency in GD3-synthase: expression of elevated levels of a cholinergic-specific ganglioside, GT1aα.
Ariga T; Itokazu Y; McDonald MP; Hirabayashi Y; Ando S; Yu RK
ASN Neuro; 2013 May; 5(2):141-8. PubMed ID: 23565921
[TBL] [Abstract][Full Text] [Related]
3. Elimination of GD3 synthase improves memory and reduces amyloid-beta plaque load in transgenic mice.
Bernardo A; Harrison FE; McCord M; Zhao J; Bruchey A; Davies SS; Jackson Roberts L; Mathews PM; Matsuoka Y; Ariga T; Yu RK; Thompson R; McDonald MP
Neurobiol Aging; 2009 Nov; 30(11):1777-91. PubMed ID: 18258340
[TBL] [Abstract][Full Text] [Related]
4. Upregulation of PGC-1α expression by Alzheimer's disease-associated pathway: presenilin 1/amyloid precursor protein (APP)/intracellular domain of APP.
Robinson A; Grösgen S; Mett J; Zimmer VC; Haupenthal VJ; Hundsdörfer B; Stahlmann CP; Slobodskoy Y; Müller UC; Hartmann T; Stein R; Grimm MO
Aging Cell; 2014 Apr; 13(2):263-72. PubMed ID: 24304563
[TBL] [Abstract][Full Text] [Related]
5. Regulatory feedback cycle of the insulin-degrading enzyme and the amyloid precursor protein intracellular domain: Implications for Alzheimer's disease.
Lauer AA; Mett J; Janitschke D; Thiel A; Stahlmann CP; Bachmann CM; Ritzmann F; Schrul B; Müller UC; Stein R; Riemenschneider M; Grimm HS; Hartmann T; Grimm MOW
Aging Cell; 2020 Nov; 19(11):e13264. PubMed ID: 33128835
[TBL] [Abstract][Full Text] [Related]
6. Ganglioside Hp-s1 Analogue Inhibits Amyloidogenic Toxicity in Alzheimer's Disease Model Cells.
Tsai YF; Yang DJ; Ngo TH; Shih CH; Wu YF; Lee CK; Phraekanjanavichid V; Yen SF; Kao SH; Lee HM; Huang VS; Shieh JC; Lin YF
ACS Chem Neurosci; 2019 Jan; 10(1):528-536. PubMed ID: 30346715
[TBL] [Abstract][Full Text] [Related]
7. Intracellular amyloid precursor protein sorting and amyloid-β secretion are regulated by Src-mediated phosphorylation of Mint2.
Chaufty J; Sullivan SE; Ho A
J Neurosci; 2012 Jul; 32(28):9613-25. PubMed ID: 22787047
[TBL] [Abstract][Full Text] [Related]
8. Ganglioside-Dependent Neural Stem Cell Proliferation in Alzheimer's Disease Model Mice.
Koon NA; Itokazu Y; Yu RK
ASN Neuro; 2015; 7(6):. PubMed ID: 26699276
[TBL] [Abstract][Full Text] [Related]
9. PS dependent APP cleavage regulates glucosylceramide synthase and is affected in Alzheimer's disease.
Grimm MO; Hundsdörfer B; Grösgen S; Mett J; Zimmer VC; Stahlmann CP; Haupenthal VJ; Rothhaar TL; Lehmann J; Pätzold A; Zinser EG; Tanila H; Shen J; Müller U; Grimm HS; Hartmann T
Cell Physiol Biochem; 2014; 34(1):92-110. PubMed ID: 24977484
[TBL] [Abstract][Full Text] [Related]
10. Evidence that enzyme processivity mediates differential Aβ production by PS1 and PS2.
Pintchovski SA; Schenk DB; Basi GS
Curr Alzheimer Res; 2013 Jan; 10(1):4-10. PubMed ID: 22950863
[TBL] [Abstract][Full Text] [Related]
11. Neuronal activity and secreted amyloid β lead to altered amyloid β precursor protein and presenilin 1 interactions.
Li X; Uemura K; Hashimoto T; Nasser-Ghodsi N; Arimon M; Lill CM; Palazzolo I; Krainc D; Hyman BT; Berezovska O
Neurobiol Dis; 2013 Feb; 50():127-34. PubMed ID: 23064434
[TBL] [Abstract][Full Text] [Related]
12. Melatonin Induction of APP Intracellular Domain 50 SUMOylation Alleviates AD through Enhanced Transcriptional Activation and Aβ Degradation.
Liu YC; Hsu WL; Ma YL; Lee EHY
Mol Ther; 2021 Jan; 29(1):376-395. PubMed ID: 32950104
[TBL] [Abstract][Full Text] [Related]
13. Amyloidogenic processing of amyloid β protein precursor (APP) is enhanced in the brains of alcadein α-deficient mice.
Gotoh N; Saito Y; Hata S; Saito H; Ojima D; Murayama C; Shigeta M; Abe T; Konno D; Matsuzaki F; Suzuki T; Yamamoto T
J Biol Chem; 2020 Jul; 295(28):9650-9662. PubMed ID: 32467230
[TBL] [Abstract][Full Text] [Related]
14. Huntingtin associated protein 1 regulates trafficking of the amyloid precursor protein and modulates amyloid beta levels in neurons.
Yang GZ; Yang M; Lim Y; Lu JJ; Wang TH; Qi JG; Zhong JH; Zhou XF
J Neurochem; 2012 Sep; 122(5):1010-22. PubMed ID: 22731248
[TBL] [Abstract][Full Text] [Related]
15. Calpain Activation in Alzheimer's Model Mice Is an Artifact of APP and Presenilin Overexpression.
Saito T; Matsuba Y; Yamazaki N; Hashimoto S; Saido TC
J Neurosci; 2016 Sep; 36(38):9933-6. PubMed ID: 27656030
[TBL] [Abstract][Full Text] [Related]
16. Hydrophilic loop 1 of Presenilin-1 and the APP GxxxG transmembrane motif regulate γ-secretase function in generating Alzheimer-causing Aβ peptides.
Liu L; Lauro BM; Wolfe MS; Selkoe DJ
J Biol Chem; 2021; 296():100393. PubMed ID: 33571524
[TBL] [Abstract][Full Text] [Related]
17. Small things matter: Implications of APP intracellular domain AICD nuclear signaling in the progression and pathogenesis of Alzheimer's disease.
Bukhari H; Glotzbach A; Kolbe K; Leonhardt G; Loosse C; Müller T
Prog Neurobiol; 2017 Sep; 156():189-213. PubMed ID: 28587768
[TBL] [Abstract][Full Text] [Related]
18. Cryptotanshinone, a compound from Salvia miltiorrhiza modulates amyloid precursor protein metabolism and attenuates beta-amyloid deposition through upregulating alpha-secretase in vivo and in vitro.
Mei Z; Zhang F; Tao L; Zheng W; Cao Y; Wang Z; Tang S; Le K; Chen S; Pi R; Liu P
Neurosci Lett; 2009 Mar; 452(2):90-5. PubMed ID: 19154776
[TBL] [Abstract][Full Text] [Related]
19. Genes and mechanisms involved in beta-amyloid generation and Alzheimer's disease.
Steiner H; Capell A; Leimer U; Haass C
Eur Arch Psychiatry Clin Neurosci; 1999; 249(6):266-70. PubMed ID: 10653281
[TBL] [Abstract][Full Text] [Related]
20. Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets.
Evin G; Zhu A; Holsinger RM; Masters CL; Li QX
J Neurosci Res; 2003 Nov; 74(3):386-92. PubMed ID: 14598315
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]