These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

410 related articles for article (PubMed ID: 22470521)

  • 1. Amyloid precursor protein (APP) mediated regulation of ganglioside homeostasis linking Alzheimer's disease pathology with ganglioside metabolism.
    Grimm MO; Zinser EG; Grösgen S; Hundsdörfer B; Rothhaar TL; Burg VK; Kaestner L; Bayer TA; Lipp P; Müller U; Grimm HS; Hartmann T
    PLoS One; 2012; 7(3):e34095. PubMed ID: 22470521
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Brain gangliosides of a transgenic mouse model of Alzheimer's disease with deficiency in GD3-synthase: expression of elevated levels of a cholinergic-specific ganglioside, GT1aα.
    Ariga T; Itokazu Y; McDonald MP; Hirabayashi Y; Ando S; Yu RK
    ASN Neuro; 2013 May; 5(2):141-8. PubMed ID: 23565921
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Elimination of GD3 synthase improves memory and reduces amyloid-beta plaque load in transgenic mice.
    Bernardo A; Harrison FE; McCord M; Zhao J; Bruchey A; Davies SS; Jackson Roberts L; Mathews PM; Matsuoka Y; Ariga T; Yu RK; Thompson R; McDonald MP
    Neurobiol Aging; 2009 Nov; 30(11):1777-91. PubMed ID: 18258340
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Upregulation of PGC-1α expression by Alzheimer's disease-associated pathway: presenilin 1/amyloid precursor protein (APP)/intracellular domain of APP.
    Robinson A; Grösgen S; Mett J; Zimmer VC; Haupenthal VJ; Hundsdörfer B; Stahlmann CP; Slobodskoy Y; Müller UC; Hartmann T; Stein R; Grimm MO
    Aging Cell; 2014 Apr; 13(2):263-72. PubMed ID: 24304563
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulatory feedback cycle of the insulin-degrading enzyme and the amyloid precursor protein intracellular domain: Implications for Alzheimer's disease.
    Lauer AA; Mett J; Janitschke D; Thiel A; Stahlmann CP; Bachmann CM; Ritzmann F; Schrul B; Müller UC; Stein R; Riemenschneider M; Grimm HS; Hartmann T; Grimm MOW
    Aging Cell; 2020 Nov; 19(11):e13264. PubMed ID: 33128835
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ganglioside Hp-s1 Analogue Inhibits Amyloidogenic Toxicity in Alzheimer's Disease Model Cells.
    Tsai YF; Yang DJ; Ngo TH; Shih CH; Wu YF; Lee CK; Phraekanjanavichid V; Yen SF; Kao SH; Lee HM; Huang VS; Shieh JC; Lin YF
    ACS Chem Neurosci; 2019 Jan; 10(1):528-536. PubMed ID: 30346715
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Intracellular amyloid precursor protein sorting and amyloid-β secretion are regulated by Src-mediated phosphorylation of Mint2.
    Chaufty J; Sullivan SE; Ho A
    J Neurosci; 2012 Jul; 32(28):9613-25. PubMed ID: 22787047
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ganglioside-Dependent Neural Stem Cell Proliferation in Alzheimer's Disease Model Mice.
    Koon NA; Itokazu Y; Yu RK
    ASN Neuro; 2015; 7(6):. PubMed ID: 26699276
    [TBL] [Abstract][Full Text] [Related]  

  • 9. PS dependent APP cleavage regulates glucosylceramide synthase and is affected in Alzheimer's disease.
    Grimm MO; Hundsdörfer B; Grösgen S; Mett J; Zimmer VC; Stahlmann CP; Haupenthal VJ; Rothhaar TL; Lehmann J; Pätzold A; Zinser EG; Tanila H; Shen J; Müller U; Grimm HS; Hartmann T
    Cell Physiol Biochem; 2014; 34(1):92-110. PubMed ID: 24977484
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Evidence that enzyme processivity mediates differential Aβ production by PS1 and PS2.
    Pintchovski SA; Schenk DB; Basi GS
    Curr Alzheimer Res; 2013 Jan; 10(1):4-10. PubMed ID: 22950863
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Neuronal activity and secreted amyloid β lead to altered amyloid β precursor protein and presenilin 1 interactions.
    Li X; Uemura K; Hashimoto T; Nasser-Ghodsi N; Arimon M; Lill CM; Palazzolo I; Krainc D; Hyman BT; Berezovska O
    Neurobiol Dis; 2013 Feb; 50():127-34. PubMed ID: 23064434
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Melatonin Induction of APP Intracellular Domain 50 SUMOylation Alleviates AD through Enhanced Transcriptional Activation and Aβ Degradation.
    Liu YC; Hsu WL; Ma YL; Lee EHY
    Mol Ther; 2021 Jan; 29(1):376-395. PubMed ID: 32950104
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Amyloidogenic processing of amyloid β protein precursor (APP) is enhanced in the brains of alcadein α-deficient mice.
    Gotoh N; Saito Y; Hata S; Saito H; Ojima D; Murayama C; Shigeta M; Abe T; Konno D; Matsuzaki F; Suzuki T; Yamamoto T
    J Biol Chem; 2020 Jul; 295(28):9650-9662. PubMed ID: 32467230
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Huntingtin associated protein 1 regulates trafficking of the amyloid precursor protein and modulates amyloid beta levels in neurons.
    Yang GZ; Yang M; Lim Y; Lu JJ; Wang TH; Qi JG; Zhong JH; Zhou XF
    J Neurochem; 2012 Sep; 122(5):1010-22. PubMed ID: 22731248
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Calpain Activation in Alzheimer's Model Mice Is an Artifact of APP and Presenilin Overexpression.
    Saito T; Matsuba Y; Yamazaki N; Hashimoto S; Saido TC
    J Neurosci; 2016 Sep; 36(38):9933-6. PubMed ID: 27656030
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hydrophilic loop 1 of Presenilin-1 and the APP GxxxG transmembrane motif regulate γ-secretase function in generating Alzheimer-causing Aβ peptides.
    Liu L; Lauro BM; Wolfe MS; Selkoe DJ
    J Biol Chem; 2021; 296():100393. PubMed ID: 33571524
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Small things matter: Implications of APP intracellular domain AICD nuclear signaling in the progression and pathogenesis of Alzheimer's disease.
    Bukhari H; Glotzbach A; Kolbe K; Leonhardt G; Loosse C; Müller T
    Prog Neurobiol; 2017 Sep; 156():189-213. PubMed ID: 28587768
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cryptotanshinone, a compound from Salvia miltiorrhiza modulates amyloid precursor protein metabolism and attenuates beta-amyloid deposition through upregulating alpha-secretase in vivo and in vitro.
    Mei Z; Zhang F; Tao L; Zheng W; Cao Y; Wang Z; Tang S; Le K; Chen S; Pi R; Liu P
    Neurosci Lett; 2009 Mar; 452(2):90-5. PubMed ID: 19154776
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Genes and mechanisms involved in beta-amyloid generation and Alzheimer's disease.
    Steiner H; Capell A; Leimer U; Haass C
    Eur Arch Psychiatry Clin Neurosci; 1999; 249(6):266-70. PubMed ID: 10653281
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets.
    Evin G; Zhu A; Holsinger RM; Masters CL; Li QX
    J Neurosci Res; 2003 Nov; 74(3):386-92. PubMed ID: 14598315
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.