These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

74 related articles for article (PubMed ID: 22472692)

  • 1. 5-Benzothiazole substituted pyrimidine derivatives as HCV replication (replicase) inhibitors.
    Arasappan A; Bennett F; Girijavallabhan V; Huang Y; Huelgas R; Alvarez C; Chen L; Gavalas S; Kim SH; Kosinski A; Pinto P; Rizvi R; Rossman R; Shankar B; Tong L; Velazquez F; Venkatraman S; Verma VA; Kozlowski J; Shih NY; Piwinski JJ; MacCoss M; Kwong CD; Clark JL; Fowler AT; Geng F; Kezar HS; Roychowdhury A; Reynolds RC; Maddry JA; Ananthan S; Secrist JA; Li C; Chase R; Curry S; Huang HC; Tong X; Njoroge FG
    Bioorg Med Chem Lett; 2012 May; 22(9):3229-34. PubMed ID: 22472692
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and SAR of pyridothiazole substituted pyrimidine derived HCV replication inhibitors.
    Girijavallabhan VM; Alvarez C; Bennett F; Chen L; Gavalas S; Huang Y; Kim SH; Kosinski A; Pinto P; Rizvi R; Rossman R; Shankar B; Tong L; Velazquez F; Venkatraman S; Verma VA; Kozlowski J; Shih NY; Piwinski JJ; MacCoss M; Kwong CD; Bansal N; Clark JL; Fowler AT; Kezar HS; Valiyaveettil J; Reynolds RC; Maddry JA; Ananthan S; Secrist JA; Li C; Chase R; Curry S; Huang HC; Tong X; Njoroge FG; Arasappan A
    Bioorg Med Chem Lett; 2012 Sep; 22(17):5652-7. PubMed ID: 22858143
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel substituted pyrimidines as HCV replication (replicase) inhibitors.
    Kwong CD; Clark JL; Fowler AT; Geng F; Kezar HS; Roychowdhury A; Reynolds RC; Maddry JA; Ananthan S; Secrist JA; Shih NY; Piwinski JJ; Li C; Feld B; Huang HC; Tong X; George Njoroge F; Arasappan A
    Bioorg Med Chem Lett; 2012 Jan; 22(2):1160-4. PubMed ID: 22178556
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and SAR of geminal substitutions at the C5' carbosugar position of pyrimidine-derived HCV inhibitors.
    Verma VA; Rossman R; Bennett F; Chen L; Gavalas S; Girijavallabhan V; Huang Y; Kim SH; Kosinski A; Pinto P; Rizvi R; Shankar B; Tong L; Velazquez F; Venkatraman S; Kozlowski J; MacCoss M; Kwong CD; Bansal N; Kezar HS; Reynolds RC; Maddry JA; Ananthan S; Secrist JA; Li C; Chase R; Curry S; Huang HC; Tong X; Njoroge FG; Arasappan A
    Bioorg Med Chem Lett; 2012 Nov; 22(22):6967-73. PubMed ID: 23036957
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pyridofuran substituted pyrimidine derivatives as HCV replication (replicase) inhibitors.
    Bennett F; Kezar HS; Girijavallabhan V; Huang Y; Huelgas R; Rossman R; Shih NY; Piwinski JJ; MacCoss M; Kwong CD; Clark JL; Fowler AT; Geng F; Roychowdhury A; Reynolds RC; Maddry JA; Ananthan S; Secrist JA; Li C; Chase R; Curry S; Huang HC; Tong X; George Njoroge F; Arasappan A
    Bioorg Med Chem Lett; 2012 Aug; 22(15):5144-9. PubMed ID: 22814211
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Novel hepatitis C virus replicon inhibitors: synthesis and structure-activity relationships of fused pyrimidine derivatives.
    Krueger AC; Madigan DL; Beno DW; Betebenner DA; Carrick R; Green BE; He W; Liu D; Maring CJ; McDaniel KF; Mo H; Molla A; Motter CE; Pilot-Matias TJ; Tufano MD; Kempf DJ
    Bioorg Med Chem Lett; 2012 Mar; 22(6):2212-5. PubMed ID: 22342631
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and anti-hepatitis C virus (HCV) activity of 3'-C-substituted-methyl pyrimidine and purine nucleosides.
    Choi WJ; Kim YM; Kim HO; Lee HW; Kim DE; Park KS; Chong Y; Jeong LS
    Bioorg Med Chem; 2010 Jul; 18(13):4812-20. PubMed ID: 20627592
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Exploration of the in vitro antiviral activity of a series of new pyrimidine analogues on the replication of HIV and HCV.
    Jafar NN; Al-Masoudi NA; Baqir SJ; Leyssen P; Pannecouque C
    Antivir Chem Chemother; 2012 Sep; 23(3):103-12. PubMed ID: 23010622
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure-activity relationship (SAR) optimization of 6-(indol-2-yl)pyridine-3-sulfonamides: identification of potent, selective, and orally bioavailable small molecules targeting hepatitis C (HCV) NS4B.
    Zhang N; Zhang X; Zhu J; Turpoff A; Chen G; Morrill C; Huang S; Lennox W; Kakarla R; Liu R; Li C; Ren H; Almstead N; Venkatraman S; Njoroge FG; Gu Z; Clausen V; Graci J; Jung SP; Zheng Y; Colacino JM; Lahser F; Sheedy J; Mollin A; Weetall M; Nomeir A; Karp GM
    J Med Chem; 2014 Mar; 57(5):2121-35. PubMed ID: 24266880
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Computer-aided identification, synthesis and evaluation of substituted thienopyrimidines as novel inhibitors of HCV replication.
    Bassetto M; Leyssen P; Neyts J; Yerukhimovich MM; Frick DN; Brancale A
    Eur J Med Chem; 2016 Nov; 123():31-47. PubMed ID: 27474921
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Discovery of potent sulfonamide P4-capped ketoamide second generation inhibitors of hepatitis C virus NS3 serine protease with favorable pharmacokinetic profiles in preclinical species.
    Bogen SL; Arasappan A; Velazquez F; Blackman M; Huelgas R; Pan W; Siegel E; Nair LG; Venkatraman S; Guo Z; Doll R; Shih NY; Njoroge FG
    Bioorg Med Chem; 2010 Mar; 18(5):1854-65. PubMed ID: 20149666
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis, and antiviral activity of 2'-deoxy-2'-fluoro-2'-C-methylcytidine, a potent inhibitor of hepatitis C virus replication.
    Clark JL; Hollecker L; Mason JC; Stuyver LJ; Tharnish PM; Lostia S; McBrayer TR; Schinazi RF; Watanabe KA; Otto MJ; Furman PA; Stec WJ; Patterson SE; Pankiewicz KW
    J Med Chem; 2005 Aug; 48(17):5504-8. PubMed ID: 16107149
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis of 9-(2-beta-C-methyl-beta-d-ribofuranosyl)-6-substituted purine derivatives as inhibitors of HCV RNA replication.
    Ding Y; Girardet JL; Hong Z; Lai VC; An H; Koh YH; Shaw SZ; Zhong W
    Bioorg Med Chem Lett; 2005 Feb; 15(3):709-13. PubMed ID: 15664842
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Novel potent inhibitors of hepatitis C virus (HCV) NS3 protease with cyclic sulfonyl P3 cappings.
    Chen KX; Vibulbhan B; Yang W; Nair LG; Tong X; Cheng KC; Njoroge FG
    Bioorg Med Chem Lett; 2009 Feb; 19(4):1105-9. PubMed ID: 19168351
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Phosphoramidate ProTides of 2'-C-methylguanosine as highly potent inhibitors of hepatitis C virus. Study of their in vitro and in vivo properties.
    McGuigan C; Gilles A; Madela K; Aljarah M; Holl S; Jones S; Vernachio J; Hutchins J; Ames B; Bryant KD; Gorovits E; Ganguly B; Hunley D; Hall A; Kolykhalov A; Liu Y; Muhammad J; Raja N; Walters R; Wang J; Chamberlain S; Henson G
    J Med Chem; 2010 Jul; 53(13):4949-57. PubMed ID: 20527890
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Selective inhibitors of hepatitis C virus replication.
    Neyts J
    Antiviral Res; 2006 Sep; 71(2-3):363-71. PubMed ID: 16843538
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hepatitis C virus resistance to protease inhibitors.
    Halfon P; Locarnini S
    J Hepatol; 2011 Jul; 55(1):192-206. PubMed ID: 21284949
    [TBL] [Abstract][Full Text] [Related]  

  • 18. High-throughput screening of HCV RNA replication inhibitors by means of a reporter replicon system.
    Hao W; Duggal R
    Methods Mol Biol; 2009; 510():243-50. PubMed ID: 19009266
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Serine palmitoyltransferase inhibitor suppresses HCV replication in a mouse model.
    Umehara T; Sudoh M; Yasui F; Matsuda C; Hayashi Y; Chayama K; Kohara M
    Biochem Biophys Res Commun; 2006 Jul; 346(1):67-73. PubMed ID: 16750511
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The design, synthesis, and antiviral activity of 4'-azidocytidine analogues against hepatitis C virus replication: the discovery of 4'-azidoarabinocytidine.
    Smith DB; Kalayanov G; Sund C; Winqvist A; Pinho P; Maltseva T; Morisson V; Leveque V; Rajyaguru S; Le Pogam S; Najera I; Benkestock K; Zhou XX; Maag H; Cammack N; Martin JA; Swallow S; Johansson NG; Klumpp K; Smith M
    J Med Chem; 2009 Jan; 52(1):219-23. PubMed ID: 19055482
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.